Childhood Kidney Diseases

Korean Society of Pediatric Nephrology (대한소아신장학회)
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BK polyomavirus-associated nephropathy

  • Ahn, Yo Han (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kang, Hee Gyung (Department of Pediatrics, Seoul National University College of Medicine)
  • Received : 2022.04.05
  • Accepted : 2022.05.04
  • Published : 2022.06.30
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Abstract

BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft recipients or hemorrhagic cystitis of hematopoietic stem cell transplant recipients. Currently, there is no effective treatment for BKVAN; therefore, careful monitoring and prudent modification of immunosuppression are necessary to prevent BKVAN. In this article, the epidemiology, pathophysiology, and current management strategies for BKVAN are reviewed.

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References

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