Journal of the Korea Institute of Military Science and Technology (한국군사과학기술학회지)

The Korea Institute of Military Science and Technology (한국군사과학기술학회)
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A Study on the Efficacy of Four Chemical Decontaminants against High-concentration Surrogates of Bacteria, Toxin, and Virus Biological Agents

고농도 세균, 독소, 바이러스 모의 생물 작용제에 대한 제독제 4종 효과 연구

  • Hanwool Park (Chem-Bio Center, Agency for Defense Development) ;
  • Yeonghwan Seo (Chem-Bio Center, Agency for Defense Development) ;
  • Hongsuk Lee (Chem-Bio Center, Agency for Defense Development) ;
  • Seongjoo Kim (Chem-Bio Center, Agency for Defense Development)
  • 박한울 (국방과학연구소 Chem-Bio센터) ;
  • 서영환 (국방과학연구소 Chem-Bio센터) ;
  • 이홍석 (국방과학연구소 Chem-Bio센터) ;
  • 김성주 (국방과학연구소 Chem-Bio센터)
  • Received : 2024.07.18
  • Accepted : 2024.08.13
  • Published : 2024.10.05
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Abstract

If a nation or a terrorist organization produced biological agents, they are likely stored in a form of liquid concentrate. In the present study, four chemical reagents, hydrogen peroxide, sodium dichloroisocyanurate (NaDCC), Perasafe, and DF200, were investigated on their potentials as safe, efficient and eco-friendly decontaminants for biological agents. Escherichia coli, α-amylase, and bacteriophage T4 were used as surrogate strains for biological agents. Hydrogen peroxide and DF200 showed drawbacks of a rapid heat evolution upon neutralization and thick foam building up, respectively. Perasafe was effective against E. coli and T4, but it did not inactivate α-amylase while the others were able to inactivate all three types of the surrogates. NaDCC was the most suitable decontaminant for its effectiveness against all three types of surrogates at low concentrations and being able to be neutralized without aforementioned problems.

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