• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.45-53
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• 2016

This study examined pruritus to provide the data based on burn patient pruritus. A self-report questionnaire survey was conducted among ninety five burn survivors, who were over 18 years of age with admission periods longer than two weeks. The results indicated that the average burn range was $18.95{\pm}17.10%$, severity was $48.83{\pm}23.96$, and distress was $46.42{\pm}25.80$. A significant difference in pruritus consequences was observed according to frequency. The patients consistently experienced pruritus, even if it happened less often, difficulty in falling asleep (F=4.817, p=.004), poor mood (F= 5.955, p=.015)), and loss of concentration (F=6.483, p<.000). A significant difference in the pruritus consequences according to duration was observed, lasting for 30 minutes for all groups, more than the population and less than 30 minutes, difficulty in falling asleep (F=7.452, p<.000), poor mood (F=3.655, p<.015), and loss of concentration (F=12.564, p<.000). The frequency, duration (r=.29, p=.004), severity (r=.45, p<.000), distress (r=.44, p<.000), and consequences of pruritus in burn patients (r=.29, p=.004) showed a positive correlation. The results of this study could be used as a base material for the care of burn patients experiencing pruritus.

• Bulletin of the Korean Chemical Society
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• v.28 no.12
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• pp.2449-2453
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• 2007

L-[18F]FMAU ([18F]1b) was prepared from the precursor 2-O-[(trifluoromethyl)-sulfonyl]-1,3,5-tri-Obenzoyl- α-L-ribofuranose, by coupling the radioactive fluoro-sugar with the corresponding silylated thymine in 4 steps. The final products, including the α and β anomers, were purified using reverse phase HPLC with an appropriate solvent (5% CH3CN/H2O) at a flow rate of 3.0 mL/min. The total elapsed time of synthesis was about 180-200 min from EOB. The α/β anomeric ratio of the compounds was about 1:9, and the radiochemical purity of the product (β-form) was >98% with decay-corrected yields of 25-35%. All radioactive samples were confirmed using co-injection with pure non-radioactive analogues in every step. In the cellular uptake in vitro test of herpes simplex virus-thymidine kinase (HSV1-TK) gene expressed cells, the percent uptake of injected dose (%ID) of L- and D-FMAU was 37.28 and 65.86, respectively after 240 min incubation. However, the relative uptake (MCA-TK/MCA cellular uptake ratio) of L-FMAU was higher than that of D-FMAU (%ID of L-FMAU, 0.36 and D-FMAU, 0.93 after 240 min incubation in MCA cells). This means that L-FMAU will show better specific HSV1-TK gene expressed cell uptake for selective HSV1-TK gene imaging.

• The Korean journal of internal medicine
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• v.39 no.2
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• pp.327-337
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• 2024

Background/Aims: The prognostic significance of ¹⁸F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential ¹⁸F-FDG PET/CT during frontline chemotherapy of patients with PTCLs. Methods: In total, 143 patients with newly diagnosed PTCLs were included. Sequential ¹⁸F-FDG PET/CTs were performed at the time of diagnosis, during chemotherapy, and at the end of chemotherapy. The baseline total metabolic tumor volume (TMTV) was calculated using the the standard uptake value with a threshold method of 2.5. Results: A baseline TMTV of 457.0 cm³ was used to categorize patients into high and low TMTV groups. Patients with a high TMTV had shorter progression-free survival (PFS) and overall survival (OS) than those with a low TMTV (PFS, 9.8 vs. 26.5 mo, p = 0.043; OS, 18.9 vs. 71.2 mo, p = 0.004). The interim ¹⁸F-FDG PET/CT response score was recorded as 1, 2-3, and 4-5 according to the Deauville criteria. The PFS and OS showed significant differences according to the interim ¹⁸F-FDG PET/CT response score (PFS, 120.7 vs. 34.1 vs. 5.1 mo, p < 0.001; OS, not reached vs. 61.1 mo vs. 12.1 mo, p < 0.001). Conclusions: The interim PET/CT response based on visual assessment predicts disease progression and survival outcome in PTCLs. A high baseline TMTV is associated with a poor response to anthracycline-based chemotherapy in PTCLs. However, TMTV was not an independent predictor for PFS in the multivariate analysis.

• The Korean Journal of Nuclear Medicine Technology
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• v.25 no.2
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• pp.48-54
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• 2021

Purpose In ¹⁸F-FDG PET/CT, the absorption of ¹⁸F-FDG due to the activation of Brown Adipose Tissue (BAT) greatly interferes with the discrimination of lymph node malignant metastasis. Warming the patient's body temperature before and after injection of ¹⁸F-FDG to prevent FDG absorption by BAT is a safe and non-pharmacological approach. The purpose of this study was to identify and select patients with a high potential for BAT activation in advance, and to investigate whether BAT can inhibit FDG absorption when the body temperature is raised for a short time by directly applying heat to the target patient. Materials and Methods Among the patients who underwent ¹⁸F-FDG PET/CT at the National Cancer Center from January 2020 to December 2020, 825 female patients (415 in the thermal group, 410 in the non-thermal group) under 50 years old were included. The thermal group was administered heat for 10 minutes before injection of ¹⁸F-FDG. For statistical analysis, the Z test comparing the ratios between the two groups was used, and logistic regression analysis was performed to correct for important variables (BMI, outdoor temperature, blood sugar) according to the results of the previous retrospective study. Results Among 825 patients, 19 patients with BAT activated (Thermal group: 5(1.2%), Non-thermal group: 14(3.41%)) accounted for 2.3% of the total. As a result of performing the Z test to compare the ratios between the two groups, the activation of BAT in the thermal group was significantly decreased (P=0.034). In the univariate logistic regression analysis, the activation of BAT was also decreased in the thermal group (OR: 0.34, P<0.05). In the multivariate results, BAT activation increased in patients younger than 45 years old (OR: 4.46, P<0.05) and outdoor temperature less than 13.2 degrees (OR: 9.97, P<0.05). BAT activation tended to decrease in the thermal group, but there was no significant difference (OR: 0.37, P=0.066). Conclusion We confirmed that the activation of BAT tends to decrease by 62.5% in the group subjected to the thermal method, and it will be of great help in preventing FDG absorption of BAT more effectively in the future.

• Korean Journal Plant Pathology
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• v.11 no.4
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• pp.324-329
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• 1995

Severe Fusarium wilt of tomato was observed in greenhouses in Sedo, chungnam and Sandae, Kyeongbuk from march to May 1993. Among the 20 isolates of Fusarium oxysporum isolated from wilted tomato plants and their rhisoplane or rhizosphere, 18 isolates were pathogenic to tomato. All of the pathogenic isolates were identified as F. oxysporum f. sp. lycopersici; they were pathogenic only to tomato and not pathogenic to red pepper, potato and egg-plant. The isolates of F. oxysporum f. sp. lycopersici used in this study could be divided into 2 races according to their pathogenicity to eight differential varieties of tomato. Of 10 isolates tested, 6 were classified as race 1, while 4, as race 2.

• Geomechanics and Engineering
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• v.37 no.2
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• pp.123-133
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• 2024

This study investigates the effects of loading frequency (f) and specimen size on the liquefaction resistance of clean sand. A series of cyclic direct simple shear tests were conducted on Jumunjin sand with varying consolidated relative densities (40% and 80%), f values (0.05, 0.10, and 0.20 Hz), and diameter to height (D/H) ratios (3.63, 3.18, 2.82, and 2.54). The results demonstrated the significant influence of f and D/H ratio on the number of cycles to liquefaction (N_cyc-liq) and the cyclic resistance ratio (CRR₁₅). It was observed that increasing f linearly increased N_cyc-liq. Increasing the specimen height also led to higher N_cyc-liq values irrespective of the f or relative density. Moreover, a positive correlation between CRR₁₅ and f indicated that higher f yielded higher CRR₁₅. This relationship was more pronounced in dense sand than in loose sand. Specimen height also significantly affected CRR₁₅, with increasing the specimen height resulting in higher CRR₁₅ values. Furthermore, the effect of f on CRR₁₅ was less significant compared to the influence of specimen height. The effect of f on the normalized cyclic resistance ratio (NCRR) was relatively negligible for loose sand but more substantial for dense sand depending on the D/H ratio. Data analysis revealed that the NCRR generally decreases as the D/H ratio increases. An interpolation formula was provided to calculate the NCRR based on the D/H ratio regardless of the f and relative density.

• Korean Chemical Engineering Research
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• v.56 no.4
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• pp.447-452
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• 2018

Titanium nanotubes (TNT) of various lengths ranging from $0.34^{\circ}C$ to a maximum of $8.9^{\circ}C$ were prepared by anodizing a titanium metal sheet in an electrolyte containing fluorine ion ($F^-$) of HF, NaF and $NH_4F$. When TNT prepared by anodizing was calcined at $450^{\circ}C$, anatase crystals with photo activity were formed. The TNT-based dye-sensitized solar cell (DSSC) showed a maximum conversion efficiency of 4.71% when the TNT length was $2.5{\mu}m$. This value was about 18% higher than photo conversion efficiency of the FTO-based DSSC coated with titania paste. And the short circuit current density ($J_{sc}$) of the TNT-DSSC was $9.74mA/cm^2$, which was about 35% higher than the $7.19mA/cm^2$ of FTO-DSSC. The reason for the higher conversion efficiency of TNT-DSSC solar cells is that photoelectrons generated from dyes are rapidly transferred to the electrode surface through TNT, and the recombination of photoelectrons and dyes is suppressed.

• Korean Journal of Crystallography
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• v.6 no.1
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• pp.27-35
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• 1995

The crystal structure of 1-tert-butoxycarbonyl-4-[N-(tert-butoxycarbonyl)-N-(ethoxycarbonylmethyl)amino]-3-phenylsulfonylpyrrolidind [C24H36O8N2S] has been from single crystal x-ray diffraction study ; C24H36O8N2S triclinic, p1, a=11.363(8)Å, b=11.589(6)Å, c=11.013(10)Å,α=95.32(6)°,β=98.64(7)°,γ=79.57(5)°,V=1406.8(18)Å3, t=293K, Z=2, CuKα(λ=1.5418Å). The molecular structure was solved by diredt method and refined by full-matrix least squares to a final R=9.78% for 3621 unique observed [F≥4σ(F)] reflections and 703 paramenters.

• Journal of the Korean Wood Science and Technology
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• v.51 no.2
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• pp.109-132
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• 2023

The objective of this study was to reveal the impact of thinning and pruning regimes on the physical and mechanical properties of clonal teak wood planted in Java. In this study, a 15-year-old clonal teak plantation was carried out and the obtained data were evaluated with analysis of variance (ANOVA). The results showed that different thinning intensities had a significant impact on the alteration of heartwood volume development (F = 25.63; p < 0.0001). Meanwhile, the impact of different thinning treatments in several physical properties depends on the pruning treatment levels [moisture content (F= 12.18, p < 0.0001); tangential shrinkage (F = 15.60, p < 0.0001); T/R ratio (F = 7.17, p < 0.0001); and volumetric shrinkage (F = 10.81, p < 0.0001)]. However, different thinning intensities had no significant impact on wood basic density alteration (F = 0.72, p = 0.486), while pruning intensities affect the differences between radial (F = 3.52, p = 0.030) and volumetric shrinkage (F = 3.13, p = 0.044). In mechanical properties, thinning intensity levels did not promote any significant differences [modulus of elasticity (F = 1.41, p = 0.248); modulus of rupture (F = 0.94, p = 0.392); compressive strength parallel to grain (F = 0.21, p = 0.813); and compressive strength perpendicular to the grain (F = 0.41, p = 0.669)]. Meanwhile, different pruning treatments and combination treatments were not significantly altered all mechanical properties. These results indicated that the thinning and pruning regimes can enhance the mechanical properties without having a serious alteration in the physical properties of clonal teak wood.

• Applied Chemistry for Engineering
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• v.18 no.4
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• pp.326-329
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• 2007

2-Arylidenehydrazinyl-4-arylthiazole derivatives (9a-f) were prepared by the in situ formation of ${\beta}$-cyclodextrin complex of 2,4'-dibromoacetophenone (8) in water followed by the addition of arylidenethiosemicarbazones (7a-f) in 70~88% yield. The structures of the compounds 9a-f were elucidated by IR and $^1H-NMR$ spectral data. The role of ${\beta}$-cyclodextrin appears to activate the compound 7 and 8 and promote the reaction to complete in reduced reaction time.