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A Rare Case of Intestinal T-cell Lymphoma with Multiple Complications

  • Seung Yong Shin (Department of Internal Medicine, Chung-Ang University College of Medicine)
  • Received : 2023.07.26
  • Accepted : 2023.08.07
  • Published : 2023.08.20

Abstract

Intestinal T-cell lymphoma is a rare and aggressive form of non-Hodgkin lymphoma. Owing to its rarity and variable manifestations, intestinal T-cell lymphoma is usually diagnosed at an advanced stage. Therefore, it may be accompanied with serious complications at the time of diagnosis. Herein, I reports a case of intestinal T-cell lymphoma with multiple severe complications.

Keywords

Acknowledgement

Heon-Kyun Ha, M.D. (Surgeon) and Soo Kee Min, M.D. (Pathologist) contributed to this report.

References

  1. Radaszkiewicz T, Dragosics B, Bauer P. Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosis. Gastroenterology 1992;102:1628-1638. https://doi.org/10.1016/0016-5085(92)91723-h
  2. Shirwaikar Thomas A, Schwartz M, Quigley E. Gastrointestinal lymphoma: the new mimic. BMJ Open Gastroenterol 2019;6:e000320. https://doi.org/10.1136/bmjgast2019-000320
  3. Kohno S, Ohshima K, Yoneda S, Kodama T, Shirakusa T, Kikuchi M. Clinicopathological analysis of 143 primary malignant lymphomas in the small and large intestines based on the new WHO classification. Histopathology 2003;43:135-143. https://doi.org/10.1046/j.1365-2559.2003.01659.x
  4. Kim SJ, Choi CW, Mun YC, et al. Multicenter retrospective analysis of 581 patients with primary intestinal nonhodgkin lymphoma from the Consortium for Improving Survival of Lymphoma (CISL). BMC Cancer 2011;11:321. https://doi.org/10.1186/1471-2407-11-321
  5. Chun HB, Baek IH, Lee MS, et al. Jejunocolic fistula associated with an intestinal T cell lymphoma. Gut Liver 2011;5:387-390. https://doi.org/10.5009/gnl.2011.5.3.387
  6. Sun ZH, Zhou HM, Song GX, Zhou ZX, Bai L. Intestinal T-cell lymphomas: a retrospective analysis of 68 cases in China. World J Gastroenterol 2014;20:296-302. https://doi.org/10.3748/wjg.v20.i1.296
  7. Nishimura MF, Nishimura Y, Nishikori A, Yoshino T, Sato Y. Primary gastrointestinal T-cell lymphoma and indolent lymphoproliferative disorders: practical diagnostic and treatment approaches. Cancers (Basel) 2021;13:5774. https://doi.org/10.3390/cancers13225774
  8. Bautista-Quach MA, Ake CD, Chen M, Wang J. Gastrointestinal lymphomas: morphology, immunophenotype and molecular features. J Gastrointest Oncol 2012;3:209-225. https://doi.org/10.3978/j.issn.2078-6891.2012.024
  9. Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016;127:2375-2390. https://doi.org/10.1182/blood-2016-01-643569
  10. Chan JK, Chan AC, Cheuk W, et al. Type II enteropathy-associated T-cell lymphoma: a distinct aggressive lymphoma with frequent γδ T-cell receptor expression. Am J Surg Pathol 2011;35:1557-1569. https://doi.org/10.1097/PAS.0b013e318222dfcd
  11. Tse E, Gill H, Loong F, et al. Type II enteropathy-associated T-cell lymphoma: a multicenter analysis from the Asia Lymphoma Study Group. Am J Hematol 2012;87:663-668. https://doi.org/10.1002/ajh.23213
  12. Tan SY, Chuang SS, Tang T, et al. Type II EATL (epithetliotropic intestinal T-cell lymphoma): a neoplasm of intraepithelial T-cells with predominant CD8αα phenotype. Leukemia 2013;27:1688-1696. https://doi.org/10.1038/leu.2013.41
  13. Daum S, Ullrich R, Heise W, et al. Intestinal non-Hodgkin's lymphoma: a multicenter prospective clinical study from the German Study Group on Intestinal non-Hodgkin's Lymphoma. J Clin Oncol 2003;21:2740-2746. https://doi.org/10.1200/JCO.2003.06.026
  14. Malamut G, Chandesris O, Verkarre V, et al. Enteropathy associated T cell lymphoma in celiac disease: a large retrospective study. Dig Liver Dis 2013;45:377-384. https://doi.org/10.1016/j.dld.2012.12.001
  15. Cellier C, Delabesse E, Helmer C, et al. Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. French Coeliac Disease Study Group. Lancet 2000;356:203-208. https://doi.org/10.1016/s0140-6736(00)02481-8
  16. Yi JH, Lee GW, Do YR, et al. Multicenter retrospective analysis of the clinicopathologic features of monomorphic epitheliotropic intestinal T-cell lymphoma. Ann Hematol 2019;98:2541-2550. https://doi.org/10.1007/s00277-019-03791-y
  17. Novakovic BJ, Novakovic S, Frkovic-Grazio S. A singlecenter report on clinical features and treatment response in patients with intestinal T cell non-Hodgkin's lymphomas. Oncol Rep 2006;16:191-195. https://doi.org/10.3892/or.16.1.191
  18. Nijeboer P, Malamut G, Mulder CJ, et al. Enteropathy-associated T-cell lymphoma: improving treatment strategies. Dig Dis 2015;33:231-235. https://doi.org/10.1159/000369542
  19. Gale J, Simmonds PD, Mead GM, Sweetenham JW, Wright DH. Enteropathy-type intestinal T-cell lymphoma: clinical features and treatment of 31 patients in a single center. J Clin Oncol 2000;18:795-803. https://doi.org/10.1200/JCO.2000.18.4.795
  20. Egan LJ, Walsh SV, Stevens FM, Connolly CE, Egan EL, McCarthy CF. Celiac-associated lymphoma. A single institution experience of 30 cases in the combination chemotherapy era. J Clin Gastroenterol 1995;21:123-129. https://doi.org/10.1097/00004836-199509000-00012