The building sector has seen a huge increase in the use of lightweight concrete recently, which might result in saving in both cost and time. As a result, the study has been done on various types of concrete, including lightweight (LC), heavyweight (HC), and ordinary concrete (OC), to understand how they react to earthquake loads. The comparisons between their responses have also been taken into account in order to acquire the optimal reaction for various materials in building work. The findings demonstrate that LWC building models are more earthquake-resistant than the other varieties due to the reduction in building weight which can be a curial factor in the resistance of earthquake forces. Another crucial factor that was taken into study is the combination of various types of concrete [HC, LC, and OC] in the structural components. On the other hand, the bending moments and shear forces of LC had reduced to 17% and 19%, respectively, when compared to OC. Otherwise, the bending moment and shear force demand responses in the HC model reach their maximum values by more than 34% compared to the reference model OC. In addition, the results show that the LCC-OCR (light concrete column and ordinary concrete roof) and OCC-LCR (ordinary concrete for the column and light concrete for the roof) models' responses have fewer values than the other types.