Dementia and Neurocognitive Disorders (대한치매학회지)

Korean Dementia Association (대한치매학회)
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Effect of Tablet-based Cognitive Intervention on Cognition in Patients With Mild Cognitive Impairment: A Pilot Study

  • Ji Young Park (Geumcheon Center for Dementia) ;
  • Seon Ae Choi (Geumcheon Center for Dementia) ;
  • Jae Joon Kim (Geumcheon Center for Dementia) ;
  • Yu Jeong Park (Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Chi Kyung Kim (Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Geum Joon Cho (Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Seong-Beom Koh (Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Sung Hoon Kang (Geumcheon Center for Dementia)
  • Received : 2023.07.09
  • Accepted : 2023.09.05
  • Published : 2023.10.31
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Abstract

Background and Purpose: Growing evidence has shown that cognitive interventions can mitigate cognitive decline in patients with mild cognitive impairment (MCI). However, most previous cognitive interventions have been group-based programs. Due to their intrinsic limitations, group-based programs are not widely used in clinical practice. Therefore, we have developed a tablet-based cognitive intervention program. This preliminary study investigated the feasibility and effects of a 12-week structured tablet-based program on cognitive function in patients with MCI. Methods: We performed a single-arm study on 24 patients with MCI. The participants underwent a tablet-based cognitive intervention program 5 times a week over a 12-week period. The primary outcome was changes in cognitive function, measured using the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K). Outcomes were evaluated at baseline, within two weeks of the last program (post-intervention), and at the six-month follow-up session. Results: The completion rate of the tablet-based program was 83.3% in patients with MCI. The program improved cognitive function based on the CERAD-K total score (p=0.026), which was maintained for at least three months (p=0.004). There was also an improvement in the depression scale score (p=0.002), which persisted for three months (p=0.027). Conclusions: Our 12-week structured tablet-based program is feasible for patients with MCI. Furthermore, although further studies with a double-arm design are required, the program appears to be an effective strategy to prevent cognitive decline in patients with MCI.

Keywords

Acknowledgement

This research was supported by the Memorial Foundation for Dr. Duk L. Na funded by the Korean Dementia Association.

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