The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A 32-Year-Old Female with Incidentally Detected Multifocal Cystic Pulmonary Lesions on Chest Computed Tomography

흉부 CT에서 우연히 발견된 다발성 낭성 폐병변을 가진 32세 여성

  • Hee-Young Yoon (Division of Allergy and Respiratory Diseases, Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine)
  • 윤희영 (순천향대학교 의과대학 순천향대학교 서울병원 호흡기알레르기내과)
  • Received : 2023.11.21
  • Accepted : 2024.01.23
  • Published : 2024.02.01
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Abstract

Lymphangioleiomyomatosis (LAM) is a rare condition that exclusively affects women and is characterized by lung parenchymal destruction and the formation of cysts due to infiltration by LAM cells. It can also impact the lymphatic system, leading to the development of fluid-filled cystic structures and abdominal involvement, including renal angiomyolipomas (AML) or lymphangioleiomyoma. LAM can occur sporadically or be associated with tuberous sclerosis complex. Common symptoms include respiratory issues such as dyspnea, pneumothorax, chylothorax, along with other manifestations like renal AML and lymphatic involvement. The diagnosis of LAM relies on a combination of clinical, radiological, and laboratory findings, and treatment options vary depending on symptoms and patient status, with mTOR inhibitors being considered as a treatment option. This case outlines the diagnostic journey and clinical course of a 32-year-old female patient with LAM.

Keywords

Acknowledgement

This paper was supported by Soonchunhyang University Research Fund.

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