• Proceedings of the Korean Society of Crop Science Conference
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• 2023.04a
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• pp.151-151
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• 2023

• Journal of the Korea Institute of Military Science and Technology
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• v.18 no.3
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• pp.335-342
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• 2015

Laboratory facilities for biology are designed as biosafety level 1, biosafety level 2, biosafety level 3, and biosafety level 4. Biosafety level designations are based on a composite of the design features, construction, containment facilities, equipment, practice and operation procedures required for working with agents from the various risk groups. Generally, biosafety level 3 means the facility that is appropriate for the experiments using pathogens which can cause serious diseases by aerosol transmission. The biosafety level assigned for the specific work to be done is driven by professional judgement based on a risk assessment, rather than by automatic assignment according to the particular risk group designation of the pathogenic agents to be used. In this paper, we introduced the biosafety level 3 facility operated in ADD(Agency for defense development). It contains the overview of facility, microbiological experiment, animal experiment, decontamination and waste disposal. Biosafety level 3 laboratory in ADD has served the vital role in the research of biological agents and antidote development.

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2005.11a
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• pp.83.1-84
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• 2005

• Korean Journal of Veterinary Service
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• v.29 no.4
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• pp.503-506
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• 2006

Cyclopia is a congenital ocular abnormality in which two orbits are fused together due to an arrest in the normal process of embryonic tissue development. Reported here is a case of cyclopia in a calf observed from the uterus of cow slaughtered in an abattoir in Korea on March 24, 2004. The calf possessed a spherical-shaped head and only one centrally placed eye. The one eyeball showed complete eyelashes on the defective eyelids. The nasal region and the anterior nares were absent along with a dorsally curved mandible extended beyond the defective maxillae.

• Safety and Health at Work
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• v.8 no.1
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• pp.49-58
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• 2017

Background: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. Methods: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory biosafety, availability and proper use of personal protective equipment (PPE), any priority pathogens researched, attitude on and use of standard laboratory practices, and biosafety awareness was obtained using a numeric scoring system. Data were analyzed with descriptive statistics, and univariate and multivariate logistic regression. Results: A total of 74 participants from 19 facilities completed the questionnaire. General knowledge scores ranged from 3 to 28 (out of 28 possible points), with 94.6% of respondents receiving low scores (scores < mean + 1 standard deviation). Very few (17.6%) reported availability or use PPE. Many participants (63.5%) reported no access to biosafety level (BSL)-1-3 facilities. None reported availability of a BSL-4 facility. Knowledge scores pertaining to biosafety management practices ranged from 0 to 14 (out of 14 possible points) with 47.3% of respondents receiving good scores (scores > mean + 1 standard deviation). Only 16.2% of respondents (from four facilities) reported having biosafety officers. Rabies virus was the most researched pathogen (31.1% of respondents). The majority (71.6%) were unaware of laws guiding biosafety. Researchers [odds ratio (OR) = 18.0; 95% confidence interval (CI): 1.63, 198.5; p = 0.023], especially in BSL-2 (OR = 258.5; 95% CI: 12.71, 5256; p < 0.001) facility of research institute (OR = 25.0; 95% CI: 5.18, 120.6; p < 0.001), are more likely to have adequate access to and properly utilize biosafety devices and PPE. Conclusions: Current knowledge of laboratory biosafety is limited except among a few researchers.

• Journal of Ginseng Research
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• v.45 no.3
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• pp.450-455
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• 2021

Korean Red Ginseng (KRG) is an herbal oriental medicine known to alleviate cardiovascular dysfunction. To analysis the expression of diabetic cardiac complication-associated genes in db/db mice, we studied the cardiac gene expression following KRG treatment. In result, a total of 585 genes were found to be changed in db/db mice. Among the changed expression, 245 genes were found to 2-fold upregulated, and 340 genes were 2-fold downregulated. In addition, the changed gene expressions were ameliorated by KRG. In conclusion, KRG may be possible to normalize cardiac gene expressions in db/db mice.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2004.11a
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• pp.146-146
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• 2004

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.887-892
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• 2009

Biosafety research facilities require to verified about the facility and experimental environment, especially for level-3 and level-4 of biosafety research facilities verification is very important. In this paper, introduce verified procedures and present the methods and the results through a verified case of the biosafety level-3 research facilities.

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2004.10a
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• pp.34-34
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• 2004

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2004.10a
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• pp.35-35
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• 2004