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Trends in Research on Patients With COVID-19 in Korean Medical Journals

  • Heejeong Choi (Department of Medicine, Chosun University College of Medicine) ;
  • Seunggwan Song (Department of Medicine, Chosun University College of Medicine) ;
  • Heesang Ahn (Department of Medicine, Chosun University College of Medicine) ;
  • Hyobean Yang (Department of Medicine, Chosun University College of Medicine) ;
  • Hyeonseong Lim (Department of Medicine, Chosun University College of Medicine) ;
  • Yohan Park (Department of Medicine, Chosun University College of Medicine) ;
  • Juhyun Kim (Department of Medicine, Chosun University College of Medicine) ;
  • Hongju Yong (Department of Medicine, Chosun University College of Medicine) ;
  • Minseok Yoon (Department of Medicine, Chosun University College of Medicine) ;
  • Mi Ah Han (Department of Preventive Medicine, Chosun University College of Medicine)
  • Received : 2023.06.02
  • Accepted : 2023.12.27
  • Published : 2024.01.31

Abstract

Objectives: This study was conducted to systematically summarize trends in research concerning patients with coronavirus disease 2019 (COVID-19) as reported in Korean medical journals. Methods: We performed a literature search of KoreaMed from January 2020 to September 2022. We included only primary studies of patients with COVID-19. Two reviewers screened titles and abstracts, then performed full-text screening, both independently and in duplicate. We first identified the 5 journals with the greatest numbers of eligible publications, then extracted data pertaining to the general characteristics, study population attributes, and research features of papers published in these journals. Results: Our analysis encompassed 142 primary studies. Of these, approximately 41.0% reported a funding source, while 3.5% disclosed a conflict of interest. In 2020, 42.9% of studies included fewer than 10 participants; however, by 2022, the proportion of studies with over 200 participants had increased to 40.6%. The most common design was the cohort study (48.6%), followed by case reports/series (35.2%). Only 3 randomized controlled trials were identified. Studies most frequently focused on prognosis (58.5%), followed by therapy/intervention (20.4%). Regarding the type of intervention/exposure, therapeutic clinical interventions comprised 26.1%, while studies of morbidity accounted for 13.4%. As for the outcomes measured, 50.7% of studies assessed symptoms/clinical status/improvement, and 14.1% evaluated mortality. Conclusions: Employing a systematic approach, we examined the characteristics of research involving patients with COVID-19 that was published in Korean medical journals from 2020 onward. Subsequent research should assess not only publication trends over a longer timeframe but also the quality of evidence provided.

Keywords

References

  1. Korea Disease Control and Prevention Agency. Coronavirus (COVID-19), Republic of Korea [cited 2022 Dec 15]. Available from: https://ncov.kdca.go.kr/ (Korean).
  2. World Health Organization. WHO COVID-19 dashboard [cited 2022 Dec 15]. Available from: https://covid19.who.int/
  3. Chu DT, Vu Ngoc SM, Vu Thi H, Nguyen Thi YV, Ho TT, Hoang VT, et al. COVID-19 in Southeast Asia: current status and perspectives. Bioengineered 2022;13(2):3797-3809. https://doi.org/10.1080/21655979.2022.2031417
  4. Tu H, Wang X, Tang S. Exploring COVID-19 transmission patterns and key factors during epidemics caused by three major strains in Asia. J Theor Biol 2023;557:111336. https://doi.org/10.1016/j.jtbi.2022.111336
  5. Nham E, Song JY, Noh JY, Cheong HJ, Kim WJ. COVID-19 vaccination in Korea: past, present, and the way forward. J Korean Med Sci 2022;37(47):e351. https://doi.org/10.3346/jkms.2022.37.e351
  6. Parohan M, Yaghoubi S, Seraji A, Javanbakht MH, Sarraf P, Djalali M. Risk factors for mortality in patients with coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies. Aging Male 2020;23(5):1416-1424. https://doi.org/10.1080/13685538.2020.1774748
  7. Siemieniuk RA, Bartoszko JJ, Zeraatkar D, Kum E, Qasim A, Martinez JP, et al. Drug treatments for COVID-19: living systematic review and network meta-analysis. BMJ 2020;370:m2980. https://doi.org/10.1136/bmj.m2980
  8. Update to living WHO guideline on drugs for COVID-19. BMJ 2022;378:o2224. https://doi.org/10.1136/bmj.o2224
  9. Abali H, Kutbay Ozcelik H, Akkutuk Ongel E, Beyhan N, Tokgoz Akyil F, Tural Onur S, et al. Prognostic predictors for mortality of patients with COVID-19 in an intensive care unit. J Infect Dev Ctries 2022;16(10):1555-1563. https://doi.org/10.3855/jidc.16973
  10. Raez LE, Tarockoff M, Carracedo Uribe CR, Niu J, Sareli C, Sundararaman N, et al. Mortality and prognostic factors in hospitalized COVID-19 patients with cancer: an analysis from a large healthcare system in the United States. Ann Transl Med 2022;10(20):1090. https://doi.org/10.21037/atm-22-1667
  11. Walle-Hansen MM, Ranhoff AH, Mellingsaeter M, Wang-Hansen MS, Myrstad M. Health-related quality of life, functional decline, and long-term mortality in older patients following hospitalisation due to COVID-19. BMC Geriatr 2021;21(1):199. https://doi.org/10.1186/s12877-021-02140-x
  12. Lee CH. COVID-19 literature published in emergency medicine journals in 2020. West J Emerg Med 2022;23(3):432-438. https://doi.org/10.5811/westjem.2022.1.55029
  13. Khalifa AA, Ahmed AM. How fast is the peer-review process for orthopaedic publications related to the Covid-19 pandemic? J Clin Orthop Trauma 2021;12(1):9-15. https://doi.org/10.1016/j.jcot.2020.09.007
  14. Li Y, Cao L, Zhang Z, Hou L, Qin Y, Hui X, et al. Reporting and methodological quality of COVID-19 systematic reviews needs to be improved: an evidence mapping. J Clin Epidemiol 2021;135:17-28. https://doi.org/10.1016/j.jclinepi.2021.02.021
  15. Chen Y, Li L, Zhang Q, Liu H, Huang Y, Lin S, et al. Epidemiology, methodological quality, and reporting characteristics of systematic reviews and meta-analyses on coronavirus disease 2019: a cross-sectional study. Medicine (Baltimore) 2021;100(47):e27950. https://doi.org/10.1097/MD.0000000000027950
  16. Jones RC, Ho JC, Kearney H, Glibbery M, Levin DL, Kim J, et al. Evaluating trends in COVID-19 research activity in early 2020:the creation and utilization of a novel open-access database. Cureus 2020;12(8):e9943. https://doi.org/10.7759/cureus.9943
  17. Gurnani B, Kaur K. Analysis of COVID-19 publications in the Indian Journal of Ophthalmology during two years of the pandemic and their impact on ophthalmic literature. Indian J Ophthalmol 2022;70(5):1522-1532. https://doi.org/10.4103/ijo.IJO_2301_21
  18. Sofi-Mahmudi A, Raittio E. Transparency of COVID-19-related research in dental journals. Front Oral Health 2022;3:871033. https://doi.org/10.3389/froh.2022.871033
  19. Kim JM, Yoo JH, Cho HK, Hong ST. Analysis of PubMed and KoreaMed indexed Korean publications on COVID-19. J Korean Med Sci 2021;36(49):e345. https://doi.org/10.3346/jkms.2021.36.e345
  20. Low WY, Ng KH, Kabir MA, Koh AP, Sinnasamy J. Trend and impact of international collaboration in clinical medicine papers published in Malaysia. Scientometrics 2014;98(2):1521-1533. https://doi.org/10.1007/s11192-013-1121-6
  21. Leydesdorff L, Bornmann L, Wagner CS. The relative influences of government funding and international collaboration on citation impact. J Assoc Inf Sci Technol 2019;70(2):198-201. https://doi.org/10.1002/asi.24109
  22. Lundh A, Lexchin J, Mintzes B, Schroll JB, Bero L. Industry sponsorship and research outcome. Cochrane Database Syst Rev 2017;2(2):MR000033. https://doi.org/10.1002/14651858.MR000033.pub3
  23. von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 2008;61(4):344-349. https://doi.org/10.1016/j.jclinepi.2007.11.008
  24. Schulz KF, Altman DG, Moher D; CONSORT Group. CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMJ 2010;340:c332. https://doi.org/10.1136/bmj.c332
  25. Devereaux PJ, Yusuf S. The evolution of the randomized controlled trial and its role in evidence-based decision making. J Intern Med 2003;254(2):105-113. https://doi.org/10.1046/j.1365-2796.2003.01201.x