Advances in nano research

  • 제15권2호
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  • Pages.129-139
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  • 2023
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  • 2287-237X(pISSN)
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  • 2287-2388(eISSN)
테크노프레스 (Techno-Press)
권호 표지
DOI QR코드

DOI QR Code

Nano-medicine effectiveness in pediatric patients: An artificial intelligence investigation

  • Shaona Wang (Department of Pediatrics, Shengjing Hospital of China Medical University) ;
  • Fan Yang (Department of Pediatrics, Shengjing Hospital of China Medical University)
  • 투고 : 2022.04.15
  • 심사 : 2022.08.07
  • 발행 : 2023.08.25
⟨ 이전 논문 다음 논문 ⟩

초록

Emerge of nanotechnology has affected many aspects of our life and also triggers research studies in many fields. Nano-medicine are proven to be effective in encountering diseases. In the present study, aspects of the applications and effectiveness of nano-medicine in pediatrics patients are studied. In this regard, using experimental data of previous published researches, combination and dose of nano-medicines are optimized using response surface method and neural-fuzzy inference network. The input parameters of the selected multiple nano-medicines are dose and type and the output is the effectiveness of the combinations using IC50 parameter. A detailed parameter study is presented to observe effects of each inputs on the IC50. The results indicate that personalized scaling of nano-medicine is required in therapy of pediatric diseases such as cancers.

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참고문헌

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