과제정보
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government(MSIT) (No. NRF-2020R1F1A1072032).
참고문헌
- Leong S, Cohen RB, Gustafson DL, Langer CJ, Camidge DR, Padavic K, Gore L, Smith M, Chow LQ, von Mehren M, O'Bryant C, Hariharan S, Diab S, Fox NL, Miceli R, Eckhardt SG (2009) Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study. J Clin Oncol 27: 4413-4421. doi:10.1200/JCO.2008.21.7422
- Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK (2001) Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer. Oncogene 20: 6073-6083. doi: 10.1038/sj.onc.1204736
- Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T, Smith C, Smolak P, Goodwin RG, Rauch CT, Schuh JC, Lynch DH (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nature Medicine 5: 157-163. doi: 10.1038/5517
- Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A (2000) Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12: 611-620. doi: 10.1016/S1074-7613(00)80212-5
- Ashkenazi A, Dixit VM (1998) Death receptors: signaling and modulation. Science 281: 1305-1308. doi: 10.1126/science.281.5381.13
- Yamanaka T, Shiraki K, Sugimoto K, Ito T, Fujikawa K, Ito M, Takase K, Moriyama M, Nakano T, Suzuki A (2000) Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 32(3): 482-490. doi: 10.1053/jhep.2000.16266
- Pedraza-Chaverri J, Cardenas-Rodriguez N, Orozco-Ibarra M (2008) Medicinal properties of mangosteen (Garcinia mangostana). Food Chem Toxicol 46: 3227-3239. doi: 10.1016/j.fct.2008.07.024
- Suksamrarn S, Komutiban O, Ratananukul P, Chimnoi N, Lartpornmatulee N, Suksamrarn (2006) Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana. Chem Pharm Bull 54: 301-305. doi:10.1248/cpb.54.301
- Jung HA, Su BN, Keller WJ, Mehta RG, Kinghorn AD (2006) Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen). J Agric Food Chem 54: 2077-2082. doi: 10.1021/jf052649z
- Luo M, Liu Q, He M, Yu Z, Pi R, Li M, Yang X, Wang S, Liu A (2017) Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells. J Cell Mol Med 21: 46-57. doi: 10.1111/jcmm.12937
- Pham V, Rendon R, Le VX, Tippin M, Fu DJ, Le TH, Miller M, Agredano E, Cedano J, Zi X (2020) Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagy. Mol Carcinog 259(2): 193-201. doi: 10.1002/mc.23140
- Kim BR, Park SH, Jeong YA, Na YJ, Kim JL, Jo MJ, Jeong S, Yun HK, Oh SC, Lee D-H (2009) RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer. Oncogene 38: 3903-3918. doi:10.1038/s41388-019-0693-x
- van Geelen CM, Pennarun B, Le PT, de Vries EG, de Jong S (2011) Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5. BMC Cancer 27: 11-39. doi: 10.1186/1471-2407-11-39
- Yamaguchi H, Wang HG (2004) CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. J Biol Chem 279: 45495-45502. doi: 10.1074/jbc.M406933200
- Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T (2005) Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein. Cancer Research 65: 5662-5667. doi: 10.1158/0008-5472.CAN-05-0693
- Okada T, Yoshida H, Akazawa R, Negishi M, Mori K (2002) Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response. Biochem J 366: 585-594. doi: 10.1042/bj20020391
- Szegezdi E, Logue SE, Gorman AM, Samali A (2006) Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7: 880-885. doi: 10.1038/sj.embor.7400779
- Malhotra JD, Kaufman RJ (2007) The endoplasmic reticulum and the unfolded protein response. Semin Cell Dev Biol 18: 716-731. doi:10.1016/j.semcdb.2007.09.003
- Gupta SC, Hevia D, Patchva S, Park B, Koh W, Aggarwal BB (2012) Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy. Antioxidants and Redox Signaling 16(11): 1295-1322. doi: 10.1089/ars.2011.4414
- Sciarretta S, Zhai P, Shao D, Zablocki D, Nagarajan N, S. Terada L, Volpe M, Sadoshima J (2013) Activation of NADPH oxidase 4 in the endoplasmic reticulum promotes cardiomyocyte autophagy and survival during energy stress through the protein kinase RNA-activated-like endoplasmic reticulum kinase/eukaryotic initiation factor 2α/activating transcription factor 4 pathway. Circulation Research 113: 1253-1264. doi: 10.1161/CIRCRESAHA.113.301787
- Kroemer G, Marino G, Levine B (2010) Autophagy and the integrated stress response. Mol cell 40: 280-293. doi: 10.1016/j.molcel.2010.09.023
- Meng T, Lin S, Zhuang H, Huang H, He Z, Hu Y, Gong Q, Feng D (2019) Recent progress in the role of autophagy in neurological diseases. Cell Stress 29: 141-161. doi: 10.15698/cst2019.05.186
- Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. The EMBO Journal 19: 5720-5728. doi: 10.1093/emboj/19.21.5720
- Seibenhener ML, Babu JR, Geetha T, Wong HC, Krishna NR, Wooten MW (2004) Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol Cell Biol 24(18):8055-8068. doi: 10.1128/MCB.24.18.8055-8068.2004
- Mora R, Abschuetz A, Kees T, Dokic I, Joschko N, Kleber S, Geibig R, Mosconi E, Zentgraf H, Martin-Villalba A, Regnier-Vigouroux A (2009) TNF-alpha- and TRAIL-resistant glioma cells undergo autophagy-dependent cell death induced by activated microglia. Glia 57: 561-581. doi: 10.1002/glia.20785
- Herrero-Martin G, Hoyer-Hansen M, Garcia-Garcia C, Fumarola C, Farkas T, Lopez-Rivas A, Jaattela M (2009) TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells. The EMBO journal 28: 677-685. doi: 10.1038/emboj.2009.8
- Nazim UM, Moon JH, Lee JH, Lee YJ, Seol JW, Eo SK, Lee JH, Park SY (2016) Activation of autophagy flux by metformin downregulates cellular FLICE-like inhibitory protein and enhances TRAIL-induced apoptosis. Oncotarget 26: 23468-23481. doi: 10.18632/oncotarget.8048
- Chen L, Meng Y, Sun Q, Zhang Z, Guo X, Sheng X, Tai G, Cheng H, Zhou Y (2016) Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and - independent DR5 upregulation. Cell Death Dis 11: 1-222. doi: 10.1038/cddis.2016.234
- Prasad S, Kim JH, Gupta SC, Aggarwal BB (2014) Targeting death receptors for TRAIL by agents designed by Mother Nature. Trends Pharmacol Sci 35: 520-536. doi: 10.1016/j.tips.2014.07.004
- Sung B, Park B, Yadav VR, Aggarwal BB (2010) Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors. J Biol Chem 285: 16920. doi: 10.1074/jbc.M109.090209
- Hayashi T, Saito A, Okuno S, Ferrand-Drake M, Dodd RL, Nishi T, Maier CM, Kinouchi H, Chan PH (2003) Oxidative damage to the endoplasmic reticulum is implicated in ischemic neuronal cell death. J Cereb Blood Flow Metab 23: 1117-1128 https://doi.org/10.1097/01.WCB.0000089600.87125.AD