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A Study on the Physiological Activity of Agastachis herba Extract and Fermented Products as Cosmetic Materials

화장품소재로서 곽향 추출물 및 발효물의 생리활성 연구

  • Jeong-Ro Lee (Department of Pharmaceutical Engineering, Woosuk University ) ;
  • Kap-Hoon Han (Department of Pharmaceutical Engineering, Woosuk University ) ;
  • Tae-Goo O (Department of Pharmaceutical Engineering, Woosuk University) ;
  • Jeong-Ran Kang (Department of Pharmaceutical Engineering, Woosuk University)
  • 이정로 (우석대학교 제약공학과) ;
  • 한갑훈 (우석대학교 제약공학과) ;
  • 오태구 (우석대학교 제약공학과) ;
  • 강정란 (우석대학교 제약공학과)
  • Received : 2023.10.09
  • Accepted : 2023.12.30
  • Published : 2023.12.30

Abstract

Agastachis herba is so similar in use to herbs that it is called Korea Mint in the West. Western herbs are commonly used as ingredients in cosmetics. However, in Korea, Agastachis herba is primarily used as a medicinal herb. This study aims to compare the effectiveness of one cosmetic ingredient with another cosmetic ingredient. Antioxidant, whitening, polyphenol, flavonoid, and antibacterial experiments were conducted on lactobacillus, yeast ferments, essential oils, and floral water using extracts from Agastachis herba. Antioxidants exhibited significant effects in all samples, while essential oils displayed the highest efficacy in terms of whitening, polyphenol content, and antibacterial properties. Flavonoids exhibited the strongest effect in the 70% ethanol extract. The essential oil had the most significant functional impact. However, it was confirmed that the fermented products that underwent yeast fermentation with extracts were as effective as essential oils.

곽향은 서양에서 Korea mint라고 불릴 정도로 허브와 쓰임새가 매우 유사하다. 서양의 허브는 화장품의 소재로 많이 사용하지만 곽향은 우리나라에서 약재로 더 많이 사용되어 화장품 소재로서의 기능성을 비교해보았다. 곽향 추출물과 추출물을 이용한 유산균과 효모 발효물, 에센셜오일, 플로럴워터에 대한 항산화, 미백, 폴리페놀, 플라보노이드, 항균력 실험을 진행하였다. 항산화 활성은 모든 샘플에서 높은 효과가 보였고, 미백과 폴리페놀, 항균력에서 에센셜오일이 가장 높은 효과가 보였다. 반면에 플라보노이드는 70% 에탄올 추출물에서 가장 높은 효과가 보였다. 이런 결과로 에센셜오일이 기능적으로 가장 큰 효과가 있었다. 하지만 추출물을 가지고 효모 발효를 진행한 시료들이 에센셜오일 만큼의 효과가 있다는 것을 확인해 에센셜오일의 적은 추출량에 비해 효모 발효를 진행한 시료가 화장품소재로서 충분한 가치가 있다고 본다.

Keywords

Acknowledgement

본 과제(결과물)는 교육부와 한국연구재단의 재원으로 지원을 받아 수행된 3단계 산학연협력 선도대학 육성사업(LINC3.0)의 연구결과의 일부입니다.

References

  1. H. S. Jo, S. M. Hong "Enhancement of the Antibacterial and Antioxidative Capacities of Glehnia littoralis Extracts through Lactic Acid Bacteria Fermentatio", Journal of the Korea Academia-Industrial cooperation Society, Vol.24, No.2, pp. 83-91, (2023). 
  2. J. W. Kim, J. H. Hong "Antioxidant Activity, Skin Whitening, and Anti-Wrinkle Effects of Various Agastache rugosa Fractions", J Korean Soc Food Sci Nutr, Vol.50, No.7 pp. 679-691, (2021). 
  3. J. R. Kang, D. S. Oh, J. H. Kim, K. H. Han, X. X. Huang "A Study of Physiological Activities for Cosmeceutical Ingredient from Fermented Aroniamelanocarpa Extract", Journal of Convergence for Information Technology, Vol.10, No.1, pp. 243-250, (2020). 
  4. S. S. Kim, H. C. Cha "Comparison of the Total Phenolic and Flavonoid Contents and Antioxidant Activities of Four Kinds of Sand Dune Plants Living in Taean", Korea, Korean J. Plant Res, Vol.30, No.1, pp. 8-16. (2017). 
  5. N. I. Kim, S. H. Yang, J. H. Shin, M. H. Choi D. S. Oh "Evaluation of Bioactivity of Castanopsis cuspidata var. sieboldii Leaves Extract and Isolation of Polyphenolic Compounds", Korean Society for Biotechnology and Bioengineering Journal, Vol.37, No.2, pp. 64-70, (2022). 
  6. K. H. Han, J. R. Kang, D. S. Oh, J. H. Kim "Fermented Aroniamelanocarpa Extract manufacturing method and cosmetic composition using it", 10-2017-0183784, Korea, (2017). 
  7. M. W. Han, C. K. Park, C. S. Park, H. J. Ahn, J. B. Seo, Y. J. Lee "Studies on Quality Control of Domestic Agastachis Herba", Kor. J. Herbol, Vol.34, No.2, pp. 67-74, (2019). 
  8. N. Y. Kim, H. J. Kim, J. H. Lee, E. K. Lee, O. H. Kang, D. Y. Kwon, H. S. So, K. N. Lee, M. S. Chong "Comparison of the Anti-inflammatory Effects of Water Fermented and Ethanol Fermented Extracts from Rhei Radix et Rhizoma", Korean J. Oriental Physiology & Pathology, Vol.25, No.2, pp. 227-233, (2011). 
  9. E. S. Seong, S. K. Kim, J. W. Lee, S. H. Choi, J. H. Yoo, J. D. Lim, J. K. Na, C. Y. Yu "Antioxidant and Antibacterial Activities of the Byproducts of Abies holophylla Extract", Korean J. Medicinal Crop Sci., Vol.26, No.2, pp. 134-140, (2018). 
  10. Y. J Park "Antibacterial and Active ingredients of Lithospermum erythrorhizon, Agastache rugosa and Cinnamomum cassia complex extracts", Doctoral dissertation, Semyung University, Jecheon, (2022). 
  11. H. J. Heo, H. R. Shin, J. W. Chung, J. S. Lee "Comparison of Antioxidant Activities in Agastache Species", J Korean Soc Food Sci Nutr, Vol.51, No.4, pp. 389-394, (2022). 
  12. H. M. Son "Study of Anti-inflammatory Activity of Fermented Agastache rugosa Extracts Using Lactic acid Bacteria", Masteral dissertation, Kyunghee University, Seoul, (2014). 
  13. H. K. Kim, Y. A. Kim, J. M. Chun, B. S. Ko "Pattern analysis of Agastachis Herba and Pogostemonis Herba", Kor. J. Pharmacogn., Vol.34, No.4, pp. 274-277, (2003). 
  14. J. H. Kim "Effects of Korean Fragrant Plant Agastache rugosa (Fisch. & C.A.Mey.) Kuntze on Human Brain Psychophysiology", Doctoral dissertation, Kangwon University, Kangwon, (2021). 
  15. M. J. Hong, J. H. Kim, H. Y. Kim, M. J. Kim, S. M. Kim "Chemical Composition and Biological Activity of Essential Oil of Agastache rugosa (Fisch. & C. A. Mey.) O. Kuntz", Korean J. Medicinal Crop Sci., Vol.28, No.2, 95-110, (2020). 
  16. Y. J. Cho, S. H. Kim, J. Y. Choi, J. B. Lee "Antioxidative and Anti-pollutant Activity of Papaver rhoeas Extract", Journal of Next-generation Convergence Technology Association, Vol.7, No.7, pp. 1106-1115, (2023). 
  17. J. Y. Lee, T. H. Park, S. H. Park, S. A. Yang, K. H. Jhee "The Antimicrobial Activity of Fermented Extracts from Korean Dendropanax morbifera", Journal of Life Science, Vol.29, No.1, 29-36, (2019). 
  18. S. Y. Park, K. Y. Hyun "Effect of Natural Substance Extracts on Hair Growth according to Antioxidant Effect", Journal of Next-generation Convergence Technology Association, Vol.6, No.3, pp. 433-444, (2022). 
  19. Y. S. Kim, S. H. You "A Study on the Evaluation of Cosmetic Stability of Broccoli Extracts", Journal of the Korean Applied Science and Technology, Vol. 40, No.5, 1065-1071, (2023). 
  20. H. G. Lee, J. G. Ji "Evaluation of Anti-inflammatory and Antioxidant Abilities of Complex Extracts Produced from Leonurus japonicus Houtt., Houttuynia cordata Thunberg, and Citrus unshiu Markovich", Journal of the Korean Applied Science and Technology, Vol. 40, No. 1, 35-47, (2023). 
  21. S. Y. Kim, M. H. Lee, S. N. Park "Evaluations of Antioxidative Activity and Whitening Effect of Extracts from Different Parts of Cosmos bipinnatus", J. of the Korean Oil Chemists' Soc., Vol. 27, No. 4, 559-567, (2010).