Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets

  • Oh, Seung Min (Gyeongbuk Livestock Research Institute) ;
  • Kim, Min Ju (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University) ;
  • Hosseindoust, Abdolreza (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University) ;
  • Kim, Kwang Yeol (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University) ;
  • Choi, Yo Han (Swine Division, National Institute of Animal Science, Rural Development Administration) ;
  • Ham, Hyung Bin (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University) ;
  • Hwang, Sung Jun (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University) ;
  • Lee, Jun Hyung (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University) ;
  • Cho, Hyun Jong (College of pharmacy, Kangwon National University) ;
  • Kang, Wei Soo (Department of Bio-Health Technology, College of Bio-Medical Science, Kangwon National University) ;
  • Chae, Byung Jo (Department of Animal Resources Science, College of Animal Life Sciences, Kangwon National University)
  • Received : 2019.02.19
  • Accepted : 2019.10.10
  • Published : 2020.06.01
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Abstract

Objective: This study was conducted to investigate the effects of hot-melt extruded ZnO nano-particles (HME-ZnO) as an alternative for P-ZnO on growth performance, nutrient digestibility, Zn bioavailability, intestinal microbiota, and intestinal morphology of weanling pigs. Methods: A total of 450 piglets (Landrace×Yorkshire×Duroc) were randomly allotted to five treatments based on initial body weight and sex. The experimental diets were fed in a meal form as phase 1 from d 0 to 14 and phase 2 from d 15 to 28. Treatments were the control diet without ZnO supplementation, the diet containing 2,500 ppm Zn as ZnO, and three diets containing 500, 1,000, or 2,500 ppm Zn as HME-ZnO. Results: The overall result showed a higher (p<0.01) average daily gain in weanling pigs fed ZnO-supplemented diets in comparison to the control diet. There was a decrease (p<0.01) in fecal score in the ZnO-supplemented diets. Dietary supplementation of ZnO improved (p<0.05) crude protein digestibility. The weanling pigs fed the P-ZnO diet had a lower (p<0.01) Zn digestibility in the feces than HME-ZnO supplemented treatments. Weanling pigs fed diets supplemented with ZnO had greater (p<0.05) Lactobacillus spp. populations and lower Clostridium spp. (p<0.05) and Coliforms (p<0.01) populations in the ileum. Weanling pigs fed diets supplemented with increasing concentrations of HME-ZnO linearly decreased Clostridium spp. (p<0.05) and Coliforms (p<0.01) in the ileum. Lower (p<0.05) Clostridium spp. and Coliforms counts in the colon were observed in pigs fed with ZnO-supplemented diets. Weanling pigs fed diets supplemented with ZnO showed a greater (p<0.01) villus height in the duodenum. Conclusion: Dietary supplementation of HME-ZnO and P-ZnO showed a potential to improve the digestibility of protein, intestinal Coliform and Clostridium, villus height in duodenum and ileum. Moreover, HME-ZnO showed a higher Zn digestibility compared with P-ZnO.

Keywords

References

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