Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Selective Copper-Catalyzed Azidation and Amination of Aryl Halides with Sodium Azide

구리 촉매에 의한 할로젠화 아릴과 아지도 소듐의 선택적 아지드화 및 아민화 반응

  • Paik, Seunguk (Department of Chemical Engineering, Keimyung University)
  • 백승욱 (계명대학교 화학공학과)
  • Received : 2021.02.09
  • Accepted : 2021.03.12
  • Published : 2021.04.10
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Abstract

A rapid and selective copper-catalyzed amination of aryl halides with sodium azide was established by using 10 mol % of CuI, and 20 mol % of N,N'-dimethylethylenediamine in DMSO under microwave irradiation for 10 min. The catalytic system with 4-substituted aryl iodides was found to be the most effective leading to a nearly complete conversion.

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References

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