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마리화나 흡연으로 인해 발생한 젊은 연령 뇌경색 1례

A Case of Ischemic Stroke in Young Patient Associated with Marijuana Use

  • Ha, Sue Young (Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Kang, Dong-Wan (Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Lee, Seung-Hoon (Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine)
  • 투고 : 2019.07.15
  • 심사 : 2020.01.07
  • 발행 : 2020.06.30

초록

A 21-year-old female patient complaining of hemiparesis was diagnosed with right middle cerebral artery infarction. No risk factor was found, despite an extensive young-age stroke work-up, except her history of marijuana use. The patient had smoked marijuana for treating depression for more than five years. Magnetic resonance angiography showed multifocal intra- and extracranial stenoses, suggesting cannabinoid-induced vasculopathy. Since the use of illicit drugs has increased nationwide, physicians should consider it as a possible cause of a stroke due to an unknown etiology.

키워드

참고문헌

  1. Wolff V, Jouanjus E. Strokes are possible complications of cannabinoids use. Epilepsy Behav 2017;70:355-63. https://doi.org/10.1016/j.yebeh.2017.01.031
  2. Thanvi BR, Treadwell SD. Cannabis and stroke: is there a link? Postgrad Med J 2009;85:80-3. https://doi.org/10.1136/pgmj.2008.070425
  3. Thayakaran R, Adderley NJ, Sainsbury C, et al. Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study. BMJ 2019;366:l4892.
  4. Singh A, Saluja S, Kumar A, et al. Cardiovascular Complications of Marijuana and Related Substances: A Review. Cardiol Ther 2018;7:45-59. https://doi.org/10.1007/s40119-017-0102-x
  5. Wolff V, Armspach JP, Lauer V, et al. Cannabis-related Stroke Myth or Reality? Stroke 2013;44:558-63. https://doi.org/10.1161/strokeaha.112.671347
  6. Wolff V, Zinchenko I, Quenardelle V, et al. Characteristics and prognosis of ischemic stroke in young cannabis users compared with non-cannabis users. J Am Coll Cardiol 2015;66:2052-3. https://doi.org/10.1016/j.jacc.2015.08.867
  7. Mateo I, Pinedo A, Gomez-Beldarrain M, et al. Recurrent stroke associated with cannabis use. J Neurol Neurosurg Psychiatry 2005;76:435-7. https://doi.org/10.1136/jnnp.2004.042382
  8. Rumalla K, Reddy AY, Mittal MK. Recreational marijuana use and acute ischemic stroke: A population-based analysis of hospitalized patients in the United States. J Neurol Sci 2016;364:191-6. https://doi.org/10.1016/j.jns.2016.01.066
  9. Hemachandra D, McKetin R, Cherbuin N, et al. Heavy cannabis users at elevated risk of stroke:evidence from a general population survey. Aust NZ J Public Health 2016;40:226-30. https://doi.org/10.1111/1753-6405.12477
  10. Lee IH, Kim SM, Bae JC, et al. Cerebral Infarction Associated with Marijuana. Journal of the Korean Neurological Association 1999;17(2): 294-7.
  11. Jung JS, Park YW, Lee SA, et al. Ischemic Stroke after Use of Cannabis: a Case Report and Review of Literature. Investig Magn Reson Imaging 2018 Sep;22(3):168-71. https://doi.org/10.13104/imri.2018.22.3.168
  12. Korea Customs Service. Drug smuggling is blocked from the border at the customs. [cited 2018 July 16] Available from: URL: http://www.customs.go.kr/kcshome/
  13. Supreme Prosecutors' Office. 2017 A white paper of the illicit drugs chapter 3. [cited 2018 August 28] Available from: URL: http://www.spo.go.kr/spo/major/drug/data/drugbbs04.jsp
  14. Volpon LC, Sousa CLMM, Moreira SKK, et al. Multiple Cerebral Infarcts in a Young Patient Associated With Marijuana Use. J Addict Med 2017;11(5):405-7. https://doi.org/10.1097/adm.0000000000000326
  15. Simunek L, Krajina A, Herzig R, et al. Cerebral Infarction in Young Marijuana Smokers - Case Reports. Acta Medica (Hradec Kralove) 2018;61(2):74-7. https://doi.org/10.14712/18059694.2018.56
  16. Solimini R, Rotolo MC, Pichini S, et al. Neurological Disorders in Medical Use of Cannabis: An Update. CNS Neurol Disord Drug Targets 2017;16(5):527-33.