• Parasites, Hosts and Diseases
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• v.55 no.1
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• pp.61-64
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• 2017

We described a human case of zoonotic dog tapeworm, Dipylidium caninum (Eucestoda: Dilepidiidae), rarely occurring in China. The mother of a 17 month-old boy noted the appearance of small white and active worms over a month period in her son's feces, but the boy was asymptomatic except mild diarrhea. We observed 3 tapeworm proglottids resembling cucumber seeds in his stool sample. Microscopically, each proglottid had 2 genital pores, 1 on each lateral edge, and numerous egg capsules in the uterus. The patient was successfully treated with a single oral dose of praziquantel. Adult worms were recovered in the diarrheic stool after praziquantel treatment and purgation. His family had household pet dogs for several years, and he might have acquired the infection by ingestion of infected fleas of his pet dogs. A history of dog or cat pets and flea bites may be important clues to diagnosis of D. caninum infection. The infected pets should also be treated.

• Macromolecular Research
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• v.10 no.2
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• pp.122-126
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• 2002

A molecularly imprinted polymer (MIP) having both amidine and imidazole functional groups in the active site has been prepared using p-nitrophenyl phosphate as a transition state analogue (TSA). The imprinted polymer MIP with amidine and imidazole found to have the highest hydrolysis activity compared with other MIPs with either amidine or imidazole groups only. It is postulated a cooperative effect between amidine and imidazole in the hydrolysis of p-nitrophenyl methyl carbonate (NPMC) as a substrate when both groups were arranged in proximity by molecular imprinting. The rate enhancement of the hydrolysis by MIP was 60 folds over the uncatalyzed solution reaction and two folds compared with the control non-imprinted polymer CPI having both functional groups. The enzyme-mimetic catalytic hydrolysis of p-nitrophenyl acetate by MIP was evaluated in buffer at pH 7.0 with $K_{m}$ of 1.06 mM and $k_{cat}$ of 0.137 $h^{-1}$ . . .

• Journal of Plant Biotechnology
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• v.36 no.2
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• pp.179-183
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• 2009

To understand the effect of reactive oxygen species (ROS) on floral senescence in Hibiscus syriacus L., we have investigated change in relative water potential, malondialdehyde (MDA) content, H_2O_2 content and the activity of antioxidative enzymes in the petals during flower opening and senescence. Hibiscus flowers were achieved full bloom at early morning and started to in-rolling and showed petal in-rolling over than 50% at 24 h and 36 h after full bloom, respectively. The flower was a decrease in fresh weight by 30% and showed water loss with floral senescence. MDA content and activity of antioxidative enzymes such as APX, GR and CAT were showed no significant change until 36 h after full bloom. In the flower 48 h after full bloom that showed complete petal in-rolling and wilting, however, activity of antioxidative enzymes and H_2O_2 content was greatly increased as compared with 0 h after full bloom. These results suggest that reactive oxygen species are related to accelerating the later senescence more than inducing the early senescence during Hibiscus flower senescence.

• The Korean Journal of Physiology
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• v.13 no.1_2
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• pp.35-40
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• 1979

The present study was undertaken to investigate effect of water extracts of the mulberry leaves (MWE) on arterial blood pressure and respiration in cats. And also studied were depressor responses to intravenously administered MWE in the animals pretreated separately with atropine(2.5 mg/kg), propranolol(2 mg/kg), dibenamine (15 mg/kg), and hexamethonium (1.5 mg/kg) in order to find out the mechanism of depressor activity of MWE. The results obtained were as follows; 1) Following intravenous administration of 0.25 ml/kg and 0.5 ml/kg of MWE into the cat the maximum depressor responses observed were $60.2{\pm}2.3\;mmHg$ and $72.3{\pm}1.7\;mmHg$ respectively. 2) Since depressor responses to intravenously administered MWE were partially inhibited by hexamethonium and markedly by atropine, it is strongly suggested that depressor activity of MWE mainly results from its vagal effects. 3) After administration of MWE respiratory rate was invariably increased following a short period of apnea.

• Korean Journal of Veterinary Service
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• v.37 no.4
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• pp.281-290
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• 2014

The purpose of this study was to determine the zoonotic diseases of stray dog and cat in Gwangju, Korea. We chose randomly 300 samples which is 265, dogs and 35, cats in the public animal shelter from March to August of 2013. The animals' blood biochemistry values measured, and the out of normal values were 49.7% GOT, 36.3% GPT, and 78.0% GGT. The tested items were Dirofilaria immitis, Toxoplasma gondii, Brucella canis, Rabies virus. The positive results were 10% Dirofilaria immitis, 6.3% Toxoplasma gondii (antibody detected), 10% Rabies (antibody detected) but 0.0% in B. canis. The stray animals' antibody antigen positivity take effect high from Mar.-May. Therefore, we propose that those diseases should be monitering and vaccinating in Korea.

• Journal of the Ergonomics Society of Korea
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• v.28 no.4
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• pp.83-89
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• 2009

This study was conducted to assess exposure to musculoskeletal disorders risk factors in the cooking & housekeeping jobs in hotel work. PATH (posture, activity, tools and handling) method was used for data collection at the 6 hotel settings in different regions across Korea. From 26 workers, a total of 949 PATH observations were obtained. The highest percent time on non-neutral posture was 78% for pinch grip, followed by 74%(wrist deviation), 52%(trunk posture), 37%(shoulder/arm posture), and 30%(neck posture). The highest percent time in the three HAL variables was 47% for HAL-cat2. The percent time of items in relation to both loads with more than 5kg and contact stress was less than 2%. The hotel workers were not exposed to vibration.

• Steel and Composite Structures
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• v.46 no.2
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• pp.153-173
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• 2023

Rectangular concrete-filled steel tubular (RCFST) column, a type of concrete-filled steel tubular (CFST), is widely used in compression members of structures because of its advantages. This paper proposes a robust machine learning-based framework for predicting the ultimate compressive strength of RCFST columns under both concentric and eccentric loading. The gradient boosting neural network (GBNN), an efficient and up-to-date ML algorithm, is utilized for developing a predictive model in the proposed framework. A total of 890 experimental data of RCFST columns, which is categorized into two datasets of concentric and eccentric compression, is carefully collected to serve as training and testing purposes. The accuracy of the proposed model is demonstrated by comparing its performance with seven state-of-the-art machine learning methods including decision tree (DT), random forest (RF), support vector machines (SVM), deep learning (DL), adaptive boosting (AdaBoost), extreme gradient boosting (XGBoost), and categorical gradient boosting (CatBoost). Four available design codes, including the European (EC4), American concrete institute (ACI), American institute of steel construction (AISC), and Australian/New Zealand (AS/NZS) are refereed in another comparison. The results demonstrate that the proposed GBNN method is a robust and powerful approach to obtain the ultimate strength of RCFST columns.

• Journal of Microbiology and Biotechnology
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• v.34 no.7
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• pp.1401-1409
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• 2024

Postbiotics have various functional effects, such as antioxidant, anti-inflammatory, and anti-obesity. Levilactobacillus brevis BK3, the subject of this study, was derived from lactic acid bacteria isolated from Kimchi, a traditional Korean fermented food. The antioxidant activity of BK3 was confirmed through the measurements of 2,2-diphenyl-1-picryl-hydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and total antioxidant capacity (TAC). The wrinkle improvement effect was validated by assessing elastase inhibitory activity and collagenase inhibitory activity. The intracellular activity was confirmed using human keratinocytes (HaCaT) and human fibroblasts (HFF-1). BK3 protects skin cells from oxidative stress induced by H₂O₂ and reduces intracellular reactive oxygen species (ROS) production. In addition, the expressions of the antioxidant genes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were upregulated. Meanwhile, matrix metalloproteinase-1 (MMP-1) and collagen type I alpha 1 (COL1A1), involved in collagen degradation and synthesis, were significantly regulated. These results suggest the possibility of utilizing BK3 as a functional ingredient with antioxidant and wrinkle-improving effects.

• Journal of KIISE
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• v.44 no.12
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• pp.1307-1312
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• 2017

Due to their convergence with state-of-the-art ICT technologies, the complexity and reliability demands of industrial automation systems have been rapidly increasing. In recent years, to cope with these demands, several research works have been carried out to adopt formal methods to the application development cycle at the early design stage. In this paper, we propose an automated code generation framework for industrial automation applications, based on a timed automata model. As a case study, we developed a formal model for a traffic light control system and verified the timing properties described in the specification. We finally demonstrated that the operation of a test-bed based on the auto-generated native code was identical to that of the model specification.

• Bulletin of the Korean Chemical Society
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• v.26 no.9
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• pp.1385-1389
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• 2005

Human hepatitis B virus (HBV) is a pathogen related to the development of liver diseases including chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). However, the efficient methods to suppress HBV replication have not been developed yet. Therefore, we have used RNA interference (RNAi) as a potential tool for the suppression of HBV replication. Here, we designed a 21 nt small intefering dsRNA (siRNA) against hepatitis B virus X (HBx) RNA with 3' overhanging ends derived from T7 promoter. It has been reported that HBV X protein plays an important role in HBV gene expression and viral replication. The suppression of HBx gene expression by the 21 nt siRNA was investigated by Northern blot analysis and chloramphenicol acetyl transferase (CAT) assay. The level of HBx mRNA was decreased by siRNA in a dose-dependent manner. We also found that the 21 nt siRNA inhibited the HBV replication in hepatocellular carcinoma cell.