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Suicidality and Related Psychopathology across Different Stages of Schizophrenia

조현병의 질환단계에 따른 자살경향성과 정신병리의 관계

  • Joh, Euwon (Department of Mental Health Research, National Center for Mental Health) ;
  • Park, Kyeongwoo (Department of Clinical Psychology, National Center for Mental Health) ;
  • Lee, Dong-Kyun (Department of Mental Health Research, National Center for Mental Health) ;
  • Lee, Hyeongrae (Department of Mental Health Research, National Center for Mental Health) ;
  • Kim, Chul-Eung (Mental Health Research Institute, National Center for Mental Health) ;
  • Ryu, Seunghyong (Department of Psychiatry, Chonnam National University Medical School)
  • 조유원 (국립정신건강센터 정신보건연구과) ;
  • 박경우 (국립정신건강센터 임상심리과) ;
  • 이동균 (국립정신건강센터 정신보건연구과) ;
  • 이형래 (국립정신건강센터 정신보건연구과) ;
  • 김철응 (국립정신건강센터 정신건강연구소) ;
  • 류승형 (전남대학교 의과대학 정신건강의학교실)
  • Received : 2019.09.17
  • Accepted : 2019.11.03
  • Published : 2020.04.30

Abstract

Objectives: This study aimed to investigate suicidal behaviors and the related psychopathology across the different stages of schizophrenia. Methods: We recruited 131 patients with schizophrenia and categorized them into two groups, according to the duration of illness (DI) as follows: ≤10 years (n=39) and >10 years (n=92). Psychopathology and suicidality were assessed using the 18-item Brief Psychiatric Rating Scale (BPRS-18) and the suicidality module from the Mini-International Neuropsychiatric Interview, respectively. Results: One-quarter of the patients with a DI ≤10 years and nearly one-sixth of the patients with a DI >10 years experienced suicidal behaviors in the previous month. Suicidality scores were significantly associated with the "affect" factor scores of the BPRS-18 in patients with a DI ≤10 years (β=0.55, p=0.003) and with the "resistance" factor scores in patients with a DI of >10 years (β=0.29, p=0.006). Conclusion: The present study demonstrated that psychopathological factors were differentially associated with suicidality in patients with schizophrenia according to the illness stage. Our findings suggest that for effective suicide prevention, different approaches are required for the management of each stage of schizophrenia.

Keywords

Acknowledgement

본 연구는 2018년도 국립정신건강센터 정신건강연구소과제(R2018-B)의 지원을 받아 수행된 연구임.

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