대한방사성의약품학회지 (Journal of Radiopharmaceuticals and Molecular Probes)

  • 제7권1호
  • /
  • Pages.50-55
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  • 2021
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  • 2384-1583(pISSN)
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  • 2508-3848(eISSN)
대한방사성의약품학회 (Korean Society of Radiopharmaceuticals and Molecular Probes)
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Is it possible to treat COVID-19 pneumonia by low-dose radiation?

  • Jae Min Jeong (Departement of Nuclear Medicine, Seoul National University College of Medicine)
  • 투고 : 2021.06.11
  • 심사 : 2021.06.28
  • 발행 : 2021.06.30
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초록

Low-dose radiotherapy has been known to have anti-inflammatory activity and been used for treatment of pneumonia together with anti-serum and sulfanilamide. However, it rapidly discontinued after the development of various antibiotics showing outstanding effect. Recently, it was re-considered to treat COVID-19 which has very limited treatment such as remdesivir and dexamethasone. So, several studies of COVID-19 therapy using low-dose radiation were reported very recently. They showed that low-dose radiation of 0.5~1.5 Gy were useful for decreasing the oxygen consumption and hospitalization period of COVID-19 patients without adverse reaction. Radiopharmaceuticals such as [99mTc]Tc-macroaggregated albumin (MAA) also might be used for low-dose radiotherapy. Administration of vitamin D having anti-inflammatory effect would also be helpful for therapy with synergistic effect.

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과제정보

이 연구는 산업통상자원부(20001235)와 보건복지부(HI15C-3093-010017)의 연구비 지원을 받은 연구이며 다른 이해 관계는 없음을 밝힙니다.

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