References
- Luo Z, Zeng H, Ye Y, Liu L, Li S, Zhang J, et al. Safflower polysaccharide inhibits the proliferation and metastasis of MCF-7 breast cancer cell. Mol Med Rep. 2015;11:4611-4616. https://doi.org/10.3892/mmr.2015.3310
- Sitarz R, Skierucha M, Mielko J, Offerhaus GJA, Maciejewski R, Polkowski WP. Gastric cancer: epidemiology, prevention, classification, and treatment. Cancer Manag Res. 2018;10: 239-248. https://doi.org/10.2147/CMAR.S149619
- Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014;64:9-29. https://doi.org/10.3322/caac.21208
- Orditura M, Galizia G, Sforza V, Gambardella V, Fabozzi A, Laterza MM, et al. Treatment of gastric cancer. World J Gastroenterol. 2014;20:1635-1649. https://doi.org/10.3748/wjg.v20.i7.1635
- Sharma G, Kar S, Palit S, Das PK. 18beta-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells. J Cell Physiol. 2012;227:1923-1931. https://doi.org/10.1002/jcp.22920
- Xiao Y, Xu J, Mao C, Jin M, Wu Q, Zou J, et al. 18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha. J Biol Chem. 2010;285:1128-1137. https://doi.org/10.1074/jbc.M109.037705
-
Jayasooriya RG, Dilshara MG, Park SR, Choi YH, Hyun JW, Chang WY, et al.
$18{\beta}$ -Glycyrrhetinic acid suppresses TNF-${\alpha}$ induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the AKT-dependent NF-${\kappa}B$ pathway. Toxicol In Vitro. 2014;28:751-758. https://doi.org/10.1016/j.tiv.2014.02.015 - Lin D, Zhong W, Li J, Zhang B. Song G, Hu T. Involvement of BID translocation in glycyrrhetinic acid and 11-deoxy glycyrrhetinic acid-induced attenuation of gastric cancer growth. Nutr Cancer. 2014;66:463-473. https://doi.org/10.1080/01635581.2013.877498
- Agarwal MK, Iqbal M, Athar M. Inhibitory effect of 18beta-glycyrrhetinic acid on 12-O-tetradecanoyl phorbol-13-acetate-induced cutaneous oxidative stress and tumor promotion in mice. Redox Rep. 2005;10:151-157. https://doi.org/10.1179/135100005X57346
- Hoever G, Baltina L, Michaelis M, Kondratenko R, Baltina L, Tolstikov GA, et al. Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus. J Med Chem. 2005; 48:1256-1259. https://doi.org/10.1021/jm0493008
- Takeuchi R, Hiratsuka K, Arikawa K, Ono M, Komiya M, Akimoto Y, et al. Possible pharmacotherapy for nifedipine-induced gingival overgrowth: 18alpha-glycyrrhetinic acid inhibits human gingival fibroblast growth. Br J Pharmacol. 2016;173:913-924. https://doi.org/10.1111/bph.13410
-
Huang YC, Kuo CL, Lu KW, Lin JJ, Yang JL, Wu RS, et al.
$18{\alpha}$ -glycyrrhetinic acid induces apoptosis of HL-60 human leukemia cells through caspases- and mitochondriadependent signaling Pathways. Molecules. 2016;21:872. https://doi.org/10.3390/molecules21070872 - Yin SY, Wei WC, Jian FY, Yang NS. Therapeutic applications of herbal medicines for cancer patients. Evid Based Complement Alternat Med. 2013;2013;302426.
- Wang ZY, Nixon DW. Licorice and cancer. Nutr Cancer. 2001;39:1-11. https://doi.org/10.1207/S15327914nc391_1
- Nomura T, Fukai T. Phenolic constituents of licorice (Glycyrrhiza species). Fortschr Chem Org Naturst. 1998;73:1-158.
- Baltina LA. Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine. Curr Med Chem. 2003;10:155-171. https://doi.org/10.2174/0929867033368538
- Rackova L, Jancinova V, Petrikova M, Drabikova K, Nosal R, Stefek M, et al. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. Nat Prod Res. 2007;21:1234-1241. https://doi.org/10.1080/14786410701371280
- Thirugnanam S, Xu L, Ramaswamy K, Gnanasekar M. Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP. Oncol Rep. 2008;20:1387-1392.
- Niwa K, Lian Z, Onogi K, Yun W, Tang L, Mori H, et al. Preventive effects of glycyrrhizin on estrogen-related endometrial carcinogenesis in mice. Oncol Rep. 2007;17:617-622.
- Ikeda T, Yokomizo K, Okawa M, Tsuchihashi R, Kinjo J, Nohara T, et al. Anti-herpes virus type 1 activity of oleanane-type triterpenoids. Biol Pharm Bull. 2005;28: 1779-1781. https://doi.org/10.1248/bpb.28.1779
- Zeng CX, Yang Q, Hu Q. A comparison of the distribution of two glycyrrhizic acid epimers in rat tissues. Eur J Drug Metab Pharmacokinet. 2006;31:253-258. https://doi.org/10.1007/BF03190464
- Ha YM, Cheung AP, Lim P. Chiral separation of glycyrrhetinic acid by high-performance liquid chromatography. J Pharm Biomed Anal. 1991;9:805-809. https://doi.org/10.1016/0731-7085(91)80005-T
- Rossi T, Castelli M, Zandomeneghi G, Ruberto A, Benassi L, Magnoni C, et al. Selectivity of action of glycyrrhizin derivatives on the growth of MCF-7 and HEP-2 cells. Anticancer Res. 2003;23:3813-3818.
-
Shetty AV, Thirugnanam S, Dakshinamoorthy G, Samykutty A, Zheng G, Chen A, et al.
$18{\alpha}$ -glycyrrhetinic acid targets prostate cancer cells by down-regulating inflammation- related genes. Int J Oncol. 2011;39:635-640. https://doi.org/10.3892/ijo.2011.1061 -
Cai H, Chen X, Zhang J, Wang J.
$18{\beta}$ -glycyrrhetinic acid inhibits migration and invasion of human gastric cancer cells via the ROS/PKC-${\alpha}$ /ERK pathway. J Nat Med. 2018;72:252-259. https://doi.org/10.1007/s11418-017-1145-y -
Cao D, Jia Z, You L, Wu Y, Hou Z, Suo Y, et al.
$18{\beta}$ -glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p- Wnt-1 signaling. Oncotarget. 2016;7:71960-71973. https://doi.org/10.18632/oncotarget.12443 - Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol. 2007;35:495-516. https://doi.org/10.1080/01926230701320337
- Debnath J, Baehrecke EH, Kroemer G. Does autophagy contribute to cell death?. Autophagy. 2005;1:66-74. https://doi.org/10.4161/auto.1.2.1738
- Prevarskaya N, Skryma R, Shuba Y. Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?. Physiol Rev. 2018;98:559-621. https://doi.org/10.1152/physrev.00044.2016
- Kim BJ, Park EJ, Lee JH, Jeon JH, Kim SJ, So I. Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer. Cancer Sci. 2008;99:2502-2509. https://doi.org/10.1111/j.1349-7006.2008.00982.x
- Kim MC, Lee HJ, Lim B, Ha KT, Kim SY, So I, et al. Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. Int J Mol Med. 2014;33:1657-1663. https://doi.org/10.3892/ijmm.2014.1704
- Almasi S, Sterea AM, Fernando W, Clements DR, Marcato P, Hoskin DW, et al. TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway. Sci Rep. 2019;9:4182. https://doi.org/10.1038/s41598-019-40330-1
- Crociani O, Lastraioli E, Boni L, Pillozzi S, Romoli MR, D'Amico M, et al. hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications. Clin Cancer Res. 2014;20:1502-1512. https://doi.org/10.1158/1078-0432.CCR-13-2633