Journal of Applied Biological Chemistry

  • 제64권2호
  • /
  • Pages.121-125
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  • 2021
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  • 1976-0442(pISSN)
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  • 2234-7941(eISSN)
한국응용생명화학회 (The Korean Society for Applied Biological Chemistry)
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연잎(Nelumbo nucifera) 추출물의 in vitro 생리활성

In vitro biological activities of lotus (Nelumbo nucifera) leaves extract

  • Park, Eun Jung (Department of Chemical Engineering, Chungwoon University) ;
  • Cho, Hye Won (Department of Chemical Engineering, Chungwoon University) ;
  • Park, Yu Jin (Department of Chemical Engineering, Chungwoon University) ;
  • In, Man-Jin (Department of Chemical Engineering, Chungwoon University) ;
  • Kim, Dong Chung (Department of Chemical Engineering, Chungwoon University)
  • 투고 : 2021.03.22
  • 심사 : 2021.04.19
  • 발행 : 2021.06.30
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초록

연잎(Nelumbo nucifera)의 60% (v/v) 에탄올 수용액 추출물의 항산화, 혈장 항응고 및 α-glucosidase 저해 효과를 in vitro에서 확인하였다. 연잎 추출물의 수율은 35.3±1.1%이었고, 폴리페놀 화합물 함량은 186.2±5.2 ㎍ gallic acid equivalents/mg으로 나타났다. 연잎 추출물은 농도에 비례하여 유리라디칼, 양이온라디칼 및 아질산염을 효과적으로 소거하였고 뛰어난 환원력을 보유하고 있었다. 또한 연잎 추출물은 농도 의존적으로 우수한 혈장 항응고 및 α-glucosidase 저해 활성을 나타내었다.

Antioxidative, anticoagulant, and α-glucosidase inhibitory effects of 60% (v/v) ethanolic extract from lotus (Nelumbo nucifera) leaves were investigated in vitro. The yield and polyphenol content of the lotus leaves extract were 35.3±1.1% and 186.2±5.2 ㎍ gallic acid equivalents/mg, respectively. The lotus leaves extract effectively scavenged free and cation radicals, and nitrite in a concentration-dependent manner, and possessed potent reducing power. The lotus leaves extract had remarkable anticoagulant and α-glucosidase inhibitory activities as a function of the extract concentration.

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피인용 문헌

  1. Antioxidant potential of root extracts of Panax ginseng and Panax notoginseng vol.64, pp.4, 2021, https://doi.org/10.3839/jabc.2021.055