The Journal of Korean Society for School & Community Health Education (한국학교ㆍ지역보건교육학회지)

The Korean Society for School & Community Health Education (한국학교ㆍ지역보건교육학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Handgrip Strength to Cognitive Impairment in Patients with Hypertension

고혈압 환자의 악력수준이 인지기능 저하에 미치는 영향

  • Eun-Jung Bae (Department of Nursing, Catholic University of Pusan) ;
  • Il-Su Park (Department of Healthcare Management, Dong-eui University)
  • 배은정 (부산가톨릭대학교 간호학과) ;
  • 박일수 (동의대학교 의료경영학과)
  • Received : 2023.11.01
  • Accepted : 2023.11.14
  • Published : 2023.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to investigate the effect of handgrip strength level on cognitive impairment in hypertensive patients. Methods: This study used the first to eighth year data of the Korean Longitudinal Study of Aging (KLoSA). Of the 10,254 respondents who participated in the basic survey, respondents were included that they were diagnosed with high blood pressure and had no cognitive impairment. The handgrip strength was based on the highest value of handgrip strength for both hands. Cognitive function using MMSE results and 23 points or less were defined as cognitive impairment. Cox models were conducted to estimate the hazard ratios (HRs) of cognitive impairment in relation to handgrip strength adjusting for covariates. Results: In the case of hypertension patients, the probability of cognitive decline decreased by 3.0% every time the maximum handgrip strength increased by 1 unit. In the analysis by age, under the age of 64 had a 1.8% decrease in the probability of cognitive decline whenever the maximum handgrip strength increased by 1 unit, and a 3.6% decrease in those over the age of 65. In the gender analysis, male had a 3.2% decrease in the probability of cognitive decline for every 1 unit increase in the maximum handgrip strength, and female had a 2.6% decrease. Conclusions: The results of this study are expected to be used as basic data for the development of interventions to prevent cognitive decline in hypertensive patients by identifying the effect of handgrip strength level on cognitive decline. It is also expected to be used as basic data for health education on the necessity of increasing muscle strength for hypertension patients in the community.

Keywords

Acknowledgement

이 논문은 2021년도 부산가톨릭대학교 교내연구비에 의하여 연구되었음

References

  1. 고진경, 조문기. (2018). 치매조기검진제도에 대한 한.일 비교연구. 일본문화연구, 67(1), 331-344.
  2. 김경, 권대규, 홍철운, 김남균. (2004). 의식적인 손 운동을 통한 뇌기능 증진의 메커니즘에 관한 연구. 공학연구, 35(1), 103-107.
  3. 신현구, 부가청, 이혜정. (2006). 고령화연구패널조사 제 1차 기본조사 소개. 노동리뷰, 21, 90-99.
  4. 이성은. (2014). 노인의 악력과 인지기능의 관계. 한국지역사회생활과학회지, 25(1), 29-37.
  5. 장성호, 박승규, 김재원, 김오룡, 양동석, 권용현 (2006). 호두를 이용한 손 운동이 대뇌 피질의 활성화에 미치는 영향. 대한작업치료학회지. 14(1). 25-33.
  6. 중앙치매센터 (2023). 대한민국 치매현황 2022 [Internet]. Retrived from https://www.nid.or.kr/info/dataroom_view.aspx?bid=257
  7. 최명진, 김기연. (2019). 노인의 상대적 악력이 인지기능에 미치는 영향: 경제활동과 사회참여의 조절효과를 중심으로. 한국노년학회지, 39(3), 549-567.
  8. 통계청. (2023). 2023 고령자 통계. 서울: 통계청.
  9. Barha CK, Davis JC, Falck RS, Nagamatsu LS, Liu-Ambrose T. (2017). Sex differences in exercise efficacy to improve cognition: A systematic review and meta-analysis of randomized controlled trials in older humans. Front. Neuroendocrinol, 46, 71-85. https://doi.org/10.1016/j.yfrne.2017.04.002
  10. de la Torre JC (2000). Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer's pathogenesis. Neurobiology of aging, 21(2), 331-342. https://doi.org/10.1016/S0197-4580(00)00111-1
  11. Folstein MF, Folstein SE, McHugh PR. (1975). "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189-198. https://doi.org/10.1016/0022-3956(75)90026-6
  12. Fritz NE, McCarthy CJ, Adamo DE. (2017). Handgrip strength as a means of monitoring progression of cognitive decline-A scoping review. Ageing Research Reviews, 35(1), 112-123. https://doi.org/10.1016/j.arr.2017.01.004
  13. Hou Y, Dan X, Babbar M, Wei Y, Hasselbalch SG, Croteau, DL, et al. (2019). Ageing as a risk factor for neurodegenerative disease. Nature Reviews Neurology, 15(10), 565-581. https://doi.org/10.1038/s41582-019-0244-7
  14. Kalaria RN (2000). The role of cerebra ischemia in Alzheimer's disease. Neurobiology of aging, 21(2), 321-330. https://doi.org/10.1016/S0197-4580(00)00125-1
  15. Kang YW, Na DL, Hahn SH. (1997). A validity study on the Korean Mini-Mental State Examination (K-MMSE) in dementia patients. Journal of the Korean Neurological Association, 15(2), 300-308.
  16. Lawman HG, Troiano RP, Perna FM, Wang CY, Fryar CD, Ogden CL. (2016). Associations of relative handgrip strength and cardiovascular disease biomarkers in US adults, 2011-2012. American Journal of Preventive Medicine, 50(6), 677-683.
  17. Lee HJ, Kahng SK. (2011). The reciprocal relationship between cognitive functioning and depressive symptom: Group comparison by gender. Korean Journal of Social Welfare Studies, 42(2), 179-203.
  18. Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee, S, et al. (2020). Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. The Lancet, 396(10248), 413-446. https://doi.org/10.1016/S0140-6736(20)30367-6
  19. Lu S, Herold F, Zhang Y, Lei Y, Kramer AF, Jiao C, Yu Q, et al. (2021). Higher Handgrip Strength Is Linked to Better Cognitive Performance in Chinese Adults with Hypertension. Brain Sciences, 11(8), 985.
  20. Meskers CM, Reijnierse EM, Numans ST, Kruizinga RC, Pierik VD, van Ancum JM, et al. (2019). Association of handgrip strength and muscle mass with dependency in(instrumental) activities of daily living in hospitalized ilder adults-the EMPOWER Study. The Journal of Nutrition, Health & Aging, 23(3), 232-238. https://doi.org/10.1007/s12603-019-1170-5
  21. Petrovitch H, White LR, Izmirilian G, Ross GW, Havlik RJ, Markesbery W, et al. (2000). Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death; the HAAS. Neurobiology of aging, 21(1), 57-62. https://doi.org/10.1016/S0197-4580(00)00106-8
  22. Nishiguchi S, Yamada M, Fukutani N, et al. (2015). Differential association of frailty with cognitive decline and sarcopenia in community-dwelling older adults. Journal of the American Medical Directors Association, 16(2), 120-124. https://doi.org/10.1016/j.jamda.2014.07.010
  23. Rabensteiner J, Hofer E, Fauler G, Fritz-Petrin E, Benke T, Dal-Bianco P, et al. (2020). The impact of folate and vitamin B12 status on cognitive function and brain atrophy in healthy elderly and demented Austrians, a retrospective cohort study. Aging(Alban NY), 12(15), 15478-15491. https://doi.org/10.18632/aging.103714
  24. Taekema DG, Gussekloo J, Maier AB, Westendorp RG, de Craen AJ (2010). Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old. Age Ageing, 39(3), 331-337. https://doi.org/10.1093/ageing/afq022
  25. Weaver JD, Huang MH, Albert M, Harris T, Rowe JW, & Seeman TE. (2002). Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology, 59(3), 371-378. https://doi.org/10.1212/WNL.59.3.371