• 한국학교보건학회지
• /
• 제15권1호
• /
• pp.107-121
• /
• 2002

In this study we analysed time allotment and the contents of a health textbook and its teacher's guide book of the 7th elementary curriculum. We intended to offer the basic data needed to establish the single health education. So the analysed results are as follows according to the health education model developed by the korean nursing association and health teachers' meeting and the teaching time allotment presented by the teacher's guide book. It's goal is practice in regular class time of the subjects for the time and contents of health education in the 7th elementary curriculum. The total class periods of health education of the 7th elementary curriculum are 229 hours and annual periods of health education per year are an average of 38 hours. The health education of the 7th elementary curriculum is separated into the 9 following subjects: Wise life, Pleasant life, Righteous life, We are 1st grade, Physical education, Science, Social studies, moral education and Practical course. The health education of the 6th elementary curriculum was combined with the units of physical education, but in the 7th curriculum it must be separated by a single, required health subject. The contents of health education of the 7th elementary curriculum is mostly dominated by units of community and environmental health with a total of 55 hours (24%). Therefore, the units of home health and social health, development of physical strength are fairly insignificant. The newly added contents in the 7th curriculum are "pregnancy and child birth, the protection and counterplan from rape, the reasons and prevention of stress, the reasons and the treatment of obesity, the damage of smoking and drinking, etc. According to the result above, we must establish the criteria for each year's health education in the 8th elementary curriculum. The contents of mental health, home health and social health should be revised and added new items. The health education that is separated in some subjects now must be established as a systematically integrated health education.

• 대한수의학회지
• /
• 제32권1호
• /
• pp.1-6
• /
• 1992

The turnover time of the mucosal epithelium in the small intestine(jejunum and ilium) and large interstine(cecum), and the cells in the lamina propria of the small intestine was investigated with the radioautography in mice at various times after single injection of $^3H$-thymidine. Twenty suckling mice were sacrified at each of the following time intervals after injection ; 2 hrs, 1, 3, 5. 7, 14 and 17 days. 1. The labeled index of the epithelial cells in the crypt and the villus of the small intestine averaged 98.7% and 1.3% at 2 hrs, 982% and 1.8% at 1 day, 18.7% and 81.3% at 3 days, 6.3% and 93.7% at 5 days, respectively. The labeled index of the epithelial cells of the crypt-base, the upper-crypt and the mucosal surface in the large intestine averaged 71.8%, 28.2% and 0% at 2 hrs, 45%. 54.2% and 0% at 1 day, 17.2%, 54.5% and 28.2% at 3 days, 10.2%, 32.4% and 57.4% at 5 days, respectively. This result suggested that the turnover time of all the epithelial cells migrating from crypts to villi in the direction of the villus tips was calculated to be less than 5 days, and also the longest turnover time was calculated to be no longer than 7 day. 2. The labeled index of the total cells in the lamina propria of the small intestine averaged 6.2-7% at 2 hrs to 5 days, 4.7% at 7 days 2.6% at 17 days and this index is tend to be decreased moderately at 7 days and severely at 17 days. So this result suggested that the turnover time of the cells with the shorter cycle duration in the lamina propria of the small intestine were less than 5 days and that of the cells with the longer cycle duration more than 17 days.

• 한국작물학회지
• /
• 제39권4호
• /
• pp.348-352
• /
• 1994

콩 저장 단백질의 대부분은 globulin이며, 이중 7S와 11S가 70% 이상을 차지한다. 따라서 콩 단백질의 조성개량을 위해서는 11S/7S 비율 조정이 우선되는데, 본 연구에서는 몇가지 콩 품종을 사용하여 7S와 11S를 분리 확인하고, 이들 분획 단백질을 이용한 두부제조시험을 실시하였다. 7S와11S는 콩 분말을 탈지한 후 pH를 조정하고 원심분리를 이용함으로써 분획할 수 있었고, 전기영동상(SDS-PAGE)에서 이를 확인할 수 있었다. 공시계통들의 11S/7S 비율은 1.29∼1.38을 나타내어 계통간 차이가 없었다. 한편 콩 종실 단백질을 7S와 11S로 분획한 후 7S와 11S를 비율별로 혼합하여 두부를 제조하고 물성을 측정한 결과 11S량이 많아질수록 두부의 경도, 탄력성, 응집성 등이 높게 나타난다. 따라서 11S와 7S의 비율을 조정함으로써 여러가지 용도에 알맞는 식품개발이 가능하리라 판단된다.

• 천문학논총
• /
• 제7권1호
• /
• pp.1-7
• /
• 1992

We may consider the following three fundamental epistemological questions concerning cosmology. Can cosmology at last understand the origin of the universe? Can computers at last create? Can life be formed at last synthetically? These questions are in some sense related to the liar paradox containing the self-reference and, therefore. may not be answered by recursive processes in finite time. There are, however. various implications such that the chaos may break the trap of the self-reference paradox. In other words, Goedel's incompleteness theorem would not apply to chaos, even if the chaos can be generated by recursive processes. Internal relations among cosmology, epistemology and chaos must be investigated in greater detail.

• Reproductive and Developmental Biology
• /
• 제39권4호
• /
• pp.105-115
• /
• 2015

Toll-like receptor 7 (TLR7) is critical for the triggering of innate immune response by recognizing the conserved molecular patterns of single-stranded RNA (ssRNA) viruses and mediated antigenic adaptive immunity. To understand how TLR7 distinguish pathogen-derived molecular patterns from the host self, it is essential to be able to identify TLR7 receptor interaction interfaces, such as active sites or R848-agonist binding sites. The functional interfaces of TLR7 can serve as targets for structure-based drug design in studying the TLR7 receptor's structure-function relationship. In contrast to mammalian TLR7, chicken TLR7 (chTLR7) is unknown for its important biological function. Therefore, it has been targeted to mediate contrasting evolutionary patterns of positive selection into non-synonymous SNPs across eleven species using TLR7 conservation patterns (evolutionary conserved and class-specific trace residues), where protein sequence differences to the TLR7 receptors of interest record mutation that have passed positive section across the species. In this study, we characterized the Lys609 residue on chTLR7-ECD homodimer interfaces to reflect the current tendency of evolving positive selection to be transfer into a stabilization direction of the R848-agonist/chTLR7-ECDs complex under the phylogenetically variable position across species and we suggest a potential indicator for contrasting evolutionary patterns of both the species TLR-ECDs.

• 한국환경교육학회지:환경교육
• /
• 제12권1호
• /
• pp.172-188
• /
• 1999

Mathematics has been usually recognized as value-neutral and anti-ideological subject, and as a result, it has not dealt with environmental problems clearly. Also, it is not easy to find any environment-related contents in the 7th mathematics curriculum. However, because mathematics is also precious human products and essence, in any ways there is a need to reflect the social issues in the mathematics subject which speak for human mental activities. If this need is admitted to change the mathematics contents to the direction of social issues, environmental problems can stand out and be dealt in the mathematics education. Among the 6 domains in the 7th mathematics curriculum, the environmental problems can be dealt with in the domains of ‘numbers and operation’, ‘letters and formulas’, ‘regularity and function’, ‘chances and statistics’, ‘measurement’ except in the domain of ‘diagrams’. Also, the '문장제들' which takes up a considerable part of mathematics textbooks needs the authentic situation, and thus it will be possible to take environmental situations as mathematical materials. Furthermore, one of the 7th mathematics curriculum is that it suggested further study in each level of each domain, the representative pattern of which is the application of the mathemantics contents to the daily life. With this kind of mathematics further study contents, environmental problems can provide a variety of contents for the further study. From this viewpoint, it can be expected that the contents of environmental education will be increased in the mathematics subject. Under the recognition that the mathematics subject cannot be an exception in considering environmental problems, this study has studied some concrete plans and examples for how the mathematics textbooks based on the 7th educational curriculum can deal with environmental Problems.

• 한국콘텐츠학회논문지
• /
• 제15권11호
• /
• pp.680-685
• /
• 2015

본 연구는 전라남도 K광역시 유아교육기관 6,7 세 유아를 대상으로 행복에 대한 인식을 알아본 것이다. 연구 결과, 첫째, 6, 7세 유아들은 행복에 대한 인식을 자아특성 중 사랑하는 것과 좋은 것과 같은 긍정정서를 가장 중요하게 인식하였다. 7세 유아들은 자아 특성뿐 아니라 가족과 함께 하는 대인관계도 중요하게 인식하였다. 둘째, 6, 7세 유아들은 가장 행복할 때에 대한 인식을 인지 영역 중 놀이 활동을 가장 중요하게 인식하고 있고, 또한 대인관계의 가족을 중요하게 인식하고 있으나, 6에 유아에 비해 7세 유아들이 사랑하는 것과 같은 긍정 정서를 더욱 중요하게 인식하고 있다. 셋째, 행복하려면 어떻게 해야 할 까에 대한 6, 7세 유아의 인식은 대인관계는 부모님 말씀을 잘 들어야 한다는 가족관계와 친구와 사이좋게 놀기와 같은 또래 관계를 중요하게 인식하였으나, 7세 유아가 인지 영역 중 공부를 열심히 해야 한다는 목표를 가장 중요하게 인식하였지만, 6세 유아는 목표를 중요하게 인식하지는 못하였다. 자아 특성은 긍정 정서를 중요하게 인식하였다. 이로써 유아들의 행복에 대한 인식은 긍정 정서가 가장 중요하며, 가족과 함께 하는 대인관계와 또래와 놀이 활동이 중요하다는 것을 알 수 있다. 또한 7세 유아들은 6세 유아에 비해 행복하기 위해 열심히 공부해야 한다는 목표의식을 중요하게 인식하고 있음을 알 수 있다. 이에 유아 행복을 위한 긍정 정서 증진 프로그램의 개발과 가족과 함께 할 수 있는 다양한 부모 참여 프로그램의 필요성을 제언한다. 또한 7세 유아들은 위해 목표 설정을 통한 유아 진로 프로그램 개발의 필요성을 제언한다.

• 한국지구과학회지
• /
• 제22권3호
• /
• pp.248-257
• /
• 2001

7차 과학과 교육과정은 인간중심 교육철학이 도입되었다는 특성을 갖고 있다. 인간중심 교육과정은 학문중심교육과정보다 학습자의 경험을 강조하는 학습자 중심의 교육을 표방하고 있다. 본 연구에서는 우리 나라 과학과 교육과정의 개편 과정에 표출된 배경, 성격 그리고 목표에서 7차 과학과 교육과정의 의의를 찾고 그 과제와 전망을 논의하였다. 7차 과학 교육과정은 학습자의 경험을 강조하는 인간중심 교육과정으로서 구체적인 교육활동이 실생활 소재로 이루어져서 적용되어야함을 강조하고 있다. 이에 관련된 성과를 위해서는 현대과학이 가지는 사회적인 요소를 고려한 과학의 본성에 대한 교사교육이 필요하며, 실생활 맥락을 교육적이고 인식론적인 관점에서 연구하여 과학과 일상생활 맥락의 차이에 대한 적절한 교육적 구명이 요청된다.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2000년도 추계학술대회 논문집
• /
• pp.557-570
• /
• 2000

It is necessary to perform a study on the interrace between a G7 pantograph and a KTX catenary system prior to G7 on-line tests in the Korea High Speed Test Track in order to predict how high current collection quality can be obtained during the on-line tests and check if safety problems shall be caused b)Y the tests or not. According to the simulation results, current collection quality of the G7 pantograph at 350km/h is lower than that of a GPU pantograph at 300km/h, but the contact wire uplifts and average contact forces are within the safe-zone. In addition, the ratio of running speed (350km/h) to safe running. Therefore, the G7 on-line tests at 350km/h in the Korea High Speed Test Track is expected not to cause the safety problem.

• 대한한방내과학회지
• /
• 제28권3호
• /
• pp.608-614
• /
• 2007

Objectives : This study was carried out to investigate anti-proliferative effects on MCF-7 human breast cancer cells of Anemarrhenae Rhizoma (AR) extract. Breast cancer is the most common disease in Korean women. Despite remarkable improvements in treatment strategies against various cancers during the past 40 years. breast cancer still remains as one of the main causes of cancer mortality among women the whole world over. Methods : Be investigated the effects of AR on cytotoxicity of MCF-7 human breast cancer cells in various extract conditions (n-hexane, ethyl acetate, butanol and water fraction). Results : The extract of Anemarrhenae Rhjzoma inhibits the proliferation of MCF-7 cells in a dose dependent manner. Especially. the ethyl acetate fraction of Anemarrhenae Rhizoma showed specific Cytotoxicity on MCF-7 cells. Conclusions : In conclusion. it can be concluded that Anemarrhenae Rhizoma extract has an anti-proliferative effect on MCF-7 human breast cancer cells. Especially. the ethyl acetate fraction is most effective to inhibit proliferation of MCF-7 cells.