DOI QR코드

DOI QR Code

Lethality-Associated Factors in Deliberate Self-Poisoning

  • Choi, In Young (Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine) ;
  • Kim, Sun-Young (Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center) ;
  • Chang, Jhin Goo (Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine) ;
  • Song, Hoo Rim (Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine) ;
  • Kim, Woo Jung (Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine) ;
  • Lee, Su Young (Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine) ;
  • Kim, Hyun-Soo (Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine) ;
  • Hong, Minha (Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine)
  • Received : 2020.08.19
  • Accepted : 2020.10.08
  • Published : 2021.01.01

Abstract

Objectives: Deliberate self-poisoning (DSP) is the most common suicide method and can be life-threatening. The purpose of this study was to investigate the factors related to the lethality of DSP and the characteristics of the adolescent group. Methods: A retrospective study was conducted on patients who had visited an academic hospital's regional emergency medical center between 2015 and 2018. The data reviewed through their medical records included sociodemographic factors, clinical variables, and psychiatric treatment. Four groups (Q1-Q4) were categorized by descriptive analysis using the risk-rescue rating scale. Results: A total of 491 patients were enrolled in this study. This study showed that high lethality had statistically significant associations with male sex, older age, admitting suicidal intentions, and the use of herbicides for suicide. Logistic regression analyses showed a significant association between high-lethality and female [odds ratio (OR)=0.50, 95% confidence interval (CI)=0.30-0.81, p=0.01], non-psychiatric drugs (over-the-counter drug: OR=2.49, 95% CI=1.08-5.74, p=0.03; herbicide: OR=8.65, 95% CI=3.91-19.13, p<0.01), and denial of suicide intent (OR=0.28, 95% CI=0.15-0.55, p<0.01). Conclusion: This study showed the clinical factors associated with the high lethality of DSP and suggested that efforts were needed to care for and thoroughly examine patients with DSP.

Keywords

Acknowledgement

This study was supported by the Bumsuk Academic Research Fund in 2019. Part of the study results was presented as a poster at the Korean Neuropsychiatric Association's regional meeting on October 18, 2019.

References

  1. Ministry of Health and Welfare. 2018 National survey on suicide [cited 2020 Mar 20]. Available from URL: http://www.mohw.go.kr/react/jb/sjb030301vw.jsp.
  2. National Health Insurance Service Health Insurance Policy Institute. [Analysis of socio-economic costs of major diseases for setting priorities for health insurance policy]. Wonju: National Health Insurance Service Health Insurance Policy Institute;2017.
  3. World Health Organization. Preventing suicide: a global imperative. Luxembourg: World Health Organization;2014.
  4. Owens D, Horrocks J, House A. Fatal and non-fatal repetition of self-harm. Systematic review. Br J Psychiatry 2002;181:193-199. https://doi.org/10.1192/bjp.181.3.193
  5. Bergen H, Hawton K, Waters K, Ness J, Cooper J, Steeg S, et al. Premature death after self-harm: a multicentre cohort study. Lancet 2012;380:1568-1574. https://doi.org/10.1016/S0140-6736(12)61141-6
  6. Nock MK, Favazza AR. Nonsuicidal self-injury: definition and classification. In: Nock MK, editor. Understanding nonsuicidal self-injury: origins, assessment, and treatment. American Psychological Association;2009.
  7. Swannell SV, Martin GE, Page A, Hasking P, St John NJ. Prevalence of nonsuicidal self-injury in nonclinical samples: systematic review, meta-analysis and meta-regression. Suicide Life Threat Behav 2014;44:273-303. https://doi.org/10.1111/sltb.12070
  8. Spiller HA, Ackerman JP, Spiller NE, Casavant MJ. Sex- and agespecific increases in suicide attempts by self-poisoning in the United States among youth and young adults from 2000 to 2018. J Pediatr 2019;210:201-208. https://doi.org/10.1016/j.jpeds.2019.02.045
  9. Ministry of Health and Welfare; Korea Suicide Prevention Center. 2020 Suicide prevention white paper. Seoul: Korea Suicide Prevention Center;2020.
  10. Finkelstein Y, Macdonald EM, Hollands S, Hutson JR, Sivilotti ML, Mamdani MM, et al. Long-term outcomes following self-poisoning in adolescents: a population-based cohort study. Lancet Psychiatry 2015;2:532-539. https://doi.org/10.1016/S2215-0366(15)00170-4
  11. National Institute for Health and Care Excellence. Self-harm in over 8s: short-term management and prevention of recurrence [cited 2020 Mar 20]. Available from URL: https://www.nice.org.uk/guidance/cg16.
  12. Kim DW, Jeong KY, Kim KS. Psychological scales as predictors of emergency department hospitalizations in suicide attempters. Am J Emerg Med 2018;36:93-99. https://doi.org/10.1016/j.ajem.2017.07.038
  13. Weisman AD, Worden JW. Risk-rescue rating in suicide assessment. Arch Gen Psychiatry 1972;26:553-560. https://doi.org/10.1001/archpsyc.1972.01750240065010
  14. Patterson D, Fay J. Contemporary security management. 4th ed. Oxford: Butterworth-Heinemann;2017.
  15. Spooren D, Van Heeringen C, Jannes C. Strategies to increase compliance with out-patient aftercare among patients referred to a psychiatric emergency department: a multi-centre controlled intervention study. Psychol Med 1998;28:949-956. https://doi.org/10.1017/S0033291798006825
  16. Oh SH, Kim HJ, Kim SH, Kim YM, Park KN. Which deliberate self-poisoning patients are most likely to make high-lethality suicide attempts? Int J Ment Health Syst 2015;9:35. https://doi.org/10.1186/s13033-015-0028-4
  17. Jung WY, Park JM, Kang CJ, Lee BD, Lee YM. Clinical characteristics of completed versus non-completed suicide and re-attempt rates in 2-4 years. J Korean Neuropsychiatr Assoc 2009;48:488-495.
  18. Yeum TS, Kim B, Kim EY, Kim SH, Ha K, Ahn YM. Factors affecting suicide method lethality among suicide attempters in the Korea national suicide survey. J Nerv Ment Dis 2018;206:202-210. https://doi.org/10.1097/NMD.0000000000000735
  19. Gjelsvik B, Heyerdahl F, Holmes J, Lunn D, Hawton K. Is there a relationship between suicidal intent and lethality in deliberate selfpoisoning? Suicide Life Threat Behav 2017;47:205-216. https://doi.org/10.1111/sltb.12277
  20. Wu M, Zheng M, Zhang W, Suresh S, Schlecht U, Fitch WL, et al. Identification of drug targets by chemogenomic and metabolomic profiling in yeast. Pharmacogenet Genomics 2012;22:877-886. https://doi.org/10.1097/FPC.0b013e32835aa888
  21. Korea Law Information Center. [AGROCHEMICALS CONTROL ACT] [cited 2020 Mar 20]. Available from URL: https://www.law.go.kr/법령/농약관리법.
  22. Miller TR, Swedler DI, Lawrence BA, Ali B, Rockett IRH, Carlson NN, et al. Incidence and lethality of suicidal overdoses by drug class. JAMA Netw Open 2020;3:e200607. https://doi.org/10.1001/jamanetworkopen.2020.0607
  23. Gjelsvik B, Heyerdahl F, Hawton K. Prescribed medication availability and deliberate self-poisoning: a longitudinal study. J Clin Psychiatry 2012;73:e548-e554. https://doi.org/10.4088/JCP.11m07209
  24. Aseltine RH Jr, Schilling EA, James A, Glanovsky JL, Jacobs D. Age variability in the association between heavy episodic drinking and adolescent suicide attempts: findings from a large-scale, schoolbased screening program. J Am Acad Child Adolesc Psychiatry 2009;48:262-270. https://doi.org/10.1097/CHI.0b013e318195bce8
  25. Ali S, Rosychuk RJ, Dong KA, McGrath PJ, Newton AS. Temporal trends in pediatric mental health visits: using longitudinal data to inform emergency department health care planning. Pediatr Emerg Care 2012;28:620-625. https://doi.org/10.1097/PEC.0b013e31825cf93b
  26. Rojas SM, Skinner KD, Feldner MT, Rodante DE, Puppo S, Vidjen P, et al. Lethality of previous suicidal behavior among patients hospitalized for suicide risk predicts lethality of future suicide attempts. Suicide Life Threat Behav 2019;49:1431-1438. https://doi.org/10.1111/sltb.12538
  27. Wang LJ, Huang YC, Lee SY, Wu YW, Chen CK. Switching suicide methods as a predictor of completed suicide in individuals with repeated self-harm: a community cohort study in northern Taiwan. Aust N Z J Psychiatry 2015;49:65-73. https://doi.org/10.1177/0004867414553951
  28. Gairin I, House A, Owens D. Attendance at the accident and emergency department in the year before suicide: retrospective study. Br J Psychiatry 2003;183:28-33. https://doi.org/10.1192/bjp.183.1.28