Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Antioxidant, Inhibitory on NO Production and In-vitro Cell Regeneration Effects of Pink-aloe

핑크-알로에의 항산화, NO 생성 억제 및 세포 재생 효과

  • Lee, Kyung Ju (Skin & Natural Products Lab., Kolmar Korea Co., Ltd.) ;
  • Jang, Wookju (Skin & Natural Products Lab., Kolmar Korea Co., Ltd.) ;
  • Kim, You Ah (Skin & Natural Products Lab., Kolmar Korea Co., Ltd.) ;
  • Park, Byoung Jun (Skin & Natural Products Lab., Kolmar Korea Co., Ltd.) ;
  • Kang, Hakhee (Skin & Natural Products Lab., Kolmar Korea Co., Ltd.)
  • 이경주 (한국콜마(주) 피부천연물연구소) ;
  • 장욱주 (한국콜마(주) 피부천연물연구소) ;
  • 김유아 (한국콜마(주) 피부천연물연구소) ;
  • 박병준 (한국콜마(주) 피부천연물연구소) ;
  • 강학희 (한국콜마(주) 피부천연물연구소)
  • Received : 2020.06.12
  • Accepted : 2020.08.27
  • Published : 2020.09.30
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Abstract

Aloe vera (Aloe barbadensis Miller) has been used since ancient times to improve various skin diseases such as burns, wounds, and eczema. It has been reported that Aloe vera contains vitamin, enzyme, mineral, sugar, phenolic compound, fatty acid and amino acid. Aloe vera changes its color from green to red under the extreme thermal and arid climate to protect itself. These morphological changes induce variation of composition such as increasing of aloe-emodin content. Aloe-emodin is one of the major anthraquinone in aloe family plants. Since aloe-emodin contains a polyphenolic structure, this compound may be responsible for the reported antioxidant and anti-inflammatory effects of aloe. However, there is no research on the process of increasing the compounds of Aloe vera. Therefore, the purpose of this study is to develop a pink aloe manufacturing process that increases the aloe-emodin content and enhances the antioxidant and anti-inflammatory activities of aloe. As a result of heating aloe under appropriate conditions, pink aloe increased aloe-emodin content compared to general aloe, and exhibited effects such as increasing antioxidant activity, inhibiting NO production, and promoting cell regeneration. Through this study, the applicability of pink aloe as a new anti-aging material in the cosmetic field was confirmed.

알로에 베라(Aloe barbadensis Miller)는 예로부터 화상이나 상처, 습진 등의 다양한 피부 질환을 개선하기 위해 사용해 왔다. 이러한 효능은 알로에가 가지고 있는 비타민, 무기질, 당, 페놀 물질, 지방산. 아미노산 등의 다양한 성분에 의한 것으로 보고가 되었다. 알로에는 극한의 환경에서 스스로를 보호하기 위해서 성분을 변화시키며, 이로 인해 색깔이 녹색에서 적색으로 변화한다. Aloe-emodin은 알로에속 식물의 대표적인 페놀성 물질로 항산화 및 항염 활성을 나타낸다. 그러나 지금까지 알로에의 활성 물질인 알로에-에모딘을 증가시키고 알로에의 색상을 변화시키는 공정 개발에 대한 연구는 보고되지 않았다. 따라서 본 연구의 목적은 aloe-emodin 함량을 증가시키고 알로에의 항산화 및 항염 활성을 증대시키는 핑크 알로에 제조공정을 개발하는 것이다. 이를 위해 알로에를 적정 조건으로 가온한 결과 핑크 알로에는 일반 알로에 대비 aloe-emodin 함량이 증가하였으며, 항산화 활성 증대, NO 생성 억제, 세포 재생 촉진 등의 효과를 나타내었다. 본 연구를 통해 화장품 분야에서 핑크 알로에의 신규 항노화 소재로 활용성을 확인하였다.

Keywords

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