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Effect of Water on Lecithin/Bile/Decane Organogels

레시틴/담즙염/데케인 유기젤에 대한 물의 영향

  • Eun-ae Chu (Department of Chemical Engineering, Kumoh National Institute of Technology) ;
  • Na-hyeon Kim (Department of Chemical Engineering, Kumoh National Institute of Technology) ;
  • Min-seok Kang (Department of Chemical Engineering, Kumoh National Institute of Technology) ;
  • Kyo-chan Koo (Department of Management Engineering, Dankook University) ;
  • Hee-Young Lee (Department of Chemical Engineering, Kumoh National Institute of Technology)
  • 추은애 (금오공과대학교 화학공학과) ;
  • 김나현 (금오공과대학교 화학공학과) ;
  • 강민석 (금오공과대학교 화학공학과) ;
  • 구교찬 (단국대학교 경영공학과) ;
  • 이희영 (금오공과대학교 화학공학과)
  • Received : 2023.11.14
  • Accepted : 2023.11.30
  • Published : 2023.12.31

Abstract

Lecithin self-assembles into reverse spherical micelles in organic solvents as an amphiphilic molecule. When additives such as bile salts and water are introduced into lecithin solutions, it induces structural changes in the molecular form of lecithin, leading to the transformation into reverse cylindrical micelles. In this study, we observe the rheological changes of lecithin/bile salt mixtures in a decane system after the addition of water. The resulting mixtures exhibit high viscosity and characteristics of viscoelasticity, suggesting potential applications in various fields such as drug delivery and edible oil gels.

레시틴은 양친매성 분자로 유기용매상에서 구형의 역 마이셀로 자가조립된다. 이러한 레시틴 용액에 담즙염, 물 등과 같은 첨가제가 들어갈 경우 레시틴의 분자 형태의 구조 변화를 유도하여 역 실린더형 마이셀로의 변환을 이끈다. 이번 연구에서는, 데케인 상에서 레시틴/담즙염 혼합물에 물을 첨가한 후, 유동계를 활용하여 혼합물의 유변학적 변화를 관찰한다. 이렇게 제조된 혼합물들은 점도가 높고 점탄성의 특징을 나타내어 약물전달, 식품젤 등의 다양한 분야에 활용이 가능할 것으로 기대된다.

Keywords

Acknowledgement

이 연구는 금오공과대학교 학술연구비로 지원되었음 (202103770001).

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