• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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• pp.327-327
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• 1994

본 연구에서는 간손상에 대한 해독제의 연구 및 안전성 평가연구로서 H$_2$-rcccptor길항제와 한방에서 건위역으로 이용되는 생약추출물 (생강, 정향 및 후박나무의 수피추출물, 강활, 시호, 토복령 및 금은화)이 화합물로 유발된 간독성에 미치는 효과를 고찰하였다. 또한 식물의 2차 대사산물로서 식품, 의약품 및 화장품 향신료 등의 첨가제로 이용되는 monotcrpcnoids중 $\alpha$-pinene, limonenc, gcraniol 및 cincol 이 phase II 효소계중 glutathione S-transferase(GST)의 class alpha 및 mu family계 효소와 microsomal cpoxidc hydrolase(mEH)의 발현에 미치는 영향을 관찰하였다.

• 한국환경과학회지
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• 제31권11호
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• pp.901-910
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• 2022

The aim of this study was to investigate the amount (i.e., retention volume) and chemical composition of Natural volatile organic compounds (NVOCs) across different sites in a temperate forest. The three forest sites that were considered include riparian zones (site 1), streams (site 2), and densely-canopied areas (site 3). From May to October 2021, a mini pump was used to measure the collected NVOCs. These measurements were conducted once a month, from 10:30 am to 11:30 am; these times encompass peak visitation times. In the tree layers of the site 1 and 2, Quercus acuta was dominant, whereas Camellia japonica dominated their subtree layers. On the other hand, the tree layer of site 3 was dominated by Castanopsis sieboldii, whereas Camellia japonica dominated its subtree layer. The retention volume and chemical composition of NVOCs was as follows: benzaldehyde (107.528ppm), α-pinene (37.868ppm), linalool (16.258ppm), eucalyptol (14.818ppm), and sabinene hydrate (14.679ppm). In particular, the retention volume of benzaldehyde decreased as temperature increased. In contrast, the retention volume of α-pinene increased as the temperature increased. The differences in forest topography across the studies sites were in the following order: riparian area> forest area> stream area.

• 한국대기환경학회:학술대회논문집
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• 한국대기환경학회 2005년도 추계학술대회 논문집
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• pp.468-469
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• 2005

• 한국대기환경학회:학술대회논문집
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• 한국대기환경학회 2007년도 추계학술대회 논문집
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• pp.154-155
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• 2007

• Asian-Australasian Journal of Animal Sciences
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• 제29권7호
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• pp.952-959
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• 2016

The objective of this study was to investigate the effects of 11 active compounds of essential oils (ACEO) on rumen fermentation characteristics and methane production. Two trials were conducted. In trial 1, ACEO (eugenol, carvacrol, citral, limonene, 1,4-cineole, p-cymene, linalool, bornyl acetate, ${\alpha}$-pinene, and ${\beta}$-pinene) at a dose of $1,000{\mu}L/L$ were incubated for 24 h in diluted rumen fluid with a 70:30 forage:concentrate substrate (16.2% crude protein; 36.6% neutral detergent fiber). Three fistulated Holstein cows were used as donors of rumen fluid. The reduction in methane production was observed with nine ACEO (up to 86% reduction) compared with the control (p<0.05). Among these, only limonene, 1,4-cineole, bornyl acetate, and ${\alpha}$-pinene did not inhibit volatile fatty acid (VFA) production, and only bornyl acetate produced less methane per mol of VFA compared with the control (p<0.05). In a subsequent trial, the effects on rumen fermentation and methane production of two concentrations (500 and $2,000{\mu}L/L$) of bornyl acetate, the most promising ACEO from the first trial, were evaluated using the same in vitro incubation method that was used in the first trial. In trial 2, monensin was used as a positive control. Both doses of bornyl acetate decreased (p<0.05) methane production and did not inhibit VFA production. Positive effects of bornyl acetate on methane and VFA production were more pronounced than the effects of monensin. These results confirm the ability of bornyl acetate to decrease methane production, which may help to improve the efficiency of energy use in the rumen.

• 한국대기환경학회지
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• 제22권1호
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• pp.145-151
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• 2006

As the concerns about indoor air quality (IAQ) increase in recent years, lots of research works are under way to investigate the influence of volatile organic compounds (VOCs) emitted from building products on the IAQ. One of the regulations for the IAQ is the level of total VOCs (TVOCs) from building products, assuming that the TVOCs are suspected to cause many health problems such as skin irritation, asthma, and allergy. However, the presence of biogenic VOCs, or natural VOCs (NVOCs) is believed to be beneficial to human health. Therefore, this study attempted to investigate chemical species and the NVOCs compositions of solid lumbers from different wood species. It was found that major VOC components were monoterpenes such as $\alpha$-pinene, $\beta$-pinene, d-limonene, camphene, $\alpha$-terpinene, $\gamma$-terpinene etc.

• 약학회지
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• 제49권4호
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• pp.312-316
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• 2005

To develop a new natural antibiotics from Koran plant resources for dealing with the current situation regarding the rapid increase in antibiotic-resistant pathogen, the in vitro inhibitory activities of essential oils from the young leaves of Glehnia littoralis (Umbelliferae) as well as its main constituents were evaluated against susceptible and resistant species of Streptococcus pneumoniae. The essential oil fraction of G. littoralis and its main components, $\alpha-and\;\beta-pinene$, exhibited significant inhibitory activities against the antibiotic-susceptible and resistant strains of S. pneumoniae, with MICs (minimum inhibiting concentrations) ranging from 4.0mg/ml to 16mg/ml. No remarkable differences were shown between the susceptible and resistant strains. Moreover, the disk diffusion test disclosed that these inhibitory activities were dose­dependent. Furthermore, data from the checkerboard titer test with FICIs (fractional inhibiting concentration indices) from 0.15 to 0.28 indicated synergisms between norfloxacin and $\alpha-or\;{\beta}-pinene$ in activity against S. pneumoniae KCCM49629 and S. pneumoniae CCARM4059.

• 생약학회지
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• 제43권4호
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• pp.291-296
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• 2012

The dried roots of Angelica decursiva and Peucedanum praeruptorum are registered as the official sources for the drug 'Junho' in Korean Herbal Pharmacopoeia. In this study the essential oils were extracted from the roots of the two plants by steam distillation. Their compositions and the biological activities were compared. As the results of GC and GC-MS analysis, forty one and thirty five compounds were identified in the essential oils of Angelica decursiva and Peucedanum praeruptorum, respectively. Both of the two essential oils contained ${\alpha}$-pinene as the most abundant component. They showed similar significant antioxidant activities in DPPH scavenging assay, and reducing power test. Their dose dependent inhibitions of the nitrosamine formation were identified in experiment using BHA as control. In MTT test of three cancer cell lines, HeLa, MCF-7 and SK-Hep-1, the essential oil from A. decursiva showed stronger activities than that of P. praeruptorum and their common main component, ${\alpha}$-pinene.

• 한국토양비료학회지
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• 제44권6호
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• pp.1226-1231
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• 2011

The biogenic emission of the atmospheric volatile organic compounds (VOCs) from the forests is dominated by monoterpenes. This study investigated the changes in the concentration of monoterpenes distributed in various types of forest near the Gangwon Nature Environment Research Park, Hongcheon, Gangwon Province, Korea. Samples were collected from the three sites of different types of forest, including coniferous, broad-leaved and mixed forests. Additionally, the seasonal and daily changes of monoterpene compounds were monitored. Our results found the several types of monoterpene such as ${\alpha}$-pinene, ${\beta}$-pinene, camphene, d-limonene, p-cymene and ${\alpha}$-terpinene. The highest total concentration of terpene compounds was observed in the coniferous forest. For the summer season, the total concentration of terpene compounds was highest in coniferous and mixed forests, and that was also highest in broad-leaved forest for the autumn.

• Journal of the Korean Wood Science and Technology
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• 제45권6호
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• pp.682-688
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• 2017

Fresh japanese anise (Illicium anisatum L.) tree leaves were collected and ground after drying. The essential oils of the leaves were analyzed by gas chromatography-mass spectrometry (GC-MS) using headspace (HS) and solid phase-microextra (SPME) methods. Volatile components of the leaves were identified 21 and 65 components in HS and SPME, respectively. The main components of the essential oils obtained by HS method were eucalyptol (36.7%), (+)-sabinene (15.61%), ${\delta}$-3-carene (6.87%), ${\alpha}$-pinene (6.07%), ${\gamma}$-terpinen (5.72%), ${\alpha}$-limonene (5.26%), ${\beta}$-myrcene (4.13%), ${\alpha}$-terpinene (4.04%) and ${\beta}$-pinene (3.73%). The other components were less than 3.5%. SPME method also showed that eucalyptol (17.88%) was main. The other were 5-allyl-1-methoxy-2 (13.29%), caryophyllene (6.09%), (+)-sabinene (5.60%), ${\alpha}$-ocimene (4.89%) and ${\beta}$-myrcene (3.73%), and the rest were less amounts than 3.5%. This work indicated that many more volatile components were isolated, comparing to the previous literature data and that SPME method was much more effective than HS method in the analysis of the volatile components.