Progress in Medical Physics (한국의학물리학회지:의학물리)

Korean Society of Medical Physics (한국의학물리학회)
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Dosimetric Evaluations of HyperArc and RapidArc in Stereotactic Radiosurgery for a Single Brain Metastasis

  • So-Yeon Park (Department of Radiation Oncology, Veterans Health Service Medical Center) ;
  • Noorie Choi (Department of Radiation Oncology, Veterans Health Service Medical Center) ;
  • Na Young Jang (Department of Radiation Oncology, Veterans Health Service Medical Center)
  • Received : 2024.02.21
  • Accepted : 2024.03.25
  • Published : 2024.06.30
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Abstract

Purpose: This study assessed and compared the dosimetric performance of HyperArc and RapidArc in stereotactic radiosurgery (SRS) for a single brain metastasis. Methods: Twenty patients with intracranial brain metastases, each presenting a distinct target volume, were retrospectively selected. Subsequently, volumetric modulated arc therapy (VMAT) plans were designed using RapidArc (VMATRA) and HyperArc (VMATHA) for each patient. For planning comparisons, dose-volumetric histogram (DVH) parameters for planning target volumes (PTVs) and normal brain regions were computed across all VMAT plans. Subsequently, their total monitor units (MUs), total beam-on times, and modulation complexity scores for the VMAT (MCSv) were compared. A statistical test was used to evaluate the dosimetric disparities in the DVH parameters, total MUs, total beam-on times, and MCSv between the VMATHA and VMATRA plans. Results: For the PTVs, VMATHA presented a higher homogeneity index (HI) than VMATRA. Moreover, VMATHA presented significantly smaller gradient index (GI) values (P<0.001) than VMATRA. Thus, VMATHA demonstrated better performance in the DVH parameters for the PTV than VMATRA. For normal brain tissues, VMATHA presented lower volume receiving 50% of the prescription dose and V2Gy to the normal brain tissues than VMATRA (P<0.0001). While the total MUs required for VMATHA was significantly higher than those for VMATRA, the total beam-on time for VMATHA was superior to that for VMATRA. Conclusions: Thus, VMATHA exhibited superior performance in achieving rapid dose fall-offs (as indicated by the GI) and a higher HI at the PTV compared to VMATRA in brain SRS. This advancement positions HyperArc as a significant development in the field of radiation therapy, offering optimized treatment outcomes for brain SRS.

Keywords

Acknowledgement

This study was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2023-00253604).

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