Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics

  • Yi‑Tong Zhou (College of Life Science and Technology, Huazhong University of Science and Technology) ;
  • Pei‑Jie Zhang (College of Life Science and Technology, Huazhong University of Science and Technology) ;
  • Shu‑Ping Wang (State Grid Anhui Electric Power Co., Ltd) ;
  • Chang‑Hao Li (State Grid Anhui Electric Power Co., Ltd) ;
  • Jia‑Qing Zhang (State Grid Anhui Electric Power Co., Ltd) ;
  • Wei‑Xin Zhang (State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology) ;
  • Yuan‑Di Zhao (College of Life Science and Technology, Huazhong University of Science and Technology) ;
  • Yuan‑Cheng Cao (State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology) ;
  • Jin‑Xuan Fan (College of Life Science and Technology, Huazhong University of Science and Technology)
  • Received : 2023.11.20
  • Accepted : 2024.03.22
  • Published : 2024.07.15
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Abstract

The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat dissipation of IDC is indispensable due to it generates a large amount of heat during its calculation process, which may potentially harm its normal operation. Electronic fluorinated fluids have been widely used in cooling systems of IDC with stable physical and chemical properties. However, the biological toxicity of electronic fluorinated fluids has not been fully evaluated and there is a lack of unified safety standards, which may pose potential risks to the environment and human health. Here, hexafluoropropylene terpolymer (HFPT) as an example has been systematically studied, fully considering the application scenarios of data centers. Also, the emergency effects of fluorinated coolants in mammalian models from the perspectives of inhalation, skin contact, accidental entry into eyes, accidental ingestion, and chronic toxicity, are evaluated. Multiple in vivo experiments have proven that HFPT not only has stable physical and chemical properties, that can maintain the safe operation of IDC, but also has low physiological toxicity to mammals and can provide health benefits to data center staff and the assurance of surrounding environment. This study proves the good biological safety of electronic fluorinated fluids and provides a reference for environmental assessment and risk management of liquid cooling technology in IDC.

Keywords

Acknowledgement

All animal experiments were approved by the Animal Experiment Ethics Committee of Huazhong University of Science and Technology. We also thank the Analytical and Testing Centre (HUST), the Research Core Facilities for Life Science (HUST) and the Centre for Nanoscale Characterization & Devices (CNCD) at WNLO of HUST for the help of measurement.

References

  1. Geng H (2014) Data centers-strategic planning, design, construction, and operations. Data center handbook. Wiley, Hoboken, pp 1-14 
  2. Kant K (2009) Data center evolution. A tutorial on state of the art, issues, and challenges. Comput Netw 53:2939-2965. https://doi.org/10.1016/j.comnet.2009.10.004 
  3. Muhammad S, Pan Y, Magazzino C, Luo Y, Waqas M (2022) The fourth industrial revolution and environmental efficiency: the role of fintech industry. J Clean Prod 381:135-196. https://doi.org/10.1016/j.jclepro.2022.135196 
  4. Rong H, Zhang H, Xiao S, Li C, Hu C (2016) Optimizing energy consumption for data centers. Renew Sust Energ Rev 58:674-691. https://doi.org/10.1016/j.rser.2015.12.283 
  5. Cui DE, Zhou C, Luo Y, Lei Q, Tian Z, Zhang S, Fan J, Zhang L (2023) Multi-scale modeling and fast inference for thermal environment analysis of air-cooled data center. J Build Eng 78:107722. https://doi.org/10.1016/j.jobe.2023.107722 
  6. Shao X, Zhang Z, Song P, Feng Y, Wang X (2022) A review of energy effciency evaluation metrics for data centers. Energ Buildings 271:112308. https://doi.org/10.1016/j.enbuild.2022.112308 
  7. Ma X, Shi W, Yang H (2023) Improving the performance of indirect evaporative cooler for energy recovery from the perspective of nozzle configuration: a CFD model analysis. J Build Eng 76:107195. https://doi.org/10.1016/j.jobe.2023.107195 
  8. Zhang Y, Shan K, Li X, Li H, Wang S (2023) Research and Technologies for next-generation high-temperature data centers - State-of-the-arts and future perspectives. Renew Sust Energ Rev 171:112991. https://doi.org/10.1016/j.rser.2022.112991 
  9. Han X, Tian W, VanGilder J, Zuo W, Faulkner C (2021) An open source fast fluid dynamics model for data center thermal management. Energ Build 230:110599. https://doi.org/10.1016/j.enbuild.2020.110599 
  10. Zhang Q, Meng Z, Hong X, Zhan Y, Liu J, Dong J, Bai T, Niu J, Deen MJ (2021) A survey on data center cooling systems: technology, power consumption modeling and control strategy optimization. J Syst Archit 119:102253. https://doi.org/10.1016/j.sysarc.2021.102253 
  11. Haghshenas K, Setz B, Blosch Y, Aiello M (2023) Enough hot air: the role of immersion cooling. Energy Informatics 6:14. https://doi.org/10.1186/s42162-023-00269-0 
  12. Deymi-Dashtebayaz M, Valipour Namanlo S, Arabkoohsar A (2019) Simultaneous use of air-side and water-side economizers with the air source heat pump in a data center for cooling and heating production. Appl Therm Eng 161:114-133. https://doi.org/10.1016/j.applthermaleng.2019.114133 
  13. Nada SA, Said MA (2017) Comprehensive study on the effects of plenum depths on air flow and thermal managements in data centers. Int J Therm Sci 122:302-312. https://doi.org/10.1016/j.ijthermalsci.2017.09.001 
  14. Tradat MI, Manaserh YMA, Sammakia BG, Hoang CH, Alissa HA (2021) An experimental and numerical investigation of novel solution for energy management enhancement in data centers using underfloor plenum porous obstructions. Appl Energ 289:116663. https://doi.org/10.1016/j.apenergy.2021.116663 
  15. Deymi-Dashtebayaz M, Farahnak M, Abadi RNB (2019) Energy saving and environmental impact of optimizing the number of condenser fans in centrifugal chillers under partial load operation. Int J Refrig 103:163-179. https://doi.org/10.1016/j.ijrefrig.2019.03.020 
  16. Deymi-Dashtebayaz M, Farahnak M, Morafa M, Ghalami A, Mohammadi N (2018) Experimental evaluation of refrigerant mass charge and ambient air temperature effects on performance of air-conditioning systems. Heat Mass Transfer 54:803-812. https://doi.org/10.1007/s00231-017-2173-6 
  17. Zhang K, Zhang Y, Liu J, Niu X (2018) Recent advancements on thermal management and evaluation for data centers. Appl Therm Eng 142:215-231. https://doi.org/10.1016/j.applthermaleng.2018.07.004 
  18. Mi R, Bai X, Xu X, Ren F (2023) Energy performance evaluation in a data center with water-side free cooling. Energ Build 295:113278. https://doi.org/10.1016/j.enbuild.2023.113278 
  19. Jin C, Bai X, Yang C (2019) Effects of airflow on the thermal environment and energy efficiency in raised-floor data centers: a review. Sci Total Environ 695:133801. https://doi.org/10.1016/j.scitotenv.2019.133801 
  20. Li D, Zhang Y, Song J, Liu H, Jiang J (2022) Energy saving with zero hot spots: a novel power control approach for sustainable and stable data centers. Sustainability 14:9005. https://doi.org/10.3390/su14159005 
  21. Li Z, Kandlikar SG (2015) Current status and future trends in data-center cooling technologies. Heat Transf Eng 36:523-538. https://doi.org/10.1080/01457632.2014.939032 
  22. Luo Q, Wang C, Wu C (2023) Study on heat transfer performance of immersion system based on SiC/white mineral oil composite nanofluids. Int J Therm Sci 187:108-203. https://doi.org/10.1016/j.ijthermalsci.2023.108203 
  23. Kuncoro IW, Pambudi NA, Biddinika MK, Widiastuti I, Hijriawan M, Wibowo KM (2019) Immersion cooling as the next technology for data center cooling: a review. J Phys: Conf Ser 1402:044-057. https://doi.org/10.1088/1742-6596/1402/4/044057 
  24. Tong Z, Han Z, Fang C, Wen X (2023) Two-phase thermosyphon loop with different working fluids used in data centers. Int J Heat Mass Transf 214:124393. https://doi.org/10.1016/j.ijheatmasstransfer.2023.124393 
  25. Ji X, Yang X, Zhang Y, Zhang Y, Wei J (2022) Experimental study of ultralow fow resistance fractal microchannel heat sinks for electronics cooling. Int J Therm Sci 179:107723. https://doi.org/10.1016/j.ijthermalsci.2022.107723 
  26. Zhang H, Shao S, Xu H, Zou H, Tian C (2014) Free cooling of data centers: a review. Renew Sust Energ Rev 35:171-182. https://doi.org/10.1016/j.rser.2014.04.017 
  27. Poller WC, Downey J, Mooslechner AA, Khan N, Li L, Chan CT, McAlpine CS, Xu C, Kahles F, He S, Janssen H, Mindur JE, Singh S, Kiss MG, Alonso-Herranz L, Iwamoto Y, Kohler RH, Wong LP, Chetal K, Russo SJ, Sadreyev RI, Weissleder R, Nahrendorf M, Frenette PS, Divangahi M, Swirski FK (2022) Brain motor and fear circuits regulate leukocytes during acute stress. Nature 607:578-584. https://doi.org/10.1038/s41586-022-04890-z