DOI QR코드

DOI QR Code

다중 심층신경망을 이용한 심전도 파라미터의 획득 및 분류

Acquisition and Classification of ECG Parameters with Multiple Deep Neural Networks

  • 김지운 (강원대학교 문화예술.공과대학 스마트헬스과학기술융합학과) ;
  • 박성민 (강원대학교 의학전문대학원 흉부외과) ;
  • 최성욱 (강원대학교 문화예술.공과대학 스마트헬스과학기술융합학과)
  • Ji Woon, Kim (Interdisciplinary Program in Biohealth-Machinery Convergence Engineering, Kangwon National University) ;
  • Sung Min, Park (Department of Thoracic & Cardiovascular Surgery, School of Medicine, Kangwon National University) ;
  • Seong Wook, Choi (Interdisciplinary Program in Biohealth-Machinery Convergence Engineering, Kangwon National University)
  • 투고 : 2022.11.29
  • 심사 : 2022.12.12
  • 발행 : 2022.12.31

초록

As the proportion of non-contact telemedicine increases and the number of electrocardiogram (ECG) data measured using portable ECG monitors increases, the demand for automatic algorithms that can precisely analyze vast amounts of ECG is increasing. Since the P, QRS, and T waves of the ECG have different shapes depending on the location of electrodes or individual characteristics and often have similar frequency components or amplitudes, it is difficult to distinguish P, QRS and T waves and measure each parameter. In order to measure the widths, intervals and areas of P, QRS, and T waves, a new algorithm that recognizes the start and end points of each wave and automatically measures the time differences and amplitudes between each point is required. In this study, the start and end points of the P, QRS, and T waves were measured using six Deep Neural Networks (DNN) that recognize the start and end points of each wave. Then, by synthesizing the results of all DNNs, 12 parameters for ECG characteristics for each heartbeat were obtained. In the ECG waveform of 10 subjects provided by Physionet, 12 parameters were measured for each of 660 heartbeats, and the 12 parameters measured for each heartbeat well represented the characteristics of the ECG, so it was possible to distinguish them from other subjects' parameters. When the ECG data of 10 subjects were combined into one file and analyzed with the suggested algorithm, 10 types of ECG waveform were observed, and two types of ECG waveform were simultaneously observed in 5 subjects, however, it was not observed that one person had more than two types.

키워드

과제정보

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2020R1F1A1073478). This research was supported by "Regional Innovation Strategy (RIS)" through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (MOE) (2022RIS-005). This work was supported by the Commercializations Promotion Agency for R&D Outcomes (COMPA) grant funded by the Korean Government (Miinistery of Science and ICT) (2022)

참고문헌

  1. Kim H, Yazicioglu RF, Merken P, Van Hoof C, Yoo HJ. ECG signal compression and classification algorithm with quad level vector for ECG holter system. IEEE Transactions on Information Technology in Biomedicine. 2009;14(1):93-100. 
  2. Makikallio TH, Barthel P, Schneider R, Bauer A, Tapanainen JM, Tulppo MP, ..., Huikuri HV. Prediction of sudden cardiac death after acute myocardial infarction: role of Holter monitoring in the modern treatment era. European heart journal. 2005;26(8):762-769.  https://doi.org/10.1093/eurheartj/ehi188
  3. Atarashi H, Ogawa S, Idiopathic Ventricular Fibrillation Investigators. New ECG criteria for high-risk Brugada syndrome. Circulation journal. 2003;67(1):8-10.  https://doi.org/10.1253/circj.67.8
  4. Sathyapriya L, Murali L, Manigandan T. Analysis and detection R-peak detection using Modified Pan-Tompkins algorithm. In 2014 IEEE International Conference on Advanced Communications, Control and Computing Technologies. 2014;483-487. 
  5. ubeyli ED. Recurrent neural networks employing Lyapunov exponents for analysis of ECG signals. Expert systems with applications. 2010;37(2):1192-1199.  https://doi.org/10.1016/j.eswa.2009.06.022
  6. Yildirim O, Plawiak P, Tan RS, Acharya UR. Arrhythmia detection using deep convolutional neural network with long duration ECG signals. Computers in biology and medicine. 2018;102:411-420.  https://doi.org/10.1016/j.compbiomed.2018.09.009
  7. Acharya UR, Fujita H, Oh SL, Hagiwara Y, Tan JH, Adam M. Application of deep convolutional neural network for automated detection of myocardial infarction using ECG signals. Information Sciences. 2017;415:190-198.  https://doi.org/10.1016/j.ins.2017.06.027
  8. Sannino G, De Pietro G. A deep learning approach for ECG-based heartbeat classification for arrhythmia detection. Future Generation Computer Systems. 2018;86:446-455. 
  9. Goto S, Kimura M, Katsumata Y, Goto S, Kamatani T, Ichihara G, ..., Sano M. Artificial intelligence to predict needs for urgent revascularization from 12-leads electrocardiography in emergency patients. PloS one. 2019;14(1):e0210103. 
  10. Reiss A, Schmidt P, Indlekofer I, Laerhoven KV. PPG-based heart rate estimation with time-frequency spectra: A deep learning approach. In Proceedings of the 2018 ACM International Joint Conference and 2018 International Sympo-sium on Pervasive and Ubiquitous Computing and Wearable Computers. 2018;1283-1292. 
  11. Kim JW, Park SM, Choi SW. Automatic parameter acquisition of 12 leads ECG using continuous data processing deep neural network. Journal of Biomedical Engineering Re-search. 2020;41(2):107-119. 
  12. Kim JW, Park SM, Choi SW. Real-time photople-thysmographic heart rate measurement using deep neural network filters. ETRI journal. 2021;43(5):881-890.  https://doi.org/10.4218/etrij.2020-0394
  13. Kim JW, Choi SW. Normalization of photoplethys-mography using deep neural networks for individual and group comparison. Scientific Reports. 2022;12(1):1-10.  https://doi.org/10.1038/s41598-021-99269-x
  14. Goldberger AL, Amaral LA, Glass L, Hausdorff JM, Ivanov PC, Mark RG, ..., Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals. circulation. 2000;101(23):e215-e220. 
  15. Johannesen L, Vicente J, Mason JW, Sanabria C, Waite-Labott K, Hong M, ..., Strauss DG. Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil. Clinical Pharmacology & Therapeutics. 2014;96(5):549-558.  https://doi.org/10.1038/clpt.2014.155
  16. Garcia-Gonzalez MA, Argelagos-Palau A, Fernandez-Chimeno M, Ramos-Castro J. A comparison of heartbeat detectors for the seismocardiogram. In Computing in Cardiology 2013, IEEE. 2013;461-464.