Current Optics and Photonics

Optical Society of Korea (한국광학회)
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Analysis of the Scattering Coefficients of Microspheres Using Spectroscopic Optical Coherence Tomography

  • Song, Woosub (Medical & Bio Photonics Research Center, Korea Photonics Technology Institute) ;
  • Lee, Seung Seok (Department of Physics, Chosun University) ;
  • Lee, Byeong-il (Medical & Bio Photonics Research Center, Korea Photonics Technology Institute) ;
  • Choi, Eun Seo (Department of Physics, Chosun University)
  • Received : 2021.01.18
  • Accepted : 2021.03.22
  • Published : 2021.06.25
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Abstract

We propose a characterization method for the scattering property of microspheres using spectroscopic optical coherence tomography (OCT). To prove the effectiveness of the proposed method, we prepare solutions of different concentrations using microspheres ranging from 28 to 2300 nm in diameter. Time-frequency analysis is performed on the measured interference spectrum of each solution, and the resulting spectroscopic information is converted into histograms for centroid wavelengths. The histograms present a very sensitive response to changes in the concentration and size of microspheres. We classify them into three categories according to their characteristics. When the histogram of each category is replaced with the corresponding calculated value of the scattering coefficient, each category is mapped to a different scattering-coefficient region. It is expected that the proposed method could be used to investigate the optical characteristics of a biological sample from OCT images, which would be helpful for optical diagnostic and therapeutic applications.

Keywords

Acknowledgement

This work was supported the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (grant no. NRF-2017R1A2B2009732).

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