• Title/Summary/Keyword: $\mu$ synthesis

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Role of zinc for calcification inhibitor protein in vascular smooth muscle cell plaque formation (혈관 플라그 형성 저해단백질에 대한 아연의 기능)

  • Shin, Mee-Young;Kwun, In-Sook
    • Journal of Nutrition and Health
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    • v.49 no.1
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    • pp.59-62
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    • 2016
  • Purpose: Zinc, a biomineral present within and outside cells, manages various cellular mechanisms. In this study, we examined whether zinc was involved in vascular smooth muscle cell (VSMC) calcification via regulation of calcification inhibitor protein, osteopontin (OPN). Methods: Rat aorta cell line (A7r5 cells) and primary vascular smooth muscle cells (pVSMCs) from rat aorta were cultured with phosphate (1-5 mM) and zinc ($0-15{\mu}M$) as appropriate, along with osteoblasts (MC3T3-E1) as control. The cells were then stained for Ca and P deposition for calcification examination as well as osteopontin expression as calcification inhibitor protein was measured. Results: Both Ca and phosphate deposition increased as the addition of phosphate increased. In the same manner, the expression of osteopontin was upregulated as the addition of phosphate increased in both cell types. When zinc was added, Ca and P deposition decreased in VSMCs, while it increased in osteoblasts. Conclusion: The results imply that zinc may prevent VSMC calcification by stimulating calcification inhibitor protein OPN synthesis in VSMCs.

Synthesis op Daily Streamflow by Multilag Model (다차수모델에 의한 일류량의 추계학적 모의발생)

  • 엄태규;이순택
    • Water for future
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    • v.14 no.1
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    • pp.51-58
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    • 1981
  • This study attempts to examine and estabilish a simulation model from the stochastic analysis of daily streamflow. Daily streamflow records obstained at the main gauging stations along the Han, Nakdong and Geum River were used in the analysis. The following results were abtained. From the analysis of time series of streamflow by the correlogram and spectraal density, The serial component of one-year periodicity, serial correlation and irregular or random component were found. The coefficient of determination R2 of multilag model remaine a plateau at log-two, so that second order mu.ltilag model was Known to fit in the simulation of daily streamflow, Consequently, multilag and recised Markov model of the sewnd order give the best results in simulatin of daily streamflow. But the former generally gives better results than the latter. And theoretical markev model is unfit in the simulation of daily series without modification.

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Design and implementation of the SliM image processor chip (SliM 이미지 프로세서 칩 설계 및 구현)

  • 옹수환;선우명훈
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.33A no.10
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    • pp.186-194
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    • 1996
  • The SliM (sliding memory plane) array processor has been proposed to alleviate disadvantages of existing mesh-connected SIMD(single instruction stream- multiple data streams) array processors, such as the inter-PE(processing element) communication overhead, the data I/O overhead and complicated interconnections. This paper presents the deisgn and implementation of SliM image processor ASIC (application specific integrated circuit) chip consisting of mesh connected 5 X 5 PE. The PE architecture implemented here is quite different from the originally proposed PE. We have performed the front-end design, such as VHDL (VHSIC hardware description language)modeling, logic synthesis and simulation, and have doen the back-end design procedure. The SliM ASIC chip used the VTI 0.8$\mu$m standard cell library (v8r4.4) has 55,255 gates and twenty-five 128 X 9 bit SRAM modules. The chip has the 326.71 X 313.24mil$^{2}$ die size and is packed using the 144 pin MQFP. The chip operates perfectly at 25 MHz and gives 625 MIPS. For performance evaluation, we developed parallel algorithms and the performance results showed improvement compared with existing image processors.

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Photoelectrochemical Water Splitting on a Delafossite CuGaO2 Semiconductor Electrode

  • Lee, Myeongsoon;Kim, Don;Yoon, Yong Tae;Kim, Yeong Il
    • Bulletin of the Korean Chemical Society
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    • v.35 no.11
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    • pp.3261-3266
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    • 2014
  • A pellet of polycrystalline $CuGaO_2$ with a delafossite structure was prepared from $Ga_2O_3$ and CuO by high-temperature solid-state synthesis. The $CuGaO_2$ pellet was a p-type semiconductor for which the electrical conductivity, carrier density, carrier mobility and Seebeck coefficient were $5.34{\times}10^{-2}{\Omega}^{-1}cm^{-1}$, $3.5{\times}10^{20}cm^{-3}$, $9.5{\times}10^{-4}cm^2V^{-1}s^{-1}$ at room temperature, and $+360{\mu}V/K$, respectively. It also exhibited two optical transitions at about 2.7 and 3.6 eV. The photoelectrochemical properties of the $CuGaO_2$ pellet electrode were investigated in aqueous electrolyte solutions. The flat-band potential of this electrode, determined using a Mott-Schottky plot, was +0.18 V vs SCE at pH 4.8 and followed the Nernst equation with respect to pH. Under UV light illumination, a cathodic photocurrent developed, and molecular hydrogen simultaneously evolved on the surface of the electrode due to the direct reduction of water without deposition of any metal catalyst.

Synthesis of Zr-incorporated TiO2 Using a Solvothermal Method and its Photovoltaic Efficiency on Dye-sensitized Solar Cells

  • Kim, Su-Jung;Kang, Mi-Sook
    • Bulletin of the Korean Chemical Society
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    • v.32 no.9
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    • pp.3317-3322
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    • 2011
  • This study examines the photoelectric conversion efficiency of dye-sensitized solar cells (DSSCs) when nanometer-sized Zr (0.1, 0.5, and 1.0 mol %)-$TiO_2$ prepared using a solvothermal method is utilized as the working electrode material. The particle sizes observe in the transmission electron microscopy (TEM) images are < 30 nm in all samples. The absorption band is slightly broadened at the tail for the 0.1 mol % Zr-$TiO_2$, and the intensity of the photoluminescence (PL) curves of the Zr-incorporated $TiO_2$ is significantly smaller than that of the pure $TiO_2$. Compared to that using pure $TiO_2$, the energy conversion efficiency is enhanced considerably by the application of Zr-$TiO_2$ in the DSSCs to approximately 6.17% for 0.5 mol % Zr-$TiO_2$ with the N719 dye (10.0 ${\mu}m$ film thickness and 5.0 mm ${\times}$ 5.0 mm cell area) under 100 mW/$cm^2$ of simulated sunlight.

Antimicrobial Flavonoid, 3,6-Dihydroxyflavone, Have Dual Inhibitory Activity against KAS III and KAS I

  • Lee, Jee-Young;Lee, Eun-Jung;Jeong, Ki-Woong;Kim, Yang-Mee
    • Bulletin of the Korean Chemical Society
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    • v.32 no.9
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    • pp.3219-3222
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    • 2011
  • Three types of ${\beta}$-ketoacyl acyl carrier protein synthase (KAS) are important for overcoming the bacterial resistance problem. Recently, we reported the discovery of a antimicrobial flavonoid, YKAF01 (3,6-dihydroxyflavone), which exhibits antibacterial activity against Gram-positive bacteria through inhibition of ${\beta}$-ketoacyl acyl carrier protein synthase III (KAS III). In this report, we suggested that YKAF01 can be an inhibitor ${\beta}$-ketoacyl acyl carrier protein synthase I (KAS I) with dual inhibitory activity for KAS I as well as KAS III. KAS I is related to the elongation of unsaturated fatty acids in bacterial fatty acid synthesis and can be a good therapeutic target of designing novel antibiotics. We performed docking study of Escherichia coli KAS I (ecKAS I) and YKAF01, and determined their binding model. YKAF01 binds to KAS I with high binding affinity ($2.12{\times}10^6$) and exhibited an antimicrobial activity against the multidrug-resistant E. coli with minimal inhibitory concentration (MIC) value of 512 ${\mu}g$/mL. Further optimization of this compound will be carried out to improve its antimicrobial activity and membrane permeability against bacterial cell membrane.

Synthesis of NaY(WO4)2:Ho3+/Yb3+ Phosphors via The Microwave-Modified Sol-Gel Route and Their Upconversion Photoluminescence Properties

  • Lim, Chang Sung
    • Journal of the Korean Ceramic Society
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    • v.52 no.1
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    • pp.66-71
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    • 2015
  • $NaY_{1-x}(WO_4)_2:Ho^{3+}/Yb^{3+}$ phosphors with doping concentrations of $Ho^{3+}$ and $Yb^{3+}$ ($x=Ho^{3+}+Yb^{3+}$, $Ho^{3+}=0.05$, 0.1, 0.2, and $Yb^{3+}=0.2$, 0.45) were successfully synthesized via the cyclic microwave-modified sol-gel route; their upconversion properties were investigated. Well-crystallized particles showed a fine and homogeneous morphology with particle sizes of $2-5{\mu}m$. Under excitation at 980 nm, the synthesized particles exhibited yellow emissions based on a strong 550-nm emission band in the green region and a very strong 655-nm emission band in the red region. The Raman spectra of the doped particles indicated the domination of strong peaks at higher and lower frequencies induced by the incorporation of the $Ho^{3+}$ and $Yb^{3+}$ elements into the $Y^{3+}$ sites in the crystal lattice, which resulted in unit cell shrinkage that accompanied a new phase formation of the $WO_{4-x}$ group.

A Systematical Design of ADSL POTS Splitter Using Passive Devices (수동 소자를 이용한 ADSL POTS Splitter의 체계적인 설계)

  • 박지만;김진태;소운섭
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.6A
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    • pp.913-919
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    • 1999
  • A systematic synthesis process is presented for the design of ADSL POTS splitters. It consists of a low-pass filter formed by a single-ended inductor, balanced inductor, and balance tightly coupled transformer. This three low-pass filters has been simulation. Simulation results show agreement of frequency characteristics. Therefore, POTS splitters using a commercial balance tightly coupled transformer are designed for the applications of ADSL system. The experimental results show that POTS splitter in the ADSL system has ripple decibel of less than $\pm$0.5 dB over a frequency range from 0.2 kHz to 3.4 kHz(or an audio band frequency) and delay distortion of less than 130 $mutextrm{s}$ over a frequency range from 0.6 kHz to 3.2 kHz.

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Characteristics of PZT Powders Synthesized by Hydrothermal Process (수열합성법으로 제조된 PZT 분말의 특성)

  • Yang, Beom-Seok;Lee, Huk-Hee;Won, Chang-Whan
    • Journal of the Korean Ceramic Society
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    • v.42 no.7 s.278
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    • pp.516-520
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    • 2005
  • Conditions for formation of perovskite Pb(Zr$_{0.52}$Ti$_{0.48}$)O$_{3}$ phase by the hydrothermal synthesis are investigated. Pb(Zr$_{0.52}$ Ti$_{0.48}$)O$_{3}$ ceramics were synthesized by hydrothermal process above 180$^{\circ}C$ for 2 h reaction using 5$\~$30 M KOH solution as a mineralizer. Particle size increases in proportion to the mineralizer concentration. As a result of EOX analysis, PZT powders synthesized using 50 M of KOH as a mineralizer were considered as 2.42 mol$\%$ K doped-PZT powders. And 2.42 mol$\%$ K doped-PZT has much higher mechanical quality factor than undoped PZT ceramics. The sintering properties showed 7.987 g/cm$^{3}$ of sintered density and 3$\~$4 $\mu$m of grain size.

Effect of Fe2+/Fe3+ Molar Ratio on the Synthesized Magnetic Black Pigment by Hydrothermal Method (수열합성법으로 제조한 흑색 자성안료의 Fe2+/Fe3+ 몰비에 따른 특성)

  • Jung, Myung-Ho;Jang, Gun-Eik
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.30 no.12
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    • pp.812-816
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    • 2017
  • $Fe_3O_4$ was prepared on the $TiO_2-coated$ natural mica substrate. The natural mica has an average particle size of $22{\mu}m$. The substrate was coated on $TiO_2$ thin films using hydrothermal synthesis at pH 1.5-2.5 at $75^{\circ}C$. The Fe precursor solution was prepared by mixing $FeSO_4$ (for $Fe^{2+}$ ion) and $FeCl_3$ (for $Fe^{3+}$ ions) with different molar ratios such as 1/2, 1/1, 2/1, 3/0, and $Fe_3O_4$ only. X-ray diffraction analysis shows that the crystal structure depends on the $FeCl_3-to-FeSO_4$ molar ratio. $Fe_3O_4$ crystal phase could be obtained at higher $FeSO_4$ contents.