DOI QR코드

DOI QR Code

Next-Generation Biomedical Devices via MicroLEDs

마이크로LED를 응용한 차세대 생체 치료 소자 개발

  • Lee, Han Eol (Division of Advanced Materials Engineering, Jeonbuk National University)
  • Received : 2021.04.06
  • Accepted : 2021.04.14
  • Published : 2021.07.01

Abstract

With the advent of the IoT (internet of things) era, there has been discussion on how to efficiently use various information from daily life. In academic and industrial society, various smart devices such as smart watches, smart phones, and smart glasses have been developed and commercialized for narrowing the physical/psychological distance with user information. According to recent developments of smart devices, the contemporary people have desired to check their body information and treat disease by themselves. According to the needs of the time, biological researches by phototherapy/monitoring have been actively conducted. Among various light sources, microLEDs have been spotlighted due to their superior optoelectric properties and stability. In this paper, we would like to review the state-of-the research results on the next-generation biological therapy devices via microLEDs.

Keywords

References

  1. S. Fatima, A. Haleem, S. Bahl, M. Javaid, S. K. Mahla, and S. Singh, Mater. Today: Proc., 45, 4844 (2021). [DOI: https://doi.org/10.1016/j.matpr.2021.01.305]
  2. O. Arias, J. Wurm, K. Hoang, and Y. Jin, IEEE Trans. Multi-Scale Comput. Syst., 1, 99 (2015). [DOI: https://doi.org/10.1109/TMSCS.2015.2498605]
  3. C. Yan, Y. Gao, S. Zhao, S. Zhang, Y. Zhou, W. Deng, Z. Li, G. Jiang, L. Jin, G. Tian, T. Yang, X. Chu, D. Xiong, Z. Wang, Y. Li, W. Yang, and J. Chen, Nano Energy, 67, 104235 (2020). [DOI: https://doi.org/10.1016/j.nanoen.2019.104235]
  4. S. B. Jeon, S. J. Park, W. G. Kim, I. W. Tcho, I. K. Jin, J. K. Han, D. Kim, and Y. K. Choi, Nano Energy, 53, 596 (2018). [DOI: https://doi.org/10.1016/j.nanoen.2018.09.024]
  5. T. He, H. Wang, J. Wang, X. Tian, F. Wen, Q. Shi, J. S. Ho, and C. Lee, Adv. Sci., 6, 1901437 (2019). [DOI: https://doi.org/10.1002/advs.201901437]
  6. Q. Shi, Z. Zhang, T. Chen, and C. Lee, Nano Energy, 62, 355 (2019). [DOI: https://doi.org/10.1016/j.nanoen.2019.05.033]
  7. G. Tang, Q. Shi, Z. Zhang, T. He, Z. Sun, and C. Lee, Nano Energy, 81, 105582, (2021). [DOI: https://doi.org/10.1016/j.nanoen.2020.105582]
  8. X. Wang, Y. Zhang, X. Zhang, Z. Huo, X. Li, M. Que, Z. Peng, H. Wang, and C. Pan, Adv. Mater., 30, 1706738 (2018). [DOI: https://doi.org/10.1002/adma.201706738]
  9. M. Zhu, Z. Sun, Z. Zhang, Q. Shi, T. He, H. Liu, T. Chen, and C. Lee, Sci. Adv., 6, eaaz8693 (2020). [DOI: https://doi.org/10.1126/sciadv.aaz8693]
  10. T. Yang, X. Jiang, Y. Zhong, X. Zhao, S. Lin, J. Li, X. Li, J. Xu, Z. Li, and H. Zhu, ACS Sens., 2, 967 (2017). [DOI: https://doi.org/10.1021/acssensors.7b00230]
  11. Y. Fu, S. Zhao, L. Wang, and R. Zhu, Adv. Healthcare Mater., 8, 1900633 (2019). [DOI: https://doi.org/10.1002/adhm.201900633]
  12. H. Lee, E. Kim, Y. Lee, H. Kim, J. Lee, M. Kim, H. J. Yoo, and S. Yoo, Sci. Adv., 4, eaas9530 (2018). [DOI: https://doi.org/10.1126/sciadv.aas9530]
  13. Z. Lou, L. Wang, and G. Shen, Adv. Mater. Technol., 3, 1800444 (2018). [DOI: https://doi.org/10.1002/admt.201800444]
  14. S. Bobovych, F. Sayeed, N. Banerjee, R. Robucci, and R. P. Allen, Smart Health, 16, 100113 (2020). [DOI: https://doi.org/10.1016/j.smhl.2020.100113]
  15. G. T. Hwang, H. Park, J. H. Lee, S. K. Oh, K. I. Park, M. Byun, H. Park, G. Ahn, C. K. Jeong, K. No, H. S. Kwon, S. G. Lee, B. Joung, and K. J. Lee, Adv. Mater., 26, 4880 (2014). [DOI: https://doi.org/10.1002/adma.201400562]
  16. G. T. Hwang, Y. Kim, J. H. Lee, S. K. Oh, C. K. Jeong, D. Y. Park, J. Ryu, H. S. Kwon, S. G. Lee, B. Joung, D. Kim, and K. J. Lee, Energy Environ. Sci., 8, 2677 (2015). [DOI: https://doi.org/10.1039/C5EE01593F]
  17. G. T. Hwang, M. Byun, C. K. Jeong, and K. J. Lee, Adv. Healthcare Mater., 4, 646 (2015). [DOI: https://doi.org/10.1002/adhm.201400642]
  18. H. E. Lee, S. Kim, J. Ko, H. I. Yeom, C. W. Byun, S. H. Lee, D. J. Joe, T. H. Im, S. H. Ko Park, and K. J. Lee, Adv. Funct. Mater., 26, 6170 (2016). [DOI: https://doi.org/10.1002/adfm.201601296]
  19. M. Balu, G. Lentsch, D. Z. Korta, K. Konig, K. M. Kelly, B. J. Tromberg, and C. B. Zachary, Lasers Surg. Med., 49, 555 (2017). [DOI: https://doi.org/10.1002/lsm.22655]
  20. I. Y. Yanina, N. A. Navolokin, A. B. Bucharskaya, G. N. Maslyakova, and V. V. Tuchin, J. Biophotonics, 12, e201900117 (2019). [DOI: https://doi.org/10.1002/jbio.201900117]
  21. H. E. Lee, J. H. Shin, J. H. Park, S. K. Hong, S. H. Park, S. H. Lee, J. H. Lee, I. S. Kang, and K. J. Lee, Adv. Funct. Mater., 29, 1808075 (2019). [DOI: https://doi.org/10.1002/adfm.201808075]
  22. J. H. Park, H. E. Lee, C. K. Jeong, D. H. Kim, S. K. Hong, K. I. Park, and K. J. Lee, Nano Energy, 56, 531 (2019). [DOI: https://doi.org/10.1016/j.nanoen.2018.11.077]
  23. J. H. Shin, J. H. Park, J. Seo, T. H. Im, J. C. Kim, H. E. Lee, D. H. Kim, K. Y. Woo, H. Y. Jeong, Y. H. Cho, T. S. Kim, I. S. Kang, and K. J. Lee, Adv. Mater., 33, 2007186 (2021). [DOI: https://doi.org/10.1002/adma.202007186]
  24. G. J. Woodgate and J. Harrold, J. Soc. Inf. Disp., 49, 1559 (2018). [DOI: https://doi.org/10.1002/sdtp.12285]
  25. T. I. Kim Y. H. Jung, J. Song, D. Kim, Y. Li, H. S. Kim, I. S. Song, J. J. Wierer, H. A. Pao, Y. Huang, and J. A. Rogers, Small, 8, 1643 (2012). [DOI: https://doi.org/10.1002/smll.201200382]
  26. R. H. Kim, M. H. Bae, D. G. Kim, H. Cheng, B. H. Kim, D. H. Kim, M. Li, J. Wu, F. Du, H. S. Kim, S. Kim, D. Estrada, S. W. Hong, Y. Huang, E. Pop, and J. A. Rogers, Nano Lett., 11, 3881 (2011). [DOI: https://doi.org/10.1021/nl202000u]
  27. V. R. Marinov, O. Swenson, Y. Atanasov, and N. Schneck, Microelectron. Eng., 101, 23 (2013). [DOI: https://doi.org/10.1016/j.mee.2012.08.016]
  28. V. Marinov, O. Swenson, R. Miller, F. Sarwar, Y. Atanasov, M. Semler, and S. Datta, IEEE Trans. Compon., Packag., Manuf. Technol., 2, 569 (2012). [DOI: https://doi.org/10.1109/TCPMT.2011.2176941]
  29. R. Miller, V. Marinov, O. Swenson, Z. Chen, and M. Semler, IEEE Trans. Components, Packag. Manuf. Technol., 2, 971 (2012). [DOI: https://doi.org/10.1109/TCPMT.2012.2183594]
  30. C. K. Jeong, K. I. Park, J. H. Son, G. T. Hwang, S. H. Lee, D. Y. Park, H. E. Lee, H. K. Lee, M. Byuna, and K. J. Lee, Energy Environ. Sci., 7, 4035 (2014). [DOI: https://doi.org/10.1039/C4EE02435D]
  31. S. H. Lee, J. Kim, J. H. Shin, H. E. Lee, I. S. Kang, K. Gwak, D. S. Kim, D. Kim, and K. J. Lee, Nano Energy, 44, 447 (2018). [DOI: https://doi.org/10.1016/j.nanoen.2017.12.011]
  32. G. T. Hwang, H. Park, J. H. Lee, S. K. Oh, K. I. Park, M. Byun, H. Park, G. Ahn, C. K. Jeong, K. No, H. S. Kwon, S. G. Lee, B. Joung, and K. J. Lee, Adv. Mater., 26, 4880 (2014). [DOI: https://doi.org/10.1002/adma.201400562]
  33. G. T. Hwang, Y. Kim, J. H. Lee, S. K. Oh, C. K. Jeong, D. Y. Park, J. Ryu, H. S. Kwon, S. G. Lee, B. Joung, D. Kim, and K. J. Lee, Energy Environ. Sci., 8, 2677 (2015). [DOI: https://doi.org/10.1039/C5EE01593F]
  34. Q. Yun, Y. Cheng, J. Cai, X. Zhao, Y. Ouyang, W. E. Yuan, and C. Fan, Regener. Med., 14, 969 (2019). [DOI: https://doi.org/10.2217/rme-2018-0079]
  35. K. Kim, M. Voroslakos, J. P. Seymour, K. D. Wise, G. Buzsaki, and E. Yoon, Nat. Commun., 11, 2063 (2020). [DOI: https://doi.org/10.1038/s41467-020-15769-w]
  36. W. S. Kim, S. Hong, M. Gamero, V. Jeevakumar, C. M. Smithhart, T. J. Price, R. D. Palmiter, C. Campos, and S. I. Park, Nat. Commun., 12, 157 (2021). [DOI: https://doi.org/10.1038/s41467-020-20421-8]
  37. A. Dieter, C. J. Duque-Afonso, V. Rankovic, M. Jeschke, and T. Moser, Nat. Commun., 10, 1962 (2019). [DOI: https://doi.org/10.1038/s41467-019-09980-7]
  38. H. E. Lee, J. H. Choi, S. H. Lee, M. Jeong, J. H. Shin, D. J. Joe, D. H. Kim, C. W. Kim, J. H. Park, J. H. Lee, D. Kim, C. S. Shin, and K. J. Lee, Adv. Mater., 30, 1800649 (2018). [DOI: https://doi.org/10.1002/adma.201800649]
  39. H. E. Lee, J. H. Park, D. Jang, J. H. Shin, T. H. Im, J. H. Lee, S. K. Hong, H. S. Wang, M. S. Kwak, M. Peddigari, C. K. Jeong, Y. Min, C. H. Park, J. J. Choi, J. Ryu, W. H. Yoon, D. Kim, K. J. Lee, and G. T. Hwang, Nano Energy, 75, 104951 (2020). [DOI: https://doi.org/10.1016/j.nanoen.2020.104951]
  40. H. E. Lee, S. H. Lee, M. Jeong, J. H. Shin, Y. Ahn, D. Kim, S. H. Oh, S. H. Yun, and K. J. Lee, ACS Nano, 12, 9587 (2018). [DOI: https://doi.org/10.1021/acsnano.8b05568]
  41. Y. Zhao, C. Liu, Z. Liu, W. Luo, L. Li, X. Cai, D. Liang, Y. Su, H. Ding, Q. Wang, L. Yin, J. Guan, M. Luo, and X. Sheng, IEEE Trans. Electron Devices, 66, 785 (2019). [DOI: https://doi.org/10.1109/TED.2018.2882397]
  42. H. E. Lee, D. Lee, T. I. Lee, J. H. Shin, G. M. Choi, C. Kim, S. H. Lee, J. H. Lee, Y. H. Kim, S. M. Kang, S. H. Park, I. S. Kang, T. S. Kim, B. S. Bae, and K. J. Lee, Nano Energy, 55, 454 (2019). [DOI: https://doi.org/10.1016/j.nanoen.2018.11.017]
  43. J. Kim, P. Gutruf, A. M. Chiarelli, S. Y. Heo, K. Cho, Z. Xie, A. Banks, S. Han, K. I. Jang, J. W. Lee, K. T. Lee, X. Feng, Y. Huang, M. Fabiani, G. Gratton, U. Paik, and J. A. Rogers, Adv. Funct. Mater., 27, 1604373 (2017). [DOI: https://doi.org/10.1002/adfm.201604373]
  44. J. Kim, G. A. Salvatore, H. Araki, A. M. Chiarelli, Z. Xie, A. Banks, X. Sheng, Y. Liu, J. W. Lee, K. I. Jang, S. Y. Heo, K. Cho, H. Luo, B. Zimmerman, J. Kim, L. Yan, X. Feng, S. Xu, M. Fabiani, G. Gratton, Y. Huang, U. Paik, and J. A. Rogers, Sci. Adv., 2, e1600418 (2016). [DOI: https://doi.org/10.1126/sciadv.1600418]
  45. R. H. Kim, D. H. Kim, J. Xiao, B. H. Kim, S. I. Park, B. Panilaitis, R. Ghaffari, J. Yao, M. Li, Z. Liu, V. Malyarchuk, D. G. Kim, A. P. Le, R. G. Nuzzo, D. L. Kaplan, F. G. Omenetto, Y. Huang, Z. Kang, and J. A. Rogers, Nat. Mater., 9, 929 (2010). [DOI: https://doi.org/10.1038/nmat2879]
  46. S. Y. Lee, K. I. Park, C. Huh, M. Koo, H. G. Yoo, S. Kim, C. S. Ah, G. Y. Sung, and K. J. Lee, Nano Energy, 1, 145 (2012). [DOI: https://doi.org/10.1016/j.nanoen.2011.07.001]
  47. H. E. Lee, J. H. Shin, S. H. Lee, J. H. Lee, S. H. Park, and K. J. Lee, Proc. Light-Emitting Devices, Materials, and Applications (SPIE OPTO, San Francisco, USA, 2019) p. 109100F. [DOI: https://doi.org/10.1117/12.2506926]