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Diagnosis of Human Immunodeficiency Virus Infection

사람면역결핍바이러스 감염의 진단

  • Shi Nae Yu ( Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine)
  • 유시내 (순천향대학교 의과대학 순천향대학교 천안병원 감염내과)
  • Received : 2024.01.08
  • Accepted : 2024.01.25
  • Published : 2024.02.01

Abstract

Early diagnosis and early treatment of human immunodeficiency virus (HIV) infection are essential for clinical and public health benefits. Diagnostic algorithms for early diagnosis are being emphasized, and rapid tests at the point of care have been expanded to improve voluntary testing rates. Despite advances in laboratory diagnostic tests, early HIV infection can still be missed due to window periods, and it is crucial to recognize the limitations of testing methods and the potential for false negative and false positive results.

Keywords

Acknowledgement

This work was supported by the Soonchunhyang University Research Fund.

References

  1. Joint United Nations Programme on HIV/AIDS (UNAIDS). Global HIV & AIDS statistics - fact sheet [Internet]. Geneva (CH): UNAIDS, c2023 [cited 2023 Dec 30]. Available from: https://www.unaids.org/en/resources/fact-sheet.
  2. Korea Disease Control and Prevention Agency (KDCA). Annual report on the notified HIV/AIDS in Korea 2022. Cheongju: KDCA, 2023.
  3. Lee E, Kim J, Lee JY, Bang JH. Estimation of the number of HIV infections and time to diagnosis in the Korea. J Korean Med Sci 2020;35:e41.
  4. Branson BM, Owen SM, Wesolowski LG, et al. Laboratory testing for the diagnosis of HIV infection: updated recommendations [Internet]. Atlanta (US): Centers for Disease Control and Prevention, c2014 [cited 2023 Dec 30]. Available from: https://stacks.cdc.gov/view/cdc/23447.
  5. Hurt CB, Nelson JAE, Hightow-Weidman LB, Miller WC. Selecting an HIV test: a narrative review for clinicians and researchers. Sex Transm Dis 2017;44:739-746. https://doi.org/10.1097/OLQ.0000000000000719
  6. Parekh BS, Ou CY, Fonjungo PN, et al. Diagnosis of human immunodeficiency virus infection. Clin Microbiol Rev 2018;32:e00064-18.
  7. Francesco RS, Robin D, Frank M. Diagnosis of human immunodeficiency virus infection. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 9th ed. Philadelphia: Elsevier, 2019:1619-1641.
  8. Korean Society of Infectious Diseases. Infectious diseases. Paju: Koonja, 2014.
  9. Franco-Paredes C, Tellez I, del Rio C. Rapid HIV testing: a review of the literature and implications for the clinician. Curr HIV/AIDS Rep 2006;3:169-175. https://doi.org/10.1007/s11904-006-0012-3
  10. Yang HJ, Kim J, Bang JH, et al. Three-year outcome of rapid HIV testing at public health centers in Seoul, Republic of Korea: a short report. AIDS Care 2021;33:525-529. https://doi.org/10.1080/09540121.2020.1749550
  11. Wang JS, Sim HJ, Park SJ, Park GR, Kang C, Chung YS. Effect of a confirmatory testing algorithm on early acute HIV diagnosis in Korea. Medicine (Baltimore) 2021;100:e25632.
  12. Korea Disease Control and Prevention Agency (KDCA). HIV/AIDS management guideline [Internet]. Cheongju (KR): KDCA, c2023 [cited 2023 Dec 30]. Available from: https://www.kdca.go.kr/board/board.es?mid=a20507020000&bid=0019.