Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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A Study on the Physiological Activity of Cosmetics in Bupleurum falcatum L. Extract

시호 추출물의 화장품 생리활성에 관한 연구

  • Il-Young Cho (Department of Cosmetic science, Hoseo University) ;
  • Yong-Sub Yi (Department of Cosmetic biotechnology, Hoseo University) ;
  • Yong-Hwa Lee (Department of Cosmetic biotechnology, Hoseo University)
  • 조일영 (호서대학교 화장품과학과) ;
  • 이용섭 (호서대학교 화장품생명공학부) ;
  • 이용화 (호서대학교 화장품생명공학부)
  • Received : 2023.03.21
  • Accepted : 2024.02.29
  • Published : 2024.02.28
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Abstract

Bupleurum falcatum L. is one of the medicinal crops and has excellent pharmacological activities such as reducing fever, sedation, inhibition of hepatopathy, anti-inflammatory, and anticancer. Currently, it is used for food or medicine, but the use as a cosmetic is insufficient, so the suitability and use value as a cosmetic material were reviewed. Using the Bupleurum falcatum L. extract, polyphenol, flavonoid, antioxidant, and anti-inflammatory tests were conducted. The total polyphenol content was 14.71±0.16 mg·TAE/g, and the total flavonoid content was 1.42±0.05 mg·QE/g. The antioxidant activity showed excellent activity in a concentration-dependent activative, and the NO expression inhibition ability was 61.21% at 1,000 ㎍/mL, confirming that the anti-inflammatory activity was excellent. Through this study, the antioxidant and anti-inflammatory effects of Bupleurum falcatum L. extract are excellent, so it is considered to be of sufficient value as a natural material for cosmetics.

시호는 약용작물의 하나로 해열, 진정, 간 장애 억제, 항염, 항암 등 우수한 약리 활성을 지니고 있다. 현재 식품 또는 약용으로 사용되고 있지만 화장품으로서의 사용은 미비하여 화장품 소재로서의 적합성 및 이용 가치를 검토하였다. 시호 추출물을 이용하여 폴리페놀, 플라보노이드, 항산화, 항염 실험을 진행하였다. 폴리페놀 함량은 14.71±0.16 mg·TAE/g, 플라보노이드 함량은 1.42±0.05 mg·QE/g를 나타내었다. 항산화 활성은 농도 의존적으로 우수한 활성을 보였으며, NO 발현 억제능은 1,000 ㎍/mL에서 61.21%의 저해율을 나타내어 항염 활성이 뛰어남을 확인하였다. 본 연구를 통해 시호 추출물의 항산화, 항염 효능이 뛰어나기에 화장품의 천연 소재로서 충분한 가치가 있다고 본다.

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