Neonatal Medicine

  • 제28권1호
  • /
  • Pages.41-47
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  • 2021
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  • 2287-9412(pISSN)
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  • 2287-9803(eISSN)
대한신생아학회 (The Korean Society of Neonatology)
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Transient Neonatal Diabetes Mellitus Managed with Continuous Subcutaneous Insulin Infusion (CSII) and Continuous Glucose Monitoring

  • Kim, Min Soo (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Kim, Sung Eun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Na Yeong (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Kim, Seul Ki (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Kim, Shin Hee (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Cho, Won Kyoung (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Cho, Kyoung Soon (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Jung, Min Ho (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Suh, Byung-Kyu (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Ahn, Moon Bae (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
  • 투고 : 2020.09.11
  • 심사 : 2020.10.15
  • 발행 : 2021.02.28
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초록

Neonatal diabetes mellitus can be categorized as transient, permanent, or syndromic, and approximately half of the cases are transient. We present a case involving a term newborn who showed overt progression of transient neonatal diabetes mellitus, with complete remission within 6 months. On the second day of life, the patient presented with tachypnea, hyperglycemia, and decreased serum levels of C-peptide and insulin. Continuous subcutaneous infusion of insulin and continuous glucose monitoring were well tolerated. The patient showed a normal growth pattern, with no hyperglycemic or hypoglycemic episodes at 6 months of age. As it is rare and often asymptomatic, hyperglycemia may be attributed to various factors, including intrauterine environment, perinatal stress, and diverse genetic background. Therefore, consistent blood glucose monitoring and prompt early insulin therapy are crucial for any term newborns with persistent hyperglycemia, to prevent further diabetic complications. Moreover, continuous subcutaneous insulin infusion and the utilization of continuous glucose monitoring devices are the most effective and practical management strategies.

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참고문헌

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