레이저의 의학적 이용은 고출력 레이저의 외과적 이용과 더불어 많은 진전을 하게 되었다. 근래에는 인체에 손상을 주는 고출력 레이저 외에도 조직의 파괴없이 인체조직에 유용한 효과를 줄 수 있는 저출력 레이저에 대한 연구가 적극적으로 시도되고 있다. 본 연구는 치은염을 가진 13명의 대상에 대해 Split-mouth design으로 대조군 및 실험군을 설정하여 실험군의 치은에 저출력 레이저(Biotherapy dental Laser 3DL)를 격일로 4회 조사한 후 plaque index, pocket depth, sulcus bleeding index, supragingival과 subgingival plaque의 bacterial morphotype의 비율 및 광학현미경을 통한 조직학적 염증 침윤상을 측정 평가하여 다음과 같은 결과를 얻었다. 1) 레이저 조사후 SBI(p<0.01)는 감소하였으나 PI는 별다른 변화가 없었다. 2) 레이저 조사에 따라 spirochetes(p<0.01)를 포함하여 motiles(p<0.05, p<0.01)은 감소된 반면 nommotiles(p<0.05, p<0.01) 증가하였다. 3) 레이저 조사 치은에서는 염증세포 침윤이 Dental(p<0.05) 및 oral(p<0.01) 양측 모두 감소되었다.

In order to investigate the biostimulatory effect of low power density laser radiation in vitro, human gingival fibroblasts were cultured in MEM in which experiment groups respectively were made to 30 sec, 60 sec and 90 sec group. The experiments were performed by cell count, DNA and protein content measurements after experimental groups were irradiated with GaAlAs laser every day by forth day and then control group and experimental groups were compared. The results were as follows: 1. Cell counts of experimental groups were increased with exposure time, but showed no significance (P>0.05). 2. When the protein contents were compared, there was a very significant increase in 90 sec. experimental group (P<0.01). 3. When the DNA contents were compared, there was a significant difference only between control and 70 sec. group (P<0.05).

When the men die, uniform changes progress. Many investigators have studied about the time after death, but it's very difficult to measure the time elapsed since death, particularly in highly decomposed or probably skeletonized bodies. But the teeth are very stable to the changes of physical and chemical properties and their changes are very slow. At this point of view, the author studied this theme as one of the pioneers in our country. In this study, the author observed the degree of the dentinal expansion and the crack of enamel and cementum of the teeth which had been extracted from December, 1983 to September, 1987. The teeth were extracted from the male and female who was 18 to 85 year old. The results are followed; 1. The degree of dentinal expansion increased rapidly until 7 months with high degree and then decreased slowly. 2. The equation of regression for representing x as the degree of the dentinal expansion and y as the time elapsed since death, is y = 29.43-1.13x (p<0.05) 3. The crack of the enamel surface seemed to begin at 1 year from extraction and to increase apparently before or after 20 months. 4. The crack of the cementum began at 3 months from extraction and dendrite crack began at 16 months from extraction. After this, the crack increase continuously and the rate of cracking were more rapid as compared with that of enamel. 5. It seems to be useful to measure the time elapsed since death using the degree of dentinal expansion and the crack of enamel and cementum, particularly in the old bodies after death.

In order to study of muscle fiber proportion of masticatory muscle, 6 rabbits masticatory muscles (masseter, temporal, internal pterygoid, external pterygoid) were excised. Muscle specimens were fixed in 10% neutral buffered formalin fixer and sectioned $5{\mu}$ for PAS staining. With the light microscopic photograph the proportion of muscle fibers of each muscle were computed. The results were as follow; 1. Average classical red fiber proportion of rabbit masticatory muscles was 85.7% 2. Masseter muscle revealed 90.3% of classical red fiber in the rabbit masticatory muscles.

In order to evaluate the effect of signs and symptoms of temporomandibular disorders on the bite force of anterior teeth, the author estimated a feature of maintaining the maximum bite force on central incisors in Korean 34 adult females with signs and symptoms of temporomandibular disorders (TMD group) and in Korean 31 adult females within normal masticatory function far from any sign or symptom of TMD (control group), and analyzed the data statistically. The obtained results were as follows: 1. There was not a significant difference of the maximum bite force on central incisors between TMD group and control group (P>0.05). 2. The duration of maintaining the maximum bite force on central incisors in TMD group was shorter than it in control group (P<0.01).

In order to evaluate the effect of unilateral tooth clenching, the author observed a feature of producing the symptom complex related to pain and discomfort by the isometric unilateral canine biting under force of 5kg(FS) in Korean 31 adult females within normal masticatory function who were divided into the bilateral, the right and the left group according to their habitual sides of mastication, and analyzed the observed data statistically. The obtained results were as follows: 1. The duration of the isometric unilateral canine biting maintained before the occurrence of symptom complex related to pain and discomfort 66.72 seconds at right side and 39.50 seconds at left side in a group of subjects with bilateral habitual mastication. And the difference of the duration between of unilateral biting side was almost significant (P<0.05). 2. The most frequent region of occurrence of symptom complex related to pain and discomfort by the isometric unilateral canine biting was the contralateral superficial masseter muscle in a group of subjects with bilateral habitual mastication.

The life changes of TMJ patients were evaluated through the Social Readjustment Rating Scale (SRRS) questionnaire. 61 female TMJ patients and 80 dental new female outpatients were studied at the TMJ Clinics, Department of Oral Diagnosis, PNUH from February to September 1987. The obtained results were as follows; 1. The life change unit (LCU) totals and number of life events in the TMJ patients were significantly higher than those in the control subjects, especially during the 1-6 months before presentation for the hospital. 2. There was no significant difference in the number of the high-scored (over 150 LCU totals) between the TMJ patients and the control subjects. 3. There was a significant difference in LCU totals and life events between the TMJ patients and the control subjects by age, despite no difference in LCU totals and life events between the young and the advanced subgroups. 4. The LCU totals and the number of life events in the TMJ patients over 13-year-school age were significantly higher than those in the control subjects over 13-year-school age and the TMJ patients under 12-year-school age. 5. The married subgroup in the TMJ patients showed no significant difference in LCU totals and life events as compared with the unmarried one. 6. Categorizing life events into 6 items (marital life, health, occupation, family, finances and social), the TMJ patients had the higher frequencies in marital life and occupation than the control.

This study was designed to investigate the effects of TMJ incoordination to condylar movements, especially, the ISS. The sounds are one of the symptoms in TMJ incoordinated disorder, and it may cause the changes of mandibular movement trajectory. 19 students with only TMJ sounds and 16 students with no TMJ problems participated in this study. The subject performed Rt. lateral, Lt. lateral and protrusive movements, and repeated 3 times on each movement. Pantronic was used to record the measures of condylar movement paths. The obtained results were as follows : 1. The mean values of RISS and LISS in control group were 0.29mm, 0.36mm respectively, and those in experimental group were 0.49mm, 0.41mm repectively. The mean values of RISS was higher in experimental group than that of RISS in control group. 2. Correlation coefficients between PRI and RISS, LISS were slightly higher in experimental group than those in control group, therefore, PRI was more likely to be affected by ISS in experimental group. 3. In control group PRI was correlated to RISS, LORB, RPRO and LPRO, but in experimental group PRI was not correlated to those items. From the study, the author knew that the condylar movements was stable in control group.

The author studied on the effect of TMJ sounds to the patterns and ranges of mandibular border movements in horizontal plane with Pantograph (Denar Corp.). For study, 19 patients with TMJ sounds only and 16 students with no TM disorder were selected and classified as experimental group and control group, respectively. The subject performed right lateral movement, left lateral movement, and forward movement. Each movement were performed 3 times and the movement trajectory obtained with mechanical pantograph were observed for accordance of centric relation position, reproducibility and/or restriction of lateral movement paths, deviation of protrusive path in anterior table, restriction of protrusive condylar movement path in posterior horizontal table, presence of Fisher angle in posterior vertical table. And pantographic reproducibility Index (PRI) were obtained with pantronic by the same movement method as in the mechanical pantograph record. The obtained results were as follows : 1. In experimental group, PRI scores in those who show accordance of centric relation position were 14.4, and were 26.53 in those who did not show accordance of centric relation position. However, the PRI scores of the two subgroups show no statistically significant difference in control group. Therefore, in experimental group, the capability of accordance of centric relation position affected largely the PRI scores than in control group. 2. Deviation of protrusive path was opposite to the affected side in experimental group, and was left side in control group. 3. Restriction side of condylar movement in protrusion was ipsilateral to the deviation side in experimental group, but in control group, restriction side was not related to the deviation side. 4. PRI scores in experimental group were 23.2 (moderate dysfunction category), and in control group, were 17.8 (slight dysfunction category). The PRI scores in control group, however, implies that the evaluation of temporomandibular disorders by the PRI scores only may be unreasonable.

저자는 측두하악장애를 가진 환자 15명을 대상으로 교합안정장치 장착 전후의 Helkimo 장애지수 및 교근의 휴지기 지속시간을 측정한 결과 마음과 같은 결론을 얻었다. 측두하악장애를 가진 환자 15명의 실험전 평균 교근휴지기 지속시간은 좌측에서는 50.7msec 우측에서는 50.5msec였다. 교합안정장치를 이용한 4주간의 치료후 평균 교근 휴지기지속시간은 좌측에서는 25.4msec 우측에서는 26.5msec였다. 치료전 Helkimo 기능장애지수와 교근의 휴지기 지속시간과는 상관관계가 높았다.(r : 0.675, p<0.01). Helkimo 기능장애지수는 교합안정장치장착 4주후 현저히 감소하였다. (p<0.01). 교근의 휴지기 지속시간도 교합안정장치장착 4주후 현저히 감소하였다. (p<0.01).