• Korean Journal of Pharmacognosy
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• v.39 no.4
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• pp.271-289
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• 2008

In the Oriental Medicine field the great three reference books are Hwantienaekyung(黃帝內徑, HJNK), Sihnnongbonchokyung(神農本草經, BCK) and Shanghanlun(SHR). HJNK has been a theory book regarded as a bible of the Oriental Medicine, BCK, a herbal book with 365 species of red letters noticed from Bonchokyungjipjoo(本草經集註) and SHR, very important clinical book with concrete prescriptions for the therapy of patients. Though these books were written by Chinese people ca. 2000 years ago, yet they are no doubt very important and effective ones in these days. Unfortunately they are handed down to all transmitted books for a long times because original ones were destroyed by fire and another troubles. In this study we have tried to extract three common terminological words and common theories from the prescription law by theoretical principles(理法方藥, clinical therapeutic mechanism) acquired through the comparative analysis of these three books. They are qi(氣), cold or heat(寒熱) and yin & yang(陰陽), and their practical basic theories have been evidenced through exterior & interior of body(表裏) and deficiency or exessiveness(虛實) by the heat of Sun. Also we would have realized that Oriental Medicine should be analyzed through various scientific techniques and clinical experiences, and necessarily unified to yin & yang monism from qi theory of the Sun in all human's life cycle(生老病死).

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.637-641
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• 2002

In order to convert the one ryang of Guizhi-tang into the modern weights and measures, herbs whose dose was expressed by number in Treatise on Feverile Disease of Zhongjing were measured actually. The results obtained are as follows. 1. Size of Jujubae fructus in Guizhi-tang is an average and if remove the seed, 12 Jujubae fructuses corresponds to 20g. These weights are the same as Belamcandae Rhizoma, Persicae Semen, Gleditsiae Fructus, Gardeniae Fructus and Armeniacae amarum Semen whose dose was expressed by number in Treatise on Feverile Disease of Zhongjing. If one ryang corresponds to 6.5g, 20g corresponds to three ryang. If one ryang corresponds to 15.6g, 20g corresponds to 1.3 ryang. When herbs were added in Guizhi-tang, the used weights were two more ryang. Almost unit of weights in Formulae of Zhongjing is the constantly multiplied. 2. Half sheng(升) of Pinelliae Rhizomae is 15 Pinelliae Rhizomas and corresponds to two and a half ryang. 14 Pinelliae Rhizomas are contained in 50 mL egg. 3.1 geun(斤), maximal amount of Gypsum Fibrosum and amount of one egg are the same weight supposing one ryang corresponds to 6.5g. 4. 2 ryang of Rhei Radix et Rhizoma is the 6.8 balls(碁子) of baduk and similar as 5-6 balls of baduk of Jisilchijasi-Tang. 5. General dose of Glycyrrhizae Radix is two ryang and 20mL, the size of thumb is 13g. 6. Half geun approaches the 3 flattened spoons. Consequently the presumption that one ryang in Guizhi-tang is 15.6g is wrong. One ryang is assumed as 6.5g.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.2
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• pp.153-166
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• 2013

Yang deficiency pattern is a representative syndrome differentiation. This article is a study on to which categories of modern diseases yang deficiency is assigned by reference to modern clinical papers and the meaning of yang deficiency interpreted with a perspective of Korean Medicine and a modern perspective. Yang deficiency, yang qi deficiency, lack of yang qi and yang qi debilitation are the words found in "Nei Ching" and yang qi can be interpreted as something to warm, drive and arouse. Zhangzhongjing considered recovery or loss of Yang as the key to life in "Shanghanlun". Danxi proposed "Yang being liable to hyperactivity, Yin being insufficient" and emphasized pathological ministerial fire of Yang exuberance rather than physiological ministerial fire of Yang deficiency. Zhangjingyue proposed "Yang not being in excess, Yin being often deficient" and understood growth and decline of yin qi are all led by yang qi and put emphasis on true yin in addition to yang qi. Diseases of yang deficiency pattern are related with decline of metabolic level, hypofunction of internal secretion, disorder of immune function, disorder of automatic nerve system, sympathetic nerve inhibition, metabolic disorder of microelements, increase of cGMP, change of microcirculation, low speed of blood stream, kidney malfunction. Diseases related with kidney are sterility, polycystic ovary syndrome, spinal stenosis, edema, renal failure, IgA nephropathy, erectile dysfunction, nephritis, prostatitis, benign prostatic hyperplasia, decrease of adrenal cortical hormone by nephrotic syndrome, myelodysplastic syndrome. Disease related with heart are heart failure, arrhythmia, cardiomyopathy, atherosclerosis heart disease, hypertension, hyperlipidemia, pulmonary heart disease. Diseases related with spleen are irritable bowel syndrome, ulcerative colitis. Diseases related with liver are hypothyroidism, liver cirrhosis ascites, hepatitis B, chronic hepatitis, hepatic diabetes. Diseases related with lung are allergic rhinitis, cough variant asthma, bronchial asthma, pulmonary emphysema. And diabetes mellitus, metabolic syndrome, aplastic anemia, headache, encephalatrophy, Alzheimer's disease are also related with yang deficiency.

• Journal of Korean Medical classics
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• v.30 no.3
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• pp.109-131
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• 2017

Objectives : The purpose of this paper is to study the origin, mechanism, category of Chest bind with static blood(血結胸), the relation to the syndrome of Heat entering the blood chamber(熱入血室證), and the comparison with Chest bind(結胸). Methods : Sikuquanshu(四庫全書), a comprehensive range of medical books, and Shanghanlun(傷寒論) annotation books were searched by 'Chest bind with static blood' keyword and analyzed. Results & Conclusions : 1. The syndrome of Chest bind with static blood is first brought up by ZhuGong(朱肱) and it can be derived from the syndrome of Heat entering the blood chamber or can be shown in upper middle lower energizer Stagnated Blood Syndrome(上中下焦蓄血證, SBC). Ever since the publication of Shanghanquanshengji(傷寒全生集), its category was expanded and prescriptions for the SBC were used. 2. In comparison, the cause of Chest bind with static blood is associated with blood heat(血熱), largely connected with blood, mental illness appeared, lesions are usually chest and sides, and the cause of Chest bind is associated with intermingled water heat (水熱) or phlegm heat(痰熱), not connected with blood, mental illness not appeared, lesions are from the beneath the heart to lower abdomen. 3. The syndrome of Chest bind with static blood derived from the syndrome of Heat entering the blood chamber can appear along side with the Liver Meridian associated with blood chamber or appear in chest, the syndrome appeared in upper energizer SBC can be shown in the chest due to gravity, the one appeared in middle energizer SBC can be shown in the chest due to the same level, the one appeared in lower energizer SBC can be shown in the chest due to the constitutional predisposition of YangQi(陽氣) uprise.

• The Journal of Korean Medical History
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• v.22 no.1
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• pp.57-67
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• 2009

The results of analyzing "Shanghanlun-Shanghan examples" of Song Dynasty Text and Liuwansu's writings in the pursuit of comprehending his views written in "Fire-Heat" & "Warm disease" -are as follow. 1.He introduced Exterior-Interior Shanghan and Latent in the Winter & recurrent in the Spring Shanghan concept in the Febrile disease pathology as the link and the bifurcation point. His perception on Febrile disease encompassed Shanghan and Febrile disease on the same plane but actually discriminated in the treatment and medication between the two actually. 2.He suggested Febrile disease pathology in the concept of Shanghan and Febrile disease, which is coherent in the formation of interior heat as the result of the invasion of the lung by warm pathogen described in Warm disease Wei, Qi, Ying and Xue Fen Syndrome differentiation. He expanded the concept of esoteric portal 玄府 of "Suwon Tiaojinglun", to that of the omni-present portal & way of Qi's all directions movement, which is in accordance of invasion of upper energizer 上焦 by warm or hot pathogen via mouth and nose as used in Warm disease three-energizer differentiation. 3.He recognized both exterior-interior febrile disease in the context of both exterior-interior contact cause disease. He prescribed pungent-cool exterior releasing medicinal similar to that of exterior-releasing treatment adopted in warm disease. As lily-talc powder百合散 introduced in "Golden chamber synopsis" dispells heat by promoting excretion of urine and defecation, it is regarded as the original formula of later ikwonsan yiyuansan 益元散.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.418-426
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• 2012

Murai Kinzan was a disciple of the great Ko-bang scholar, Yoshimasu Todo(吉益東洞). He was born in a family of doctors, he helped his father's medical works and together made an institution of medical education. He wrote many medical books such as "Yakuchozokuhen(藥徵續編)", "Idonisen'nenganmokuhen(醫道二千年眼目編)" and "Hogyokusantei(方極刪定)". He followed Yoshimasu Todo's theories that "All disease comes from a single poison" and criticized scholars such as Yoshimasu Nangai(吉益南涯) for modifying the theories of his teacher, Yoshimasu Todo. He was also influenced by Kagawa Shuuan(香川修庵) through his father, and learned medicine from Yamawaki Touyou(山脇東洋) through letters. Under the influence of these great scholars, he pursued empirical and practical medicine based on his own experience using "Shanghanlun(傷寒論)" and "Jinguiyaolue(金匱要略)" for reference. In "Yakuchozokuhen" and "Yakuchozokuhenhuroku", Murai Kinzan maintained the main frame of "Yakucho(藥徵)", Yoshimasu Todo's work, discussing in 5 categories. Medicines that are used popularly were written in "Yakucho" and "Yakuchozokuhen", therefore those books were discussed in 5 categories. However, "Yakuchozokuhenhuroku" were discussed only in 1 ~ 3 categories.

• Journal of Korean Medical classics
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• v.28 no.4
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• pp.193-212
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• 2015

Objectives : The purpose of this study is to find the differences of the viewpoints about medicine between Korean and Japanese doctors through analysing the contents of the medical conversation records from the visits of Joseontongshinsa. Methods : The conversations were classified according to the topics and analysed with emphasis on the subject of medical classics. Results : Japanese doctors were skeptical about the application of Huangdineijing(黃帝內經) and the theory of Five Circulation and Six Qi(五運六氣) to clinical treatment while they respected Shanghanlun(傷寒論). They were interested in the bibliography of medical classics, and considered it was important to study the original texts rather than the new editions. The doctors of Joseon valued Huangdineijing highly and accepted the theory of Five Circulation and Six Qi. They mainly used the treatments in Yixuezhengzhuan(醫學正傳), Yixuerumen(醫學入門), Shoushibaoyuan(壽世保元) as therapeutic methods. Conclusions : The conversation records reflect the trend of Korean Medicine in the Joseon Dynasty that Huangdineijing had been mainly studied and the Jin-Yuan(金元) Medicine had been accepted, and the trend of Japanese Medicine in the mid-Edo period that Koho school(古方派) had predominated.

• Journal of Sasang Constitutional Medicine
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• v.10 no.2
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• pp.61-110
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• 1998

1. Purpose : This study is a try for making a historical examinatiom of the symptom, principal medicinal substances and prescription of Soyangin Bisoohan-Pyohan disease. 2. Methods : I have examined the changes of the recognition of symptom and the history of the development of prescription by comparing the exterior syndrome of Soyangin, related prescription and principal medicinal substances quoted in "DongYi-Soose-Bowon" with past original texts and "DongYi Bogam". 3. Results and Conclusion : Lee Je-Ma adopted most of the exterior syndrome of Soyangin from Zhang Zhong-jung's "Shanghanlun". But he adopted only a few medicinal substances for prescription and most of prescriptions written after the Song period. The prescriptions for Soyangin Bisoohan-Pyohan disease are fundamentally composed of medicinal substances to lower yinqi and to eliminate the heat of thoracic part caused acording to the degree of symptom and medicinal substances to strengthen damaged yinqi are added to the prescriptions.

• Journal of Korean Medical classics
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• v.32 no.3
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• pp.131-146
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• 2019

Objectives : The aim of this paper is to study the methodology for effectively analyzing the "Jinguiyaolue" prescriptions using database, and to explore possibilities of applying the data construction and query produced in the process to comparative research with other texts in the future. Methods : Using "Xinbianzhongjingquanshu(新編仲景全書)" as original script, the contents of "Jinguiyaolue" were entered into the database, in which one verse would be separated according to content for individual usage. Also, data with medicinal construction and disease pattern information of the previously constructed "Shanghanlun" database designed for comparison with other texts was applied for comparative analysis. Results : For input and analysis, 6 tables and 12 queries were made and used. Formulas were accessible by using herbal combinations, and applications of these formulas could be assembled for comparison. Formulas were also accessible by using disease pattern combinations, and combinations of herbs and disease pattern together were also applicable. In comparison with other texts, examples and frequency of usage of herbs could be relatively accurately compared, while disease patterns could not easily be compared. Conclusions : Herbal combinations, disease pattern combinations could yield related texts and herb/disease pattern combinations of the prescriptions in the "Jinguiyaolue", which shortened time needed for research among formulas in texts. However, standardization research for disease pattern is necessary for a more accurate comparative study that includes disease pattern information.

• Herbal Formula Science
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• v.30 no.1
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• pp.19-25
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• 2022

Objectives : Huangqintang(⿈芩湯) is a famous herbal prescription in the Traditional Korean Medicine (e.g. Shanghanlun) to treat various chronic disease such as neurological disease and digestive system disease. Its components include Scutellariae Radix(⿈芩), Paeonia lactiflora(芍藥), Glycyrrhizae Radix et Rhizoma(⽢草), Zizyphi Fructus(⼤棗). Methods : In this study, we standardize the name, composition and medical uses of Huangqintang by literature studying and paper searching. Based on the comparison between oriental medicine and modern medicine pharmacology, we linked the medical uses of Huangqintang to Korean Standard Classification of Diseases (KCD). Results and Conclusion : The name of the prescription is unified into "Huangqintang", and its composition ratio between Scutellariae Radix, Paeonia lactiflora, Glycyrrhizae Radix et Rhizoma, and Zizyphi Fructus is 3:2:2:3. Huangqintang is used for enteritis diseases due to its antipyretic and antinflammatory effects. Its medical application was relatied with 'A'code, 'C'code, and 'K'code as indicated by KCD. By standardizing the mixed conceptions of Huangqintang, this review will facilitate the coding of Huangqintang prescription. Therefore, it will make Huangqintang prescription more useful in clinics.