한국의학물리학회지:의학물리 (Progress in Medical Physics)

  • 제35권2호
  • /
  • Pages.36-44
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  • 2024
  • /
  • 2508-4445(pISSN)
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  • 2508-4453(eISSN)
한국의학물리학회 (Korean Society of Medical Physics)
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Dosimetric Evaluations of HyperArc and RapidArc in Stereotactic Radiosurgery for a Single Brain Metastasis

  • So-Yeon Park (Department of Radiation Oncology, Veterans Health Service Medical Center) ;
  • Noorie Choi (Department of Radiation Oncology, Veterans Health Service Medical Center) ;
  • Na Young Jang (Department of Radiation Oncology, Veterans Health Service Medical Center)
  • 투고 : 2024.02.21
  • 심사 : 2024.03.25
  • 발행 : 2024.06.30
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초록

Purpose: This study assessed and compared the dosimetric performance of HyperArc and RapidArc in stereotactic radiosurgery (SRS) for a single brain metastasis. Methods: Twenty patients with intracranial brain metastases, each presenting a distinct target volume, were retrospectively selected. Subsequently, volumetric modulated arc therapy (VMAT) plans were designed using RapidArc (VMATRA) and HyperArc (VMATHA) for each patient. For planning comparisons, dose-volumetric histogram (DVH) parameters for planning target volumes (PTVs) and normal brain regions were computed across all VMAT plans. Subsequently, their total monitor units (MUs), total beam-on times, and modulation complexity scores for the VMAT (MCSv) were compared. A statistical test was used to evaluate the dosimetric disparities in the DVH parameters, total MUs, total beam-on times, and MCSv between the VMATHA and VMATRA plans. Results: For the PTVs, VMATHA presented a higher homogeneity index (HI) than VMATRA. Moreover, VMATHA presented significantly smaller gradient index (GI) values (P<0.001) than VMATRA. Thus, VMATHA demonstrated better performance in the DVH parameters for the PTV than VMATRA. For normal brain tissues, VMATHA presented lower volume receiving 50% of the prescription dose and V2Gy to the normal brain tissues than VMATRA (P<0.0001). While the total MUs required for VMATHA was significantly higher than those for VMATRA, the total beam-on time for VMATHA was superior to that for VMATRA. Conclusions: Thus, VMATHA exhibited superior performance in achieving rapid dose fall-offs (as indicated by the GI) and a higher HI at the PTV compared to VMATRA in brain SRS. This advancement positions HyperArc as a significant development in the field of radiation therapy, offering optimized treatment outcomes for brain SRS.

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과제정보

This study was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2023-00253604).

참고문헌

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