Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Optimization of Mixture Composition to Improve Emulsifying Power and Solubilization of Sucrose Stearate

수크로스 스테아레이트의 유화력 및 가용화력 향상을 위한 혼합물 조성 최적화

  • Jong Hwan Bae (Department of Applied Chemistry, Dongduk Women's University) ;
  • Maria Song (Department of Health and cosmetics, Dongduk Women's University) ;
  • Byung Suk Jin (Department of Applied Chemistry, Dongduk Women's University)
  • 배종환 (동덕여자대학교 응용화학과) ;
  • 송마리아 (동덕여자대학교 보건향장학과) ;
  • 진병석 (동덕여자대학교 응용화학과)
  • Received : 2024.02.19
  • Accepted : 2024.04.24
  • Published : 2024.04.30
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Abstract

In this study, we enhanced the emulsifying power and solubilization of sucrose stearate (SS) by creating mixtures with sodium deoxycholate (SDOC) and PEG-40 hydrogenated castor oil (HCO). We employed the design of mixture experiments (DOME) methodology to identify the optimal composition of the mixture, and the impact of varying the mixture composition on its characteristics was examined through regression analysis of the experimental data. It was revealed that the emulsifying power for coconut oil was most improved when only SDOC was added to SS, and solubilization was most improved when only HCO was added, while the emulsifying power for cetyl ethylhexanoate (CEH) was most significantly improved when SDOC and HCO were added together. As a result of simultaneous optimization of three characteristics, emulsifying power for each of coconut oil and CEH, and solubilization, the optimal surfactant mixture composition was determined as SS 0.7939, SDOC 0.0586, and HCO 0.1475.

본 연구에서는 수크로스 스테아레이트(SS)의 유화력과 가용화력을 좀 더 향상시키기 위해, sodium deoxycholate (SDOC)와 PEG-40 hydrogenated castor oil (HCO)와의 혼합 조성물을 구성하였다. 혼합물의 최적 조성을 구하기 위해 혼합물 실험 계획법을 도입하여 실험을 진행하고, 실험에서 얻은 데이터를 회귀 분석하여 혼합물 조성의 변화가 혼합물의 특성에 미치는 영향을 살펴보았다. SS에 SDOC만을 첨가했을 때 코코넛 오일에 대한 유화력이 가장 향상되고, HCO만을 첨가했을 때는 가용화력이 가장 향상된 반면, 에스테르 오일인 cetyl ethylhexanoate (CEH)에 대한 유화력은 SDOC와 HCO를 함께 첨가했을 때 가장 크게 향상됨을 알 수 있었다. 코코넛 오일 및 CEH 각각에 대한 유화력과 가용화력, 3개의 특성치에 대한 동시 최적화를 실시한 결과, 최적의 계면활성제 혼합 조성은 SS 0.7939, SDOC 0.0586, HCO 0.1475로 구해졌다.

Keywords

Acknowledgement

본 연구는 산업통상자원부의 바이오산업기술개발사업(과제번호 20018375)의 지원에 의하여 수행된 결과의 일부이며 이에 감사의 뜻을 표합니다.

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