Parasites, Hosts and Diseases

  • 제58권4호
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  • Pages.467-473
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  • 2020
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  • 2982-5164(pISSN)
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  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
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Larval Gnathostomes and Spargana in Chinese Edible Frogs, Hoplobatrachus rugulosus, from Myanmar: Potential Risk of Human Infection

  • Chai, Jong-Yil (Institute of Parasitic Diseases, Korea Association of Health Promotion) ;
  • Jung, Bong-Kwang (Institute of Parasitic Diseases, Korea Association of Health Promotion) ;
  • Ryu, in-Youp (Institute of Parasitic Diseases, Korea Association of Health Promotion) ;
  • Kim, Hyun-Seung (Institute of Parasitic Diseases, Korea Association of Health Promotion) ;
  • Hong, Sung-Jong (Department of Environmental Medical Biology, Chung-Ang University College of Medicine) ;
  • Htoon, Thi Thi (National Health Laboratory) ;
  • Tin, Htay Htay (National Health Laboratory) ;
  • Na, Byoung-Kuk (Department of Parasitology and Tropical Medicine, and Institute of Health Sciences, Gyeongsang National University College of Medicine) ;
  • Sohn, Woon-Mok (Department of Parasitology and Tropical Medicine, and Institute of Health Sciences, Gyeongsang National University College of Medicine)
  • 투고 : 2020.07.03
  • 심사 : 2020.07.27
  • 발행 : 2020.08.31
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초록

Chinese edible frogs, Hoplobatrachus rugulosus, were examined to estimate the potential risks of human gnathostomiasis and sparganosis in Myanmar. A total of 20 frogs were purchased in a local market of Yangon and examined with naked eyes and the artificial digestion method after skin peeling in June 2018 and June 2019. Larvae of gnathostomes and Spirometra (=spargana) were detected in 15 (75.0%) and 15 (75.0%) frogs with average intensities of 10.5 and 6.3 larvae per infected frog, respectively. Gnathostome larvae were 2.75-3.80 (av. 3.30) mm long and 0.29-0.36 (0.33) mm wide. They had a characteristic head bulb with 4 rows of hooklets, a muscular long esophagus, and 2 pairs of cervical sac. The mean number of hooklets were 41, 44, 47, and 50 on the 1st, 2nd, 3rd, and 4th row, respectively. Collected spargana were actively moving, particularly with the scolex part, and have ivory-white color and variable in size. Conclusively, it has been first confirmed that Chinese edible frogs, H. rugulosus, are highly infected with larval gnathostomes and spargana in this study. Consuming these frogs is considered a potential risk of human gnathostomiasis and sparganosis in Myanmar.

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참고문헌

  1. Beaver PC, Jung RC, Cupp EW. Clinical Parasitology. 9th ed. Philadelphia, USA. Lea & Febiger. 1984, pp 340-343 and 499-502.
  2. Fan PC. Cutaneous larva migrans in Taiwan: Report of two cases and a brief review of human sparganosis and gnathostomiasis. Chin J Parasitol 1999; 12: 61-69.
  3. Kukushima T, Yamane Y. How does the sparganosis occur? Parasitol Today 1999; 15: 124.
  4. Liu Q, Li MW, Wang ZD, Zhao GH, Zhu XQ. Human sparganosis, a neglected food borne zoonosis. Lancet Infect Dis 2015; 15: 1226-1235. https://doi.org/10.1016/S1473-3099(15)00133-4
  5. Miyazaki I. Section III. Nematode Zoonoses. 33. Gnathostomiasis. An Illustrated Book of Helminthic Zoonoses. Tokyo, Japan. International Medical Foundation of Japan. 1991, pp 368-409.
  6. Herman JS, Chiodini PL. Gnathostomiasis, another emerging imported disease. Clin Microbiol Rev 2009; 22: 484-492. https://doi.org/10.1128/CMR.00003-09
  7. Gyi K. Intra-ocular gnathostomiasis. Br J Ophthalmol 1960; 44: 42-45. https://doi.org/10.1136/bjo.44.1.42
  8. Khin T. Intra-ocular gnathostomiasis. Br J Ophthalmol 1968; 52: 57-60. https://doi.org/10.1136/bjo.52.1.57
  9. Nomura Y, Nagakura K, Kagei N, Tsutsumi Y, Araki K, Sugawara. M. Gnathostomiasis possibly caused by Gnathostoma malaysiae. Tokai J Exp Clin Med 2000; 25: 1-6.
  10. Chai JY, Han ET, Shin EH, Park JH, Chu JP, Hirota M, Nakamura F, Nawa Y. An outbreak of gnathostomiasis among Korean emigrants in Myanmar. Am J Trop Med Hyg 2003; 69: 67-73. https://doi.org/10.4269/ajtmh.2003.69.67
  11. Develoux M, Dekumyoy P, Baygon E, Aractingi S. Imported gnathostomiasis acquired in Myanmar. Med Mal Infect 2006; 36: 340-342 (in French). https://doi.org/10.1016/j.medmal.2006.01.011
  12. Wai AP, Maw WW, Moe AC, Boonmars T, Nawa Y. Human gnathostomiasis in Myanmar: A review of local literature. Southeast Asian J Trop Med Public Health 2018; 49: 543-548.
  13. Jung BK, Lee JJ, Pyo KH, Kim HJ, Jeong HG, Yoon CH, Lee SH, Shin EH, Chai JY. Detection of Gnathostoma spinigerum third-stage larvae in snakeheads purchased from a central part of Myanmar. Korean J Parasitol 2008; 46: 285-288. https://doi.org/10.3347/kjp.2008.46.4.285
  14. Chai JY, Sohn WM, Na BK, Park JB, Jeoung HG, Hoang EH, Htoon TT, Tin HH. Larval Gnathostoma spinigerum detected in Asian swamp eels, Monopterus albus, purchased from a local market in Yangon, Myanmar. Korean J Parasitol 2015; 53: 619-625. https://doi.org/10.3347/kjp.2015.53.5.619
  15. Li MW, Lin HY, Xie WT, Gao MJ, Huang ZW, Wu JP, Li C, Lin RQ, Zhu XQ. Enzootic sparganosis in Guangdong, People's Republic of China. Emerg Infect Dis 2009; 15: 1317-1318. https://doi.org/10.3201/eid1508.090099
  16. Li MW, Song HQ, Li C, Lin HY, Xie WT, Lin RQ, Zhu XQ. Sparganosis in mainland China. Int J Infect Dis 2011; 15: e154-156. https://doi.org/10.1016/j.ijid.2010.10.001
  17. Kim JG, Ahn CS, Sohn WM, Nawa Y, Kong Y. Human sparganosis in Korea. J Korean Med Sci 2018; 33: e273. https://doi.org/10.3346/jkms.2018.33.e273
  18. Wiwanitkit V. A review of human sparganosis in Thailand. Int J Infect Dis 2005; 9: 312-316. https://doi.org/10.1016/j.ijid.2004.08.003
  19. Anantaphruti MT, Nawa Y, Vanvanitchai Y. Human sparganosis in Thailand: an overview. Acta Trop 2011; 118: 171-176. https://doi.org/10.1016/j.actatropica.2011.03.011
  20. Cui J, Wang Y, Zhang X, Lin XM, Zhang HW, Wang ZQ, Chen JX. A neglected risk for sparganosis: eating live tadpoles in central China. Infect Dis Poverty 2017; 6: 58-61. https://doi.org/10.1186/s40249-017-0265-7
  21. Kim CH. The infection status of sparganum and Gnathostoma in frogs of southern part of Korea. Korean J Parasitol 1983; 21: 83-86 (in Korean). https://doi.org/10.3347/kjp.1983.21.1.83
  22. Mastura AB, Ambu S, Hasnah O, Rosli R. Spargana infection of frogs in Malaysia. Southeast Asian J Trop Med Public Health 1996; 27: 51-52.
  23. Ooi HK, Chang SL, Huang CC, Kawakami Y, Uchida A. Survey of Spirometra erinaceieuropaei in frogs in Taiwan and its experimental infection in cats. J Helminthol 2000; 74: 173-176. https://doi.org/10.1017/S0022149X0000024X
  24. Qi RL, Liu YF, Wang H, Liu HA, Liang SJ, Shen HX, Li XM, Chen XY, Ma CL, Chen DX. An investigation on infection of sparganum of Spirometra mansoni in frogs from Guangzhou City from 2004 to 2007. J Trop Med 2008; 8: 1178-1179. https://doi.org/10.3969/j.issn.1672-3619.2008.11.025
  25. Xu WM, Tang Y, Wang J, Yang Y, Fang SY, Zhu SJ, et al. Survey of Sparganum mansoni infection in frogs and snakes in Hangzhou. Dis Surveil 2009; 24: 612-613.
  26. Wei T, Zhang X, Cui J, Liu LN, Jiang P, Wang ZQ. Levels of sparganum infections and phylogenetic analysis of the tapeworm Spirometra erinaceieuropaei sparganum in wild frogs from Henan province in central China. J Helminthol 2015; 89: 433-438. https://doi.org/10.1017/S0022149X14000248
  27. Hong Q, Feng J, Liu H, Li X, Gong L, Yang Z, Yang W, Liang X, Zheng R, Cui Z, Wang W, Chen D. Prevalence of Spirometra mansoni in dogs, cats, and frogs and its medical relevance in Guangzhou, China. Int J Infect Dis 2016; 53: 41-45.
  28. Jeon HK, Park HS, Lee DM, Choe SJ, Kang YS, Bia MM, Lee SH, Sohn WM, Hong SJ, Chai JY, Eom KS. Genetic and morphologic identification of Spirometra ranarum in Myanmar. Korean J Parasitol 2018; 56: 275-280. https://doi.org/10.3347/kjp.2018.56.3.275
  29. Boonyasiri A, Cheunsuchon P, Suputtamongkol Y, Yamasaki H, Sanpool O, Maleewong W, Intapan PM. Nine human sparganosis cases in Thailand with molecular identification of causative parasite species. Am J Trop Med Hyg 2014; 91: 389-393. https://doi.org/10.4269/ajtmh.14-0178
  30. Information on Chinese edible frog, Hoplobatrachus rugulosus [Internet]; Available from: http://en.wikipedia.org.

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