Advances in nano research

  • 제11권6호
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  • Pages.667-678
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  • 2021
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  • 2287-237X(pISSN)
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  • 2287-2388(eISSN)
테크노프레스 (Techno-Press)
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DOI QR코드

DOI QR Code

Drug adsorption and anti-microbial activity of functionalized multiwalled carbon nanotubes

  • Saxena, Megha (Department of Chemistry, Kirori Mal College, University of Delhi) ;
  • Mittal, Disha (Nanobiotech Lab, Department of Zoology, Kirori Mal College, University of Delhi) ;
  • Boudh, Richa (Department of Chemistry, Kirori Mal College, University of Delhi) ;
  • Kumar, Kapinder (Nanobiotech Lab, Department of Zoology, Kirori Mal College, University of Delhi) ;
  • Verma, Anita K. (Nanobiotech Lab, Department of Zoology, Kirori Mal College, University of Delhi) ;
  • Saxena, Reena (Department of Chemistry, Kirori Mal College, University of Delhi)
  • 투고 : 2020.11.23
  • 심사 : 2021.10.31
  • 발행 : 2021.12.25
⟨ 이전 논문 다음 논문 ⟩

초록

Multiwalled carbon nanotubes (MWCNTs) were first oxidized (O-CNTs) to introduce carboxylic group and then further functionalized (F-CNTs) with m-phenylenediamine, which was confirmed by FTIR and SEM. It was used as an effective adsorbent for the adsorptive removal of diclofenac drug from water. Under optimum conditions of pH 6, stirring speed 600 rpm, the maximum adsorption capacity obtained was 532 mg g-1 which is superior to the values reported in literature. The adsorption was quite rapid as 25 mg L-1 drug solution was adsorbed in only 3 minutes of contact time with 10 mg of adsorbent dose. The adsorption kinetics and isotherms were studied using various models to evaluate the adsorption process. The results showed that the data best fit in kinetics pseudo-second order and Langmuir isotherm model. Furthermore, the oxidized and functionalized MWCNTs were applied on gram-negative Escherichia coli and gram-positive Staphylococcus aureus using agar disc diffusion assay to validate their anti-microbial activity. Results were unique as both oxidized and functionalized MWCNTs were equally active against both E. coli and S. aureus. The newly synthesized F-CNTs have great potential in water treatment, with their dual action of removing drug and pathogens from water, makes it potential applicant to save environment.

키워드

과제정보

The authors are thankful to University of Delhi Innovation Project KMC 302 and Science and Engineering Research Board (SR/S1/IC-64/2012), Delhi, India for the financial support. The authors would also like to thank University Science Instrumentation Centre (USIC), University of Delhi, for providing instrumentation facility.

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