The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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A review on the treatment of Herbal Medicine for asymptomatically infected COVID-19 patients

코로나-19 무증상 감염 환자의 한약 치료 방안에 대한 고찰

  • Jeong, Seonhyung (Department of Korean Medicine, College of Korean Medicine, Woosuk University) ;
  • Lee, Kyoungeun (Department of Korean Medicine, College of Korean Medicine, Woosuk University) ;
  • Jeong, Minjeong (Department of Pediatrics, College of Korean Medicine, Woosuk University) ;
  • Song, Mideok (Kyunghee Oriental Medical Clinic) ;
  • Jang, Insoo (Department of Internal Medicine, College of Korean Medicine, Woosuk University)
  • 정선형 (우석대학교 한의과대학 한의학과) ;
  • 이경은 (우석대학교 한의과대학 한의학과) ;
  • 정민정 (우석대학교 한의과대학, 한방소아과학교실) ;
  • 송미덕 (경희한의원) ;
  • 장인수 (우석대학교 한의과대학, 한방내과학교실)
  • Received : 2021.02.03
  • Accepted : 2021.02.18
  • Published : 2021.03.01
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Abstract

Objectives: Objective: The purpose of this study is to investigate the treatment of herbal medicine for patients with COVID-19 asymptomatic infections. Method: In English, search engines such as 'PubMed', 'Science Direct', and 'Cumulative Index to Nursing and Allied Health Literature (CINAHL)' were used. In Chinese, search engines such as 'China National Knowledge Infrastructure (CNKI)' and Wanfang were used. The keywords for the search engines were 'COVID-19', 'asymptomatic infection', 'Korean Medicine', 'traditional Chinese medicine', 'herbal medicine', and etc. Only clinical studies using herbal medicine for patients without fever or respiratory symptoms were selected. We excluded the cases that do not fit the research topic. Results: A total of 5 studies were finally selected. Among them, four of them used integrated herbal medicine and Western medicine, and one of the studies treated exclusively for herbal medicine. There were a total of seven prescriptions for herbal medicine used in the study. Outcome variables were used as following: lab test, nucleic acid conversion time, hospitalization period, chest CT, and etc. In the RCT study, herbal medicine and Western medicine decreased nucleic acid conversion time, average hospitalization time compared to the control group, but it was not statistically significant. No other adverse reactions were reported in all studies. Conclusion: According to the results, integrated herbal medicine and Western medicine might be an effective treatment for patients with COVID-19 asymptomatic infection reducing hospitalization period, time of nucleic acid turning negative. No severe adverse effects were reported. However, it is thought that better-designed research will be needed in the future.

Keywords

Acknowledgement

본 연구는 한국보건산업진흥원을 통해 보건복지부 「한의약선도기술개발사업」의 재정 지원을 받아 수행된 연구임 (HB16C0023).

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