Journal of Medicine and Life Science

  • 제20권2호
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  • Pages.60-66
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  • 2023
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  • 1738-1010(pISSN)
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  • 2671-4922(eISSN)
제주대학교 의과학연구소 (Institute for Medical Science)
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Doujet GF 골 시멘트를 사용한 인공 슬관절치환술의 임상적, 방사선적 고찰

Clinical and radiologic study of total knee replacement arthroplasty using Doujet GF bone cement (liquid-powder bone cement containing gentamicin)

  • 최성욱 (제주대학교병원 정형외과) ;
  • 윤성민 (제주대학교병원 정형외과) ;
  • 노조셉 (닥터 존 정형외과의원) ;
  • 손인석 (제주대학교병원 정형외과)
  • Sungwook Choi (Department of Orthopedic Surgery, Jeju National University Hospital) ;
  • Seong-meen Yoon (Department of Orthopedic Surgery, Jeju National University Hospital) ;
  • Joseph Y. Rho (Doctor Zone Orthopaedics Clinic) ;
  • In-seok Son (Department of Orthopedic Surgery, Jeju National University Hospital)
  • 투고 : 2022.12.15
  • 심사 : 2023.03.03
  • 발행 : 2023.06.30
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초록

Gentamicin-loaded bone cement used in total joint arthroplasty is indispensable, as it provides stability by directly binding the surfaces of implants and bones. Depending on multiple factors, including the material of the bone cement used, common complications, such as aseptic loosening, osteolysis, and infection can occur postoperatively. In clinical practice, Doujet bone cement is easy to handle (pre-packed all-in-one system), and has shown low failure rates and non-inferior results compared with similar available products. We conducted a retrospective comparative study to analyze the clinical and radiological results of each bone cement group to establish the safety and usefulness of Doujet bone cement. From July 2020 to July 2022, we enrolled 198 patients in this study after an average follow-up period of 37 months (range, 6-48 months). In 99 patents, Doujet® bone cement (Injecta, Gunpo, Korea) was used for total knee arthroplasty (TKA), while Refobacin® bone cement (Biomet, Warsaw, IN, USA) was used in 99 patients. The average range of motion (ROM) of the knee increased by 2.4° (from 127.0° preoperatively to 129.4° postoperatively) in the Doujet group, and by 0.1° (from 128.7° to 128.8°) in the Refobacin group (P=0.701). The Western Ontario and McMaster Universities (WOMAC) osteoarthritis index scores decreased from 44.1 to 7.8 in the Doujet group, and from 44.2 to 6.3 in the Refobacin group (P=0.162). Complications, such as osteolysis or post-operative wound infection, did not occur in more than two cases in both groups. The WOMAC and ROM of the knee in both groups had no clinical differences. Both Doujet and Refobacin similarly showed low complication rates after TKA.

키워드

과제정보

This work was supported by the 2023 education, research and student guidance grant funded by Jeju National University.

참고문헌

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