Acknowledgement
This manuscript is not the part of any thesis of any doctoral student but the arduous efforts of Gowhar Rashid and Dr. Rafia Rasool.The authors are highly thankful to the Dr. Tajamul Salim, Senior Resident Department of General Medicine, SKIMS for his support in circulation of questionnaire among the doctors of various specialities. The authors receive no financial support for the research, authorship, and/or publication of this article.
References
- GHE. TB in India - Elimination, National Plans, COVID [Internet]. UK: GHE; 2022 [cited 2022 January 16]. Available from: https://tbfacts.org/tb-india
- The times of India. Lakshadweep, district Budgam in JK declared TB free. [Internet] Bennett, Coleman & Co. Ltd; 2021 [cited 2021 December 1]. Available from: http://timesofindia.indiatimes.com
- Subinay D, Mrinal P. Adenosine deaminase and its isoenzyme as a diagnostic marker in tubercular pleural effusion. J Drug Del Ther. 2014;4:18-21. https://doi.org/10.22270/jddt.v4i1.730
- Shadia K, Kamal SMM, Saleh AA, Hossain MN, Gupta RD, Miah MRA. Adenosine deaminase assay in different body fluids for the diagnosis of tubercular infection. Am J Biomed Sci. 2015;3:49-54. http://doi.org/10.11648/j.ajbls.20150303.14
- Koff A, Azar MM. Diagnosing peritoneal tuberculosis. BMJ Case Rep. 2020;13:e233131. http://doi.org/10.1136/bcr-2019-233131
- Flinn AM, Gennery AR. Adenosine deaminase deficiency: a review. Orphanet J Rare Dis. 2018;13:65. http://doi.org/10.1186/s13023-018-0807-5
- Moens L, Hershfield M, Arts K, Aksentijevich I, Meyts I. Human adenosine deaminase 2 deficiency: a multi-faceted inborn error of immunity. Immunol Rev. 2019;287:62-72. http://doi.org/10.1111/imr.12722
- Kaya S, Cetin ES, Aridogan BC, Arikan S, Demirci M. Adenosine deaminase activity in serum of patients with hepatitis-a useful tool in monitoring clinical status. J Microbiol Immunol Infect. 2007;40:288-292.
- Moreno E, Canet J, Gracia E, Lluis C, Mallol J, Canela EI, et al. Molecular evidence of adenosine deaminase linking adenosine A2A receptor and CD26 proteins. Front Pharmacol. 2018;9:106. http://doi.org/10.3389/fphar.2018.00106
- Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of adenosine receptors: the state of the art. Physiol Rev. 2018;98: 1591-1625. http://doi.org/10.1152/physrev.00049.201
- Hasko G, Antonioli L, Cronstein BN. Adenosine metabolism, immunity and joint health. Biochem Pharmacol. 2018; 151:307-313. http://doi.org/10.1016/j.bcp.2018.02.002
- Barua R, Hossain MA. Adenosine deaminase in diagnosis of tuberculosis: a review. AKMMC J. 2014;5:43-48. https://doi.org/10.3329/akmmcj.v5i2.21132
- Tiruviluamala P, Reichman LB. Tuberculosis. Annu Rev Public Health. 2002;23:403-26. http://doi.org/10.1146/annurev.publhealth.23.100901.140519
- Mishra OP, Yusaf S, Ali Z, Nath G, Das BK. Adenosine deaminase activity and lysozyme levels in children with tuberculosis. J Trop Pediatr. 2000;46:175-178. http://doi.org/10.1093/tropej/46.3.175
- Golden MP, Vikram HR. Extrapulmonary tuberculosis: an overview. Am Fam Physician. 2005;72:1761-1768.
- Krenke R, Korczynski P. Use of pleural fluid levels of adenosine deaminase and interferon gamma in the diagnosis of tuberculous pleuritis. Curr Opin Pulm Med. 2010;16:367-375. http://doi.org/10.1097/MCP.0b013e32833a7154
- Flinn AM, Gennery AR. Adenosine deaminase deficiency: a review. Orphanet J Rare Dis. 2018;13:65. http://doi.org/10.1186/s13023-018-0807-5
- Giblett ER, Anderson JE, Cohen F, Pollara B, Meuwissen HJ. Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. Lancet. 1972;2:1067-1069. http://doi.org/10.1016/s0140-6736 (72)92345-8
- Burgess LJ, Maritz FJ, Le Roux I, Taljaard JJ. Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy. Thorax. 1995;50:672-674. http://doi.org/10.1136/thx.50.6.672
- Jimenez Castro D, Diaz Nuevo G, Perez-Rodriguez E, Light RW. Diagnostic value of adenosine deaminase in nontuberculous lymphocytic pleural effusions. Eur Respir J. 2003;21:220-224. http://doi.org/10.1183/09031936.03.00051603
- Gupta BK, Bharat V, Bandyopadhyay D. Sensitivity, specificity, negative and positive predictive values of adenosine deaminase in patients of tubercular and non-tubercular serosal effusion in India. J Clin Med Res. 2010;2:121-126. http://doi.org/10.4021/jocmr2010.05.289w
- Salmanzadeh S, Tavakkol H, Bavieh K, Alavi SM. Diagnostic value of serum adenosine deaminase (ADA) level for pulmonary tuberculosis. Jundishapur J Microbio. 2015;8:e21760. http://doi.org/10.5812/jjm.21760
- Forouhi NG, Sattar N. CVD risk factors and ethnicity-a homogeneous relationship? Atheroscler Suppl. 2006;7:11-19. http://doi.org/10.1016/j.atherosclerosissup.2006.01.003
- Corbo RM, Scacchi R, Cossu G, Brega A, Scozzari R. Genetic studies on the Senegal population. II. Polymorphisms of the plasma proteins F13A, F13B, ORM1, AHSG, C6, C7, and APOC2. Hum Biol. 1994;66:885-903.
- Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016;16:626-638. http://doi.org/10.1038/nri.2016.90
- Fischer J, Jung N, Robinson N, Lehmann C. Sex differences in immune responses to infectious diseases. Infection. 2015;43:399-403. http://doi.org/10.1007/s15010-015-0791-9
- Gebhard C, Regitz-Zagrosek V, Neuhauser HK, Morgan R, Klein SL. Impact of sex and gender on COVID-19 outcomes in Europe. Biol Sex Differ. 2020;11:29. http://doi.org/10.1186/s13293-020-00304-9
- Eshima N, Tokumaru O, Hara S, Bacal K, Korematsu S, Karukaya S, et al. Age-specific sex-related differences in infections: a statistical analysis of national surveillance data in Japan. PLoS One. 2012;7:e42261. http://doi.org/10.1371/journal.pone.0042261