Advances in nano research

Techno-Press (테크노프레스)
권호 표지
DOI QR코드

DOI QR Code

Nano-medicine effectiveness in pediatric patients: An artificial intelligence investigation

  • Shaona Wang (Department of Pediatrics, Shengjing Hospital of China Medical University) ;
  • Fan Yang (Department of Pediatrics, Shengjing Hospital of China Medical University)
  • Received : 2022.04.15
  • Accepted : 2022.08.07
  • Published : 2023.08.25
⟨ Previous Next ⟩

Abstract

Emerge of nanotechnology has affected many aspects of our life and also triggers research studies in many fields. Nano-medicine are proven to be effective in encountering diseases. In the present study, aspects of the applications and effectiveness of nano-medicine in pediatrics patients are studied. In this regard, using experimental data of previous published researches, combination and dose of nano-medicines are optimized using response surface method and neural-fuzzy inference network. The input parameters of the selected multiple nano-medicines are dose and type and the output is the effectiveness of the combinations using IC50 parameter. A detailed parameter study is presented to observe effects of each inputs on the IC50. The results indicate that personalized scaling of nano-medicine is required in therapy of pediatric diseases such as cancers.

Keywords

References

  1. Adamian, A., Safari, K.H., Sheikholeslami, M., Habibi, M., A-lFurjan, M. and Chen, G. (2020), "Critical temperature and frequency characteristics of GPLs-Reinforced composite doubly curved panel", Appl. Sci., 10(9), 3251. https://doi.org/10.3390/app10093251 
  2. Adir, O., Poley, M., Chen, G., Froim, S., Krinsky, N., Shklover, J., Shainsky-Roitman, J., Lammers, T. and Schroeder, A. (2020), "Integrating artificial intelligence and nanotechnology for precision cancer medicine", Adv. Mater.,32(13), 1901989. https://doi.org/10.1002/adma.201901989 
  3. Al-Furjan, M., Dehini, R., Khorami, M., Habibi, M. and won Jung, D. (2020a), "On the dynamics of the ultra-fast rotating cantilever orthotropic piezoelectric nanodisk based on nonlocal strain gradient theory", Compos. Struct., 112990. https://doi.org/10.1016/j.compstruct.2020.112990 
  4. Al-Furjan, M., Fereidouni, M., Habibi, M., Abd Ali, R., Ni, J. and Safarpour, M. (2020b), "Influence of in-plane loading on the vibrations of the fully symmetric mechanical systems via dynamic simulation and generalized differential quadrature framework", Eng. Comput., 1-23. https://doi.org/10.1007/s00366-020-01177-7 
  5. Al-Furjan, M., Fereidouni, M., Sedghiyan, D., Habibi, M. and won Jung, D. (2020c), "Three-dimensional frequency response of the CNT-Carbon-Fiber reinforced laminated circular/annular plates under initially stresses", Compos. Struct., 113146. https://doi.org/10.1016/j.compstruct.2020.113146 
  6. Al-Furjan, M., Habibi, M., won Jung, D., Sadeghi, S., Safarpour, H., Tounsi, A. and Chen, G. (2020d), "A computational framework for propagated waves in a sandwich doubly curved nanocomposite panel", Eng. Comput., 1-18. https://doi.org/10.1007/s00366-020-01130-8 
  7. Al-Furjan, M., Habibi, M., won Jung, D. and Safarpour, H. (2020e), "Vibrational characteristics of a higher-order laminated composite viscoelastic annular microplate via modified couple stress theory", Compos. Struct., 113152. https://doi.org/10.1016/j.compstruct.2020.113152 
  8. Al-Furjan, M., Habibi, M., Won Jung, D., Safarpour, H. and Safarpour, M. (2020f), "On the buckling of the polymer-CNT-fiber nanocomposite annular system under thermo-mechanical loads", Mech. Based Des. Struct., 1-21. https://doi.org/10.1080/15397734.2020.1830106 
  9. Al-Furjan, M., Moghadam, S.A., Dehini, R., Shan, L., Habibi, M. and Safarpour, H. (2020g), "Vibration control of a smart shell reinforced by graphene nanoplatelets under external load: Semi-numerical and finite element modeling", Thin Wall. Struct., 107242. https://doi.org/10.1016/j.tws.2020.107242 
  10. Al-Furjan, M., Oyarhossein, M.A., Habibi, M., Safarpour, H. and Jung, D.W. (2020h), "Frequency and critical angular velocity characteristics of rotary laminated cantilever microdisk via two-dimensional analysis", Thin Wall. Struct., 157, 107111. https://doi.org/10.1016/j.tws.2020.107111 
  11. Al-Furjan, M.S.H., Habibi, M., Ebrahimi, F., Mohammadi, K. and Safarpour, H. (2020i), "Wave dispersion characteristics of high-speed-rotating laminated nanocomposite cylindrical shells based on four continuum mechanics theories", Wave. Random Complex Med., 1-27. https://doi.org/10.1080/17455030.2020.1831099 
  12. Al-Furjan, M.S.H., Habibi, M., Jung, D.w., Sadeghi, S., Safarpour, H., Tounsi, A. and Chen, G. (2020j), "A computational framework for propagated waves in a sandwich doubly curved nanocomposite panel", Eng. Comput., 38(2), 1679-1696. https://doi.org/10.1007/s00366-020-01130-8 
  13. Alipour, M., Torabi, M.A., Sareban, M., Lashini, H., Sadeghi, E., Fazaeli, A., Habibi, M. and Hashemi, R. (2020), "Finite element and experimental method for analyzing the effects of martensite morphologies on the formability of DP steels", Mech. Based Des. Struct., 48(5), 525-541. https://doi.org/10.1080/15397734.2019.1633343 
  14. Amelirad, O. and Assempour, A. (2019), "Experimental and crystal plasticity evaluation of grain size effect on formability of austenitic stainless steel sheets", J. Manuf. Proc., 47 310-323. https://doi.org/10.1016/j.jmapro.2019.09.035 
  15. Amelirad, O. and Assempour, A. (2021), "Coupled continuum damage mechanics and crystal plasticity model and its application in damage evolution in polycrystalline aggregates", Eng. Comput., 1-15. https://doi.org/10.1007/s00366-021-01346-2 
  16. Bai, Y., Alzahrani, B., Baharom, S. and Habibi, M. (2020), "Semi-numerical simulation for vibrational responses of the viscoelastic imperfect annular system with honeycomb core under residual pressure", Eng. Comput., 1-26. https://doi.org/10.1007/s00366-020-01191-9 
  17. Cai, J., Zhao, J., Xiang, Y., Liu, J., Chen, G., Hu, Y. and Chen, J. (2020), "Can i trust you? Estimation models for e-bikers stop-go decision before amber light at urban intersection", J. Adv. Transp., 2020. https://doi.org/10.1155/2020/6678996 
  18. Casanola-Martin, G.M. and Pham-The, H. (2019), "Machine learning applications in nanomedicine and nanotoxicology: An overview", Int. J. Appl. Nanotech. Res., 4(1), 1-7. https://doi.org/10.4018/IJANR.2019010101 
  19. Cavaleri, L., Chatzarakis, G.E., Di Trapani, F., Douvika, M.G., Roinos, K., Vaxevanidis, N.M. and Asteris, P.G. (2017), "Modeling of surface roughness in electro-discharge machining using artificial neural networks", Adv. Mater. Res., 6(2), 169. https://doi.org/10.12989/amr.2017.6.2.169 
  20. Cellot, G., Franceschi Biagioni, A. and Ballerini, L. (2021), "Nanomedicine and graphene-based materials: advanced technologies for potential treatments of diseases in the developing nervous system", Pediatr. Res., 92(1), 71-79. https://doi.org/10.1038/s41390-021-01681-6 
  21. Chen, F., Chen, J., Duan, R., Habibi, M. and Khadimallah, M.A. (2022), "Investigation on dynamic stability and aeroelastic characteristics of composite curved pipes with any yawed angle", Compos. Struct., 115195. https://doi.org/10.1016/j.compstruct.2022.115195 
  22. Cheshmeh, E., Karbon, M., Eyvazian, A., Jung, D.w., Habibi, M. and Safarpour, M. (2020), "Buckling and vibration analysis of FG-CNTRC plate subjected to thermo-mechanical load based on higher order shear deformation theory", Mech. Based Des. Struct., 1-24. https://doi.org/10.1080/15397734.2020.1744005 
  23. Dai, H. and Safarpour, H. (2021), "Frequency and thermal buckling information of laminated composite doubly curved open nanoshell", Adv. Nano Res., 10(1), 1-14. https://doi.org/10.12989/anr.2021.10.1.001 
  24. Dai, Z., Jiang, Z., Zhang, L. and Habibi, M. (2021a), "Frequency characteristics and sensitivity analysis of a size-dependent laminated nanoshell", Adv. Nano Res., 10(2), 175. https://doi.org/10.12989/anr.2021.10.2.175 
  25. Dai, Z., Zhang, L., Bolandi, S.Y. and Habibi, M. (2021b), "On the vibrations of the non-polynomial viscoelastic composite open-type shell under residual stresses", Compos. Struct., 113599. https://doi.org/10.1016/j.compstruct.2021.113599 
  26. De Lazaro, I. and Mooney, D.J. (2021), "Obstacles and opportunities in a forward vision for cancer nanomedicine", Nature Mater., 20(11), 1469-1479. https://doi.org/10.1038/s41563-021-01047-7 
  27. Dong, Y., Gao, Y., Zhu, Q., Moradi, Z. and Safa, M. (2022), "TEGDQE implementation to investigate the vibration of FG composite conical shells considering a frequency controller solid ring", Eng. Anal. Bound. Elem., 138, 95-107. https://doi.org/10.1016/j.enganabound.2022.01.017 
  28. Ebrahimi, F., Habibi, M. and Safarpour, H. (2019a), "On modeling of wave propagation in a thermally affected GNP-reinforced imperfect nanocomposite shell", Eng. Comput., 35(4), 1375-1389. https://doi.org/10.1007/s00366-018-0669-4 
  29. Ebrahimi, F., Hajilak, Z.E., Habibi, M. and Safarpour, H. (2019b), "Buckling and vibration characteristics of a carbon nanotubere-inforced spinning cantilever cylindrical 3D shell conveying viscous fluid flow and carrying spring-mass systems under various temperature distributions", Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, 233(13), 4590-4605. https://doi.org/10.1177/0954406219832323 
  30. Ebrahimi, F., Hashemabadi, D., Habibi, M. and Safarpour, H. (2020a), "Thermal buckling and forced vibration characteristics of a porous GNP reinforced nanocomposite cylindrical shell", Microsyst. Technol., 26(2), 461-473. https://doi.org/10.1007/s00542-019-04542-9 
  31. Ebrahimi, F., Mohammadi, K., Barouti, M.M. and Habibi, M. (2019c), "Wave propagation analysis of a spinning porous graphene nanoplatelet-reinforced nanoshell", Wave. Random Complex Med., 1-27. https://doi.org/10.1080/17455030.2019.1694729 
  32. Ebrahimi, F., Supeni, E.E.B., Habibi, M. and Safarpour, H. (2020b), "Frequency characteristics of a GPL-reinforced composite microdisk coupled with a piezoelectric layer", Eur. Phys. J. Plus, 135(2), 144. https://doi.org/10.1140/epjp/s13360-020-00217-x 
  33. Esmailpoor Hajilak, Z., Pourghader, J., Hashemabadi, D., Sharifi Bagh, F., Habibi, M. and Safarpour, H. (2019), "Multilayer GPLRC composite cylindrical nanoshell using modified strain gradient theory", Mech. Based Des. Struct., 47(5), 521-545. https://doi/10.1080/15397734.2019.1566743 
  34. Fan, L., Huang, Y., Ji, D., Moradi, Z., Safa, M. and Amine Khadimallah, M. (2022), "Interaction of angular velocity and temperature rise in the thermo-inertia bifurcation buckling of FG laminated nanocomposite annular plates", Eng. Struct., 265, 114518. https://doi.org/10.1016/j.engstruct.2022.114518 
  35. Fjodorova, N., Novic, M., Gajewicz, A. and Rasulev, B. (2017), "The way to cover prediction for cytotoxicity for all existing nano-sized metal oxides by using neural network method", Nanotoxicology, 11(4), 475-483. http://doi.org/10.1080/17435390.2017.1310949 
  36. Forsat, M., Musharavati, F., Eltai, E., Zain, A.M., Mobayen, S. and Mohamed, A.M. (2021), "Vibration characteristics of microplates with GNPs-reinforced epoxy core bonded to piezoelectric-reinforced CNTs patches", Adv. Nano Res., 11(2), 115-140. https://doi.org/10.12989/anr.2021.11.2.115 
  37. Gao, H., Hsu, P.H., Li, K. and Zhang, J. (2020), "The real effect of smoking bans: Evidence from corporate innovation", J. Financ. Quant. Anal., 55(2), 387-427. https://doi.org/10.1017/S0022109018001564 
  38. Ghamkhar, M., Khadimallah, M.A., Iqbal, M.Z., Hussain, M., Yahya, A., Khedher, K.M., Naeem, M.N. and Tounsi, A. (2021), "Performance of FGM bilayered cylindrical shell placed on cantilever edge", Adv. Nano Res., 11(4), 339-345. https://doi.org/10.12989/anr.2021.11.4.339 
  39. Ghazanfari, A., Soleimani, S.S., Keshavarzzadeh, M., Habibi, M., Assempuor, A. and Hashemi, R. (2020), "Prediction of FLD for sheet metal by considering through-thickness shear stresses", Mech. Based Des. Struct., 48(6), 755-772. https://doi.org/10.1080/15397734.2019.1662310 
  40. Guido, C., Baldari, C., Maiorano, G., Mastronuzzi, A., Carai, A., Quintarelli, C., De Angelis, B., Cortese, B., Gigli, G. and Palama, I.E. (2022), "Nanoparticles for diagnosis and target therapy in pediatric brain cancers", Diagnostics, 12(1), 173. https://doi.org/10.3390/diagnostics12010173 
  41. Guo, J., Baharvand, A., Tazeddinova, D., Habibi, M., Safarpour, H., Roco-Videla, A. and Selmi, A. (2021a), "An intelligent computer method for vibration responses of the spinning multi-layer symmetric nanosystem using multi-physics modeling", Eng. Comput., 1-22. https://doi.org/10.1007/s00366-021-01433-4 
  42. Guo, Y., Mi, H. and Habibi, M. (2021b), "Electromechanical energy absorption, resonance frequency, and low-velocity impact analysis of the piezoelectric doubly curved system", Mech. Syst. Signal Pr., 157, 107723. https://doi.org/10.1016/j.ymssp.2021.107723 
  43. Habibi, M., Darabi, R., Sa, J.C.d. and Reis, A. (2021), "An innovation in finite element simulation via crystal plasticity assessment of grain morphology effect on sheet metal formability", Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications, 235(8), 1937-1951. https://doi.org/10.1177/14644207211024686 
  44. Habibi, M., Ghazanfari, A., Assempour, A., Naghdabadi, R. and Hashemi, R. (2017), "Determination of forming limit diagram using two modified finite element models", Mech Eng. 48(4), 141-144. https://doi.org/10.22060/MEJ.2016.664 
  45. Habibi, M., Hashemabadi, D. and Safarpour, H. (2019a), "Vibration analysis of a high-speed rotating GPLRC nanostructure coupled with a piezoelectric actuator", Eur. Phys. J. Plus, 134(6), 307. https://doi.org/10.1140/epjp/i2019-12742-7 
  46. Habibi, M., Hashemi, R., Ghazanfari, A., Naghdabadi, R. and Assempour, A. (2018a), "Forming limit diagrams by including the M-K model in finite element simulation considering the effect of bending", Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications, 232(8), 625-636.  https://doi.org/10.1177/1464420716642258
  47. Habibi, M., Hashemi, R., Sadeghi, E., Fazaeli, A., Ghazanfari, A. and Lashini, H. (2016), "Enhancing the mechanical properties and formability of low carbon steel with dual-phase microstructures", J. Mater. Eng. Perform., 25(2), 382-389. https://doi.org/10.1007/s11665-016-1882-1. 
  48. Habibi, M., Hashemi, R., Tafti, M.F. and Assempour, A. (2018b), "Experimental investigation of mechanical properties, formability and forming limit diagrams for tailor-welded blanks produced by friction stir welding", J. Manuf. Proc., 31, 310-323. https://doi.org/10.1016/j.jmapro.2017.11.009 
  49. Habibi, M., Mohammadgholiha, M. and Safarpour, H. (2019b), "Wave propagation characteristics of the electrically GNP-reinforced nanocomposite cylindrical shell", J. Brazil. Soc. Mech. Sci. Eng., 41(5), 221. https://doi.org/10.1007/s40430-019-1715-x 
  50. Habibi, M., Mohammadi, A., Safarpour, H. and Ghadiri, M. (2019c), "Effect of porosity on buckling and vibrational characteristics of the imperfect GPLRC composite nanoshell", Mech. Based Des. Struct., 1-30. https://doi.org/10.1080/15397734.2019.1701490 
  51. Habibi, M., Mohammadi, A., Safarpour, H., Shavalipour, A. and Ghadiri, M. (2019d), "Wave propagation analysis of the laminated cylindrical nanoshell coupled with a piezoelectric actuator", Mech. Based Des. Struct., 1-19. https://doi.org/10.1080/15397734.2019.1697932 
  52. Habibi, M., Safarpour, M. and Safarpour, H. (2020), "Vibrational characteristics of a FG-GPLRC viscoelastic thick annular plate using fourth-order Runge-Kutta and GDQ methods", Mech. Based Des. Struct., 1-22. https://doi.org/10.1080/15397734.2020.1779086 
  53. Habibi, M., Taghdir, A. and Safarpour, H. (2019e), "Stability analysis of an electrically cylindrical nanoshell reinforced with graphene nanoplatelets", Compos. Part B Eng., 175, 107125. https://doi.org/10.1016/j.compositesb.2019.107125 
  54. Hashemi, H.R., Alizadeh, A.a., Oyarhossein, M.A., Shavalipour, A., Makkiabadi, M. and Habibi, M. (2019), "Influence of imperfection on amplitude and resonance frequency of a reinforcement compositionally graded nanostructure", Wave. Random Complex Med., 1-27. https://doi.org/10.1080/17455030.2019.1662968 
  55. Hayat, H., Nukala, A., Nyamira, A., Fan, J. and Wang, P. (2021), "A concise review: The synergy between artificial intelligence and biomedical nanomaterials that empowers nanomedicine", Biomed. Mater., 16(5), 052001. https://doi.org/10.1088/1748-605x/ac15b2 
  56. He, X., Ding, J., Habibi, M., Safarpour, H. and Safarpour, M. (2021), "Non-polynomial framework for bending responses of the multi-scale hybrid laminated nanocomposite reinforced circular/annular plate", Thin Wall. Struct., 166, 108019. https://doi.org/10.1016/j.tws.2021.108019 
  57. Ho, D., Wang, P. and Kee, T. (2019), "Artificial intelligence in nanomedicine", Nanosc. Horizons, 4(2), 365-377. https://doi.org/10.1039/C8NH00233A 
  58. Hou, F., Wu, S., Moradi, Z. and Shafiei, N. (2021), "The computational modeling for the static analysis of axially functionally graded micro-cylindrical imperfect beam applying the computer simulation", Eng. Comput., 1-19. https://doi.org/10.1007/s00366-021-01456-x 
  59. Hou, Q., Huang, J., Xiong, X., Guo, Y. and Zhang, B. (2022), "Role of nutrient-sensing receptor GPRC6A in regulating colonic group 3 innate lymphoid cells and inflamed mucosal healing", J. Crohn's Colitis, 20, 1-13. https://doi.org/10.1002/adfm.202202470 
  60. Huang, X., Hao, H., Oslub, K., Habibi, M. and Tounsi, A. (2021a), "Dynamic stability/instability simulation of the rotary size-dependent functionally graded microsystem", Eng. Comput., 1-17. https://doi.org/10.1007/s00366-021-01399-3 
  61. Huang, X., Zhang, Y., Moradi, Z. and Shafiei, N. (2021b), "Computer simulation via a couple of homotopy perturbation methods and the generalized differential quadrature method for nonlinear vibration of functionally graded non-uniform microtube", Eng. Comput., 1-18. https://doi.org/10.1007/s00366-021-01395-7 
  62. Huang, X., Zhu, Y., Vafaei, P., Moradi, Z. and Davoudi, M. (2021c), "An iterative simulation algorithm for large oscillation of the applicable 2D-electrical system on a complex nonlinear substrate", Eng. Comput., 38(Suppl 4), 3217-3235. https://doi.org/10.1007/s00366-021-01320-y 
  63. Jang, J.R. (1993), "ANFIS: Adaptive-network-based fuzzy inference system", IEEE T. Syst. Man Cybernet., 23(3), 665-685. https://doi.org/10.1109/21.256541 
  64. Jiao, J., Ghoreishi, S.M., Moradi, Z. and Oslub, K. (2021), "Coupled particle swarm optimization method with genetic algorithm for the static-dynamic performance of the magneto-electro-elastic nanosystem", Eng. Comput., 1-15. https://doi.org/10.1007/s00366-021-01391-x 
  65. Jin, H.-Y. and Wang, Z.-A. (2019), "Global stabilization of the full attraction-repulsion Keller-Segel system", arXiv preprint arXiv:1905.05990. https://doi.org/10.3934/dcds.2020027 
  66. Jin, K., Yan, Y., Chen, M., Wang, J., Pan, X., Liu, X., Liu, M., Lou, L., Wang, Y. and Ye, J. (2022), "Multimodal deep learning with feature level fusion for identification of choroidal neovascularization activity in age-related macular degeneration", Acta Ophthalmol., 100(2), e512-e520. https://doi.org/10.1111/aos.14928 
  67. Kar, S., Pathakoti, K., Tchounwou, P.B., Leszczynska, D. and Leszczynski, J. (2021), "Evaluating the cytotoxicity of a large pool of metal oxide nanoparticles to Escherichia coli: Mechanistic understanding through In Vitro and In Silico studies", Chemosphere, 264, 128428. https://doi.org/10.1016/j.chemosphere.2020.128428 
  68. Khadimallah, M.A., Hussain, M., Naeem, M.N., Taj, M. and Tounsi, A. (2021a), "Monitoring and control of multiple fraction laws with ring based composite structure", Adv. Nano Res., 10(2), 129-138. https://doi.org/10.12989/anr.2021.10.2.129 
  69. Khadimallah, M.A., Hussain, M., Taj, M., Ayed, H. and Tounsi, A. (2021b), "Parametric vibration analysis of single-walled carbon nanotubes based on Sanders shell theory", Adv. Nano Res., 10(2), 165-174. https://doi.org/10.12989/anr.2021.10.2.165 
  70. Kim, B.Y.S., Rutka, J.T. and Chan, W.C.W. (2010), "Nanomedicine", New England J. Med., 363(25), 2434-2443. https://doi.org/10.1056/NEJMra0912273 
  71. Kong, F., Dong, F., Duan, M., Habibi, M., Safarpour, H. and Tounsi, A. (2022), "On the vibrations of the Electrorheological sandwich disk with composite face sheets considering pre and post-yield regions", Thin Wall. Struct., 179, 109631. https://doi.org/10.1016/j.tws.2022.109631 
  72. Kumar, Y., Gupta, A. and Tounsi, A. (2021), "Size-dependent vibration response of porous graded nanostructure with FEM and nonlocal continuum model", Adv. Nano Res., 11(1), 1-17.
  73. Lee, H. (2021), "Molecular modeling of protein corona formation and its interactions with nanoparticles and cell membranes for nanomedicine applications", Pharmaceutics, 13(5), 637. https://doi.org/10.3390/pharmaceutics13050637 
  74. Li, H. and Wang, F. (2021), "Core-shell chitosan microsphere with antimicrobial and vascularized functions for promoting skin wound healing", Mater. Des., 204, 109683. https://doi.org/10.1016/j.matdes.2021.109683 
  75. Li, J., Tang, F. and Habibi, M. (2020a), "Bi-directional thermal buckling and resonance frequency characteristics of a GNP-reinforced composite nanostructure", Eng. Comput., 1-22. https://doi.org/10.1007/s00366-020-01110-y 
  76. Li, Y., Li, S., Guo, K., Fang, X. and Habibi, M. (2020b), "On the modeling of bending responses of graphene-reinforced higher order annular plate via two-dimensional continuum mechanics approach", Eng. Comput., 1-22. https://doi.org/10.1007/s00366-020-01166-w 
  77. Liu, H., Shen, S., Oslub, K., Habibi, M. and Safarpour, H. (2021a), "Amplitude motion and frequency simulation of a composite viscoelastic microsystem within modified couple stress elasticity", Eng. Comput., 1-15. https://doi.org/10.1007/s00366-021-01316-8 
  78. Liu, H., Zhao, Y., Pishbin, M., Habibi, M., Bashir, M. and Issakhov, A. (2021b), "A comprehensive mathematical simulation of the composite size-dependent rotary 3D microsystem via two-dimensional generalized differential quadrature method", Eng. Comput., 1-16. https://doi.org/10.1007/s00366-021-01419-2 
  79. Liu, K., Ke, F., Huang, X., Yu, R., Lin, F., Wu, Y. and Ng, D.W.K. (2021c), "Deepban: A temporal convolution-based communication framework for dynamic WBANS", IEEE T. Commun., 69(10), 6675-6690. https://doi.org/10.1109/TCOMM.2021.3094581 
  80. Liu, L., Bi, M., Wang, Y., Liu, J., Jiang, X., Xu, Z. and Zhang, X. (2021d), "Artificial intelligence-powered microfluidics for nanomedicine and materials synthesis", Nanoscale, 13(46), 19352-19366. https://doi.org/10.1039/D1NR06195J 
  81. Liu, L., Li, B., Gotting, G., Xiang, Y., Salem, Q., Hamid, M. and Xie, J. (2020a). "Loss minimization of traction systems in battery electric vehicles using variable dc-link voltage technique-experimental study", 2020 22nd European Conference on Power Electronics and Applications (EPE'20 ECCE Europe), Lyon, France, September. 
  82. Liu, L., Zhang, Z., Cao, L., Xiong, Z., Tang, Y. and Pan, Y. (2021e), "Cytotoxicity of phytosynthesized silver nanoparticles: A meta-analysis by machine learning algorithms", Sust. Chem. Pharm., 21, 100425. https://doi.org/10.1016/j.scp.2021.100425 
  83. Liu, Y., Qiao, J., Hu, Y., Fang, T., Xu, T., Xiang, Y. and Han, Y. (2020b), "Determination of curve speed zones for mountainous freeways", Math. Probl. Eng., 2020. https://doi.org/10.1155/2020/8844004 
  84. Liu, Y., Wang, W., He, T., Moradi, Z. and Larco Benitez, M.A. (2021f), "On the modelling of the vibration behaviors via discrete singular convolution method for a high-order sector annular system", Eng. Comput., 38(Suppl 4), 3631-3653. https://doi.org/10.1007/s00366-021-01454-z 
  85. Liu, Z., Su, S., Xi, D. and Habibi, M. (2020c), "Vibrational responses of a MHC viscoelastic thick annular plate in thermal environment using GDQ method", Mech. Based Des. Struct., 1-26. https://doi.org/10.1080/15397734.2020.1784201 
  86. Liu, Z., Wu, X., Yu, M. and Habibi, M. (2020d), "Large-amplitude dynamical behavior of multilayer graphene platelets reinforced nanocomposite annular plate under thermo-mechanical loadings", Mech. Based Des. Struct., 1-25. https://doi.org/10.1080/15397734.2020.1815544 
  87. Lori, E.S., Ebrahimi, F., Supeni, E.E.B., Habibi, M. and Safarpour, H. (2020), "The critical voltage of a GPL-reinforced composite microdisk covered with piezoelectric layer", Eng. Comput., 1-20. https://doi.org/10.1007/s00366-020-01004-z 
  88. Lu, J., Li, D., Wang, P., Zheng, F. and Wang, M. (2022), "Security-aware routing protocol based on artificial neural network algorithm and 6LoWPAN in the internet of things", Wireless Commun. Mobile Comput., 2022. https://doi.org/10.1155/2022/8374473 
  89. Luo, J., Song, J., Moradi, Z., Safa, M. and Khadimallah, M.A. (2022a), "Effect of simultaneous compressive and inertia loads on the bifurcation stability of shear deformable functionally graded annular fabrications reinforced with graphenes", Eur. J. Mech.A Solids, 104581. https://doi.org/10.1016/j.euromechsol.2022.104581 
  90. Luo, J., Wu, S., Hou, S., Moradi, Z., Habibi, M. and Khadimallah, M.A. (2022b), "Thermally nonlinear thermoelasticity of a one-dimensional finite domain based on the finite strain concept", Eur. J. Mech. A Solids. 104726. https://doi.org/10.1016/j.euromechsol.2022.104726 
  91. Ma, L., Liu, X. and Moradi, Z. (2022), "On the chaotic behavior of graphene-reinforced annular systems under harmonic excitation", Eng. Comput., 1-25. https://doi.org/10.1007/s00366-020-01210-9 
  92. Madenci, E. (2021), "Free vibration analysis of carbon nanotube RC nanobeams with variational approaches", Adv. Nano Res., 11(2), 157-171. https://doi.org/10.12989/anr.2021.11.2.157 
  93. Maojo, V., Martin-Sanchez, F., Kulikowski, C., Rodriguez-Paton, A. and Fritts, M. (2010), "Nanoinformatics and DNA-based computing: catalyzing nanomedicine", Pediatr. Res., 67(5), 481-489. https://doi.org/10.1203/PDR.0b013e3181d6245e 
  94. Michael, M., Meyyazhagan, A., Velayudhannair, K., Pappuswamy, M., Maria, A., Xavier, V., Balasubramanian, B., Baskaran, R., Kamyab, H. and Vasseghian, Y. (2022), "The content of heavy metals in cigarettes and the impact of their leachates on the aquatic ecosystem", Sustainability. 14(8), 4752. https://doi.org/10.3390/su14084752 
  95. Moayedi, H., Aliakbarlou, H., Jebeli, M., Noormohammadiarani, O., Habibi, M., Safarpour, H. and Foong, L. (2020a), "Thermal buckling responses of a graphene reinforced composite micropanel structure", Int. J. Appl. Mech., 12(1), 2050010. https://doi.org/10.1142/S1758825120500106 
  96. Moayedi, H., Ebrahimi, F., Habibi, M., Safarpour, H. and Foong, L.K. (2020b), "Application of nonlocal strain-stress gradient theory and GDQEM for thermo-vibration responses of a laminated composite nanoshell", Eng. Comput., 1-16. https://doi.org/10.1007/s00366-020-01002-1 
  97. Moayedi, H., Habibi, M., Safarpour, H., Safarpour, M. and Foong, L. (2019), "Buckling and frequency responses of a graphene nanoplatelet reinforced composite microdisk", Int. J. Appl. Mech., 11(10), 1950102. https://doi.org/10.1142/S1758825119501023 
  98. Mohammadgholiha, M., Shokrgozar, A., Habibi, M. and Safarpour, H. (2019), "Buckling and frequency analysis of the nonlocal strain-stress gradient shell reinforced with graphene nanoplatelets", J. Vib. Control, 25(19-20), 2627-2640. https://doi.org/10.1177/1077546319863251 
  99. Mohammadi, A., Lashini, H., Habibi, M. and Safarpour, H. (2019), "Influence of viscoelastic foundation on dynamic behaviour of the double walled cylindrical inhomogeneous micro shell using MCST and with the aid of GDQM", J. Solid Mech., 11(2), 440-453. https://doi.org/10.22034/JSM.2019.665264 
  100. Moradi Kashkooli, F., Soltani, M., Souri, M., Meaney, C. and Kohandel, M. (2021), "Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine", Nano Today, 36, 101057. https://doi.org/10.1016/j.nantod.2020.101057 
  101. Moradi, Z., Davoudi, M., Ebrahimi, F. and Ehyaei, A.F. (2021), "Intelligent wave dispersion control of an inhomogeneous micro-shell using a proportional-derivative smart controller", Wave. Random Complex Med., 1-24. https://doi.org/10.1080/17455030.2021.1926572 
  102. Najaafi, N., Jamali, M., Habibi, M., Sadeghi, S., Jung, D.w. and Nabipour, N. (2020), "Dynamic instability responses of the substructure living biological cells in the cytoplasm environment using stress-strain size-dependent theory", J. Biomol. Struct. Dyn., 1-12. https://doi.org/10.1080/07391102.2020.1751297 
  103. Nieto Gonzalez, N., Obinu, A., Rassu, G., Giunchedi, P. and Gavini, E. (2021), "Polymeric and Lipid Nanoparticles: Which Applications in Pediatrics?", Pharmaceutics. 13(5), 670. https://doi.org/10.3390/pharmaceutics13050670 
  104. Oyarhossein, M.A., Alizadeh, A.a., Habibi, M., Makkiabadi, M., Daman, M., Safarpour, H. and Jung, D.W. (2020), "Dynamic response of the nonlocal strain-stress gradient in laminated polymer composites microtubes", Sci. Rep., 10(1), 1-19. https://doi.org/10.1038/s41598-020-61855-w 
  105. Pourjabari, A., Hajilak, Z.E., Mohammadi, A., Habibi, M. and Safarpour, H. (2019), "Effect of porosity on free and forced vibration characteristics of the GPL reinforcement composite nanostructures", Comput. Math. Appl., 77(10), 2608-2626. https://doi.org/10.1016/j.camwa.2018.12.041 
  106. Rashid, M.B.M.A., Toh, T.B., Hooi, L., Silva, A., Zhang, Y., Tan, P.F., Teh, A.L., Karnani, N., Jha, S., Ho, C.M., Chng, W.J., Ho, D. and Chow, E.K.H. (2018), "Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP)", Sci. Transl. Med., 10(453), eaan0941. https://doi.org/10.1126/scitranslmed.aan0941 
  107. Safarpour, H., Ghanizadeh, S.A. and Habibi, M. (2018), "Wave propagation characteristics of a cylindrical laminated composite nanoshell in thermal environment based on the nonlocal strain gradient theory", Eur. Phys. J. Plus, 133(12), 532. https://doi.org/10.1140/epjp/i2018-12385-2 
  108. Safarpour, H., Hajilak, Z.E. and Habibi, M. (2019a), "A size-dependent exact theory for thermal buckling, free and forced vibration analysis of temperature dependent FG multilayer GPLRC composite nanostructures restring on elastic foundation", Int. J. Mech. Mater. Des., 15(3), 569-583. https://doi.org/10.1007/s10999-018-9431-8 
  109. Safarpour, H., Pourghader, J. and Habibi, M. (2019b), "Influence of spring-mass systems on frequency behavior and critical voltage of a high-speed rotating cantilever cylindrical three-dimensional shell coupled with piezoelectric actuator", J. Vib. Control, 25(9), 1543-1557. https://doi.org/10.1177/1077546319828465 
  110. Safarpour, M., Ebrahimi, F., Habibi, M. and Safarpour, H. (2020), "On the nonlinear dynamics of a multi-scale hybrid nanocomposite disk", Eng. Comput., 1-20. https://doi.org/10.1007/s00366-020-00949-5 
  111. Serov, N. and Vinogradov, V. (2022), "Artificial intelligence to bring nanomedicine to life", Adv. Drug Deliv. Rev., 184, 114194. https://doi.org/10.1016/j.addr.2022.114194 
  112. Shao, Y., Zhao, Y., Gao, J. and Habibi, M. (2021), "Energy absorption of the strengthened viscoelastic multi-curved composite panel under friction force", Arch. Civil Mech. Eng., 21(4), 1-29. https://doi.org/10.1007/s43452-021-00279-3 
  113. Shariati, A., Habibi, M., Tounsi, A., Safarpour, H. and Safa, M. (2020a), "Application of exact continuum size-dependent theory for stability and frequency analysis of a curved cantilevered microtubule by considering viscoelastic properties", Eng. Comput., 1-20. https://doi.org/10.1007/s00366-020-01024-9 
  114. Shariati, A., Mohammad-Sedighi, H., Zur, K.K., Habibi, M. and Safa, M. (2020b), "On the vibrations and stability of moving viscoelastic axially functionally graded nanobeams", Materials, 13(7), 1707. https://doi.org/10.3390/ma13071707 
  115. Shariati, A., Mohammad-Sedighi, H., Zur, K.K., Habibi, M. and Safa, M. (2020c), "Stability and dynamics of viscoelastic moving rayleigh beams with an asymmetrical distribution of material parameters", Symmetry, 12(4), 586. https://doi.org/10.3390/sym12040586 
  116. Shokrgozar, A., Safarpour, H. and Habibi, M. (2020), "Influence of system parameters on buckling and frequency analysis of a spinning cantilever cylindrical 3D shell coupled with piezoelectric actuator", Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, 234(2), 512-529. https://doi.org/10.1177/0954406219883312 
  117. Silva, M., Ferreira, F.N., Alves, N.M. and Paiva, M.C. (2020), "Biodegradable polymer nanocomposites for ligament/tendon tissue engineering", J. Nanobiotech., 18(1), 23. https://doi.org/10.1186/s12951-019-0556-1 
  118. Singh, A.V., Ansari, M.H.D., Rosenkranz, D., Maharjan, R.S., Kriegel, F.L., Gandhi, K., Kanase, A., Singh, R., Laux, P. and Luch, A. (2020a), "Artificial intelligence and machine learning in computational nanotoxicology: Unlocking and empowering nanomedicine", Adv. Healthcare Mater., 9(17), 1901862. https://doi.org/10.1002/adhm.201901862 
  119. Singh, A.V., Rosenkranz, D., Ansari, M.H.D., Singh, R., Kanase, A., Singh, S.P., Johnston, B., Tentschert, J., Laux, P. and Luch, A. (2020b), "Artificial intelligence and machine learning empower advanced biomedical material design to toxicity prediction", Adv. Intell. Syst., 2(12), 2000084. https://doi.org/10.1002/aisy.202000084 
  120. Sunoqrot, S. and Abujamous, L. (2019), "pH-sensitive polymeric nanoparticles of quercetin as a potential colon cancer-targeted nanomedicine", J. Drug Deliv. Sci. Technol., 52, 670-676. https://doi.org/10.1016/j.jddst.2019.05.035 
  121. Tlidji, Y., Benferhat, R., Trinh, L.C., Tahar, H.D. and Abdelouahed, T. (2021), "New state-space approach to dynamic analysis of porous FG beam under different boundary conditions", Adv. Nano Res., 11(4), 347-359. https://doi.org/10.12989/anr.2021.11.4.347 
  122. Wang, H., Habibi, M., Marzouki, R., Majdi, A., Shariati, M., Denic, N., Zakic, A., Khorami, M., Khadimallah, M.A. and Ebid, A.A.K. (2022a), "Improving the self-healing of cementitious materials with a hydrogel system", Gels, 8(5), 278. https://doi.org/10.3390/gels8050278 
  123. Wang, P., Gao, Z., Pan, F., Moradi, Z., Mahmoudi, T. and Khadimallah, M.A. (2022b), "A couple of GDQM and iteration techniques for the linear and nonlinear buckling of bi-directional functionally graded nanotubes based on the nonlocal strain gradient theory and high-order beam theory", Eng. Anal. Bound. Elem., 143, 124-136. https://doi.org/10.1016/j.enganabound.2022.06.007 
  124. Wang, Y., Yang, J., Moradi, Z., Safa, M. and Khadimallah, M.A. (2022c), "Nonlinear dynamic analysis of thermally deformed beams subjected to uniform loading resting on nonlinear viscoelastic foundation", Eur. J. Mech. A Solids, 95, 104638. https://doi.org/10.1016/j.euromechsol.2022.104638 
  125. Wang, Z., Yu, S., Xiao, Z. and Habibi, M. (2020), "Frequency and buckling responses of a high-speed rotating fiber metal laminated cantilevered microdisk", Mech. Adv. Mater. Struct., 1-14. https://doi.org/10.1080/15376494.2020.1824284 
  126. Wu, J. and Habibi, M. (2021), "Dynamic simulation of the ultra-fast-rotating sandwich cantilever disk via finite element and semi-numerical methods", Eng. Comput., 1-17. https://doi.org/10.1007/s00366-021-01396-6 
  127. Xia, W., Du, J., Habibi, M., Shariati, M. and Khadimallah, M.A. (2022), "Application of Chebyshev-based GDQ and Newmark methods to viscothermoelasticity responses of FG composite annular systems", Eng. Anal. Bound. Elem., 143, 28-42. https://doi.org/10.1016/j.enganabound.2022.06.003 
  128. Xiang, Y. (2022), AI and IoT Meet Mobile Machines: Towards a Smart Working Site, KIT Scientific Publishing. 
  129. Xiang, Y., Li, D., Su, T., Zhou, Q., Brach, C., Mao, S.S. and Geimer, M. (2022a), "Where am I? SLAM for mobile machines on a smart working site", Vehicles, 4(2), 529-552. https://doi.org/10.3390/vehicles4020031 
  130. Xiang, Y., Li, R., Brach, C., Liu, X. and Geimer, M. (2022b), "A novel algorithm for hydrostatic-mechanical mobile machines with a dual-clutch transmission", Energies, 15(6), 2095. https://doi.org/10.3390/en15062095 
  131. Xiang, Y., Liu, K., Su, T., Li, J., Ouyang, S., Mao, S.S. and Geimer, M. (2021a), "An extension of BIM using AI: A multi working-machines pathfinding solution", IEEE Access, 9, 124583-124599. https://doi.org/10.1109/ACCESS.2021.3110937 
  132. Xiang, Y., Xu, B., Su, T., Brach, C., Mao, S.S. and Geimer, M. (2021b). "5G meets construction machines: Towards a smart working site", 2021 International Conference on Computing and Communications Applications and Technologies (I3CAT). 
  133. Xiong, Q.M., Chen, Z., Huang, J.T., Zhang, M., Song, H., Hou, X.F., Li, X.B. and Feng, Z.J. (2020), "Preparation, structure and mechanical properties of Sialon ceramics by transition metal-catalyzed nitriding reaction", Rare Metals, 39(5), 589-596.  https://doi.org/10.1007/s12598-020-01385-6
  134. Xu, W., Pan, G., Moradi, Z. and Shafiei, N. (2021), "Nonlinear forced vibration analysis of functionally graded non-uniform cylindrical microbeams applying the semi-analytical solution", Compos. Struct., 114395. https://doi.org/10.1016/j.compstruct.2021.114395 
  135. Xue, X., Zhang, H., Liu, H., Wang, S., Li, J., Zhou, Q., Chen, X., Ren, X., Jing, Y. and Deng, Y. (2022), "Rational design of multifunctional CuS nanoparticle-PEG composite soft hydrogel-coated 3D hard polycaprolactone scaffolds for efficient bone regeneration", Adv. Funct. Mater., 2202470. https://doi.org/10.1002/adfm.202202470 
  136. Yang, N., Moradi, Z., Arvin, H., Muhsen, S. and Khadimallah, M.A. (2022a), "A study on small scale thermal dynamic instability of rotating GPL-reinforced microbeams under principal parametric resonance stimulation of axial and transversal modes regarding the proportional damping", Thin Wall. Struct., 180, 109806. https://doi.org/10.1016/j.tws.2022.109806 
  137. Yang, N., Moradi, Z., Khadimallah, M.A. and Arvin, H. (2022b), "Application of the Chebyshev-Ritz route in determination of the dynamic instability region boundary for rotating nanocomposite beams reinforced with graphene platelet subjected to a temperature increment", Eng. Anal. Bound. Elem., 139, 169-179. https://doi.org/10.1016/j.enganabound.2022.03.013 
  138. Yu, X., Maalla, A. and Moradi, Z. (2022), "Electroelastic high-order computational continuum strategy for critical voltage and frequency of piezoelectric NEMS via modified multi-physical couple stress theory", Mech. Syst. Signal Pr., 165, 108373. https://doi.org/10.1016/j.ymssp.2021.108373. 
  139. Zare, R., Najaafi, N., Habibi, M., Ebrahimi, F. and Safarpour, H. (2020), "Influence of imperfection on the smart control frequency characteristics of a cylindrical sensor-actuator GPLRC cylindrical shell using a proportional-derivative smart controller", Smart Struct. Syst., 26(4), 469-480. https://doi.org/10.12989/sss.2020.26.4.469 
  140. Zarrinpar, A., Lee, D.K., Silva, A., Datta, N., Kee, T., Eriksen, C., Weigle, K., Agopian, V., Kaldas, F., Farmer, D., Wang, S.E., Busuttil, R., Ho, C.M. and Ho, D. (2016), "Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform", Sci. Transl. Med., 8(333), 333ra349. https:/doi.org/10.1126/scitranslmed.aac5954 
  141. Zhang, Y., Wang, Z., Tazeddinova, D., Ebrahimi, F., Habibi, M. and Safarpour, H. (2021), "Enhancing active vibration control performances in a smart rotary sandwich thick nanostructure conveying viscous fluid flow by a PD controller", Wave. Random Complex Med., 1-24. https://doi.org/10.1080/17455030.2021.1948627 
  142. Zhao, Y., Moradi, Z., Davoudi, M. and Zhuang, J. (2022), "Bending and stress responses of the hybrid axisymmetric system via state-space method and 3D-elasticity theory", Eng. Comput., 1-23. https://doi.org/10.1007/s00366-020-01242-1 
  143. Zheng, Y., Jin, H., Jiang, C., Moradi, Z., Khadimallah, M.A. and Moayedi, H. (2022), "Analyzing behavior of circular concrete-filled steel tube column using improved fuzzy models", Steel Compos. Struct., 43(5), 625-637. https://doi.org/10.12989/scs.2022.43.5.625 
  144. Zhou, C., Zhao, Y., Zhang, J., Fang, Y. and Habibi, M. (2020), "Vibrational characteristics of multi-phase nanocomposite reinforced circular/annular system", Adv. Nano Res., 9(4), 295-307. https://doi.org/10.12989/anr.2020.9.4.295 
  145. Zhu, L., Ren, H., Habibi, M., Mohammed, K.J. and Khadimallah, M.A. (2022), "Predicting the environmental economic dispatch problem for reducing waste nonrenewable materials via an innovative constraint multi-objective Chimp Optimization Algorithm", J. Clean. Prod., 132697. https://doi.org/10.1016/j.jclepro.2022.132697 
  146. Zou, Q., Xing, P., Wei, L. and Liu, B. (2019), "Gene2vec: gene subsequence embedding for prediction of mammalian N6-methyladenosine sites from mRNA", Rna, 25(2), 205-218. https://doi.org/10.1261/rna.069112.118