DOI QR코드

DOI QR Code

Langerhans Cell Histiocytosis of the Clavicle in a 50-Year-Old Male: A Case Report

50세 남자에게서 발견된 쇄골의 랑게르한스 세포 조직구증: 증례 보고

  • Changhyun Park (Department of Radiology, Ilsan Paik Hospital, Inje University) ;
  • Yong Hoon Kim (Department of Radiology, Ilsan Paik Hospital, Inje University) ;
  • Soon Joo Cha (Department of Radiology, Ilsan Paik Hospital, Inje University) ;
  • Ji-Ye Kim (Department of Pathology, Ilsan Paik Hospital, Inje University)
  • 박창현 (인제대학교 일산백병원 영상의학과) ;
  • 김용훈 (인제대학교 일산백병원 영상의학과) ;
  • 차순주 (인제대학교 일산백병원 영상의학과) ;
  • 김지예 (인제대학교 일산백병원 병리과)
  • Received : 2020.06.05
  • Accepted : 2020.10.15
  • Published : 2021.07.01

Abstract

Langerhans cell histiocytosis (LCH) is a rare condition that usually occurs in children and commonly affects the skeletal system. It is extremely rare in adults, especially in the clavicles. In this report, we describe a pathologically confirmed case of LCH in the clavicle of a 50-year-old male. We report various radiological findings, such as plain radiography, CT, MR, and PET-CT, along with a review of the literature.

랑게르한스 세포 조직구증은 희귀한 질환으로 일반적으로 근골격계를 침범하며, 대부분 소아에게서 발생하고 성인의 쇄골에서 발병하는 경우는 극히 드물다. 이 증례 보고는 50세 남자에게서 영상학적으로 발견되어 병리학적으로 확진된 쇄골의 랑게르한스 세포 조직구증의 사례이다. 또한 저자들은 문헌고찰과 함께 단순촬영, 컴퓨터단층촬영, 자기공명영상법, 그리고 양전자방출단층촬영-컴퓨터단층촬영 영상 등의 다양한 영상검사 소견을 보고하고자 한다.

Keywords

References

  1. Weitzman S, Jaffe R. Uncommon histiocytic disorders: the non-Langerhans cell histiocytoses. Pediatr Blood Cancer 2005;45:256-264 https://doi.org/10.1017/CBO9780511545252.016
  2. Udaka T, Susa M, Kikuta K, Nishimoto K, Horiuchi K, Sasaki A, et al. Langerhans cell histiocytosis of the clavicle in an adult: a case report and review of the literature. Case Rep Oncol 2015;8:426-431 https://doi.org/10.1159/000441415
  3. Franklin JL, Parker JC, King HA. Nontraumatic clavicle lesions in children. J Pediatr Orthop 1987;7:575-578 https://doi.org/10.1097/01241398-198709000-00014
  4. Kapoor S, Tiwari A, Kapoor S. Primary tumours and tumorous lesions of clavicle. Int Orthop 2008;32:829-834 https://doi.org/10.1007/s00264-007-0397-7
  5. Parikh SN, Desai VR, Gupta A, Anton CG. Langerhans cell histiocytosis of the clavicle in a 13-year-old boy. Case Rep Orthop 2014;2014:510287
  6. Arico M, Girschikofsky M, Genereau T, Klersy C, McClain K, Grois N, et al. Langerhans cell histiocytosis in adults. Report from the International Registry of the Histiocyte Society. Eur J Cancer 2003;39:2341-2348 https://doi.org/10.1016/S0959-8049(03)00672-5
  7. Tsuchie H, Okada K, Nagasawa H, Yano M, Nanjyo H, Shimada Y. Langerhans cell histiocytosis of the sternum. Ups J Med Sci 2009;114:121-125 https://doi.org/10.1080/03009730802642360
  8. Wester SM, Beabout JW, Unni KK, Dahlin DC. Langerhans' cell granulomatosis (histiocytosis X) of bone in adults. Am J Surg Pathol 1982;6:413-426 https://doi.org/10.1097/00000478-198207000-00003
  9. Song YS, Lee IS, Yi JH, Cho KH, Kim DK, Song JW. Radiologic findings of adult pelvis and appendicular skeletal Langerhans cell histiocytosis in nine patients. Skeletal Radiol 2011;40:1421-1426 https://doi.org/10.1007/s00256-010-1078-y
  10. Christopher Z, Binitie O, Henderson-Jackson E, Perno J, Makanji RJ. Langerhans cell histiocytosis of bone in an adult: a case report. Radiol Case Rep 2018;13:310-314 https://doi.org/10.1016/j.radcr.2017.11.020