융합정보논문지 (Journal of Convergence for Information Technology)

중소기업융합학회 (Convergence Society for SMB)
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Aspergillus oryzae로 제조한 Soybean koji 식이가 40-60대 중년여성의 손톱 개선에 미치는 영향

Effects of Soybean koji Prepared with Aspergillus oryzae on the Improvement of the Nails of in their 40s to 60s Women

  • 이성아 (건국대학교 대학원 생물공학과) ;
  • 강상모 (건국대학교 생물공학과)
  • Lee, Sung-A (Dept. of Biological Engineering, Graduate School, Konkuk University) ;
  • Kang, Sang-Mo (Dept. of Biological Engineering, Konkuk University)
  • 투고 : 2020.01.27
  • 심사 : 2020.03.20
  • 발행 : 2020.03.28
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초록

본 연구에서는 노화시작으로 손톱 상태가 나빠지는 중년 여성이 Aspergillus oryzae로 배양한 콩 koji를 섭취하므로 손톱의 건강상태가 얼마나 개선되는지를 알아보았다. 8주 동안 40~60대 여성을 대상으로 대조군은 삶은 비 발효 콩을, 시험군은 Aspergillus oryzae로 발효한 콩 koji를 섭취하도록 하였다. 연구결과 시험군의 손톱표면의 들뜸이나 갈라짐 상태가 개선되고, 수분량은 대조군에 비해 5.1배(p<.01), 수분 손실량은 대조군 감소량보다 1.4(p<.05)배, 손톱두께는 대조군에 비해 1.9(p<.05)배, 표면의 주름상태는 대조군에 비해 약 2.4(p<.01)배 정도 각각 개선됨을 보였다. 따라서 콩 koji 섭취가 손톱건강상태 개선에 영향을 미치는 것으로 나타났으며. 연구를 통하여 콩 koji가 이너뷰티 소재로서 활용이 가능할 것으로 기대한다.

The study was conducted to investigate the improvement nail health in middle-aged women aged 40~60 years who intake soybean koji by incubating Aspergillus oryzae(황국균), and utilized non-fermented soybeans as a control group and soybean koji as an experiment group for eight weeks. After clinical trials, the lifting and cracking conditions of the nails in the experiment group were improved, The moisture content increased 5.1 times compared to the control group, The water loss was 1.4 times less the reduction to the control group. and nail thickness increased by 1.9 times compared to controls. Wrinkles on the surface improved by about 2.4 times compared to the control group. In conclusion, consumption of this soybean koji of A. oryzae's has been shown to have an impact on improving nail is expected to be used Therefore, I propose this soybean koji of A. oryzae's as an inner beauty for improving nail is in middle-aged women aged 40~60 years.

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참고문헌

  1. E. Y. Shin & J. M. Lee. (2010). A Comparative Experiment of Nail Damage According to Removal Methods. Journal of The Korean Society of cosmetology, 16(2), 374-383.
  2. A. V. Rawlings & C. R. Harding. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(1), 43-48. DOI : 10.1111/j.1396-0296.2004.04S1005.x
  3. J. S. Kim & J. S Choi. (2003). Comparative Study on Nail Damage Grade ofPost-Treatment in Treating Nail Tip. Journal of The Korean Society of cosmetology, 9(3), 21-28.
  4. L. Farren, S. Shayler & A. R. Ennos.(2004). The fracture properties and mechanicaldesign of human fingernails. J Exp Biol, 207(5), 735-41. DOI :10.1242/jeb.00814
  5. Y. S. Jeon & S, M, Kang. (2009). Influence of collagen intake upon facial-skin wrinkles. Korean journal of aesthetics and cosmetics society, 18(2), 79-94.
  6. C. S. Kim. (2017). Effect of re-fermented Cheonggukjang and back meridian massage on facial skin and body type of middle-aged women, Doctoral dissertation. Konkuk University, Seoul.
  7. D. H. Jung & S .Watanabe. (2006). Soybean isoflavones, Seoul : shinilbooks.
  8. T. Nakata, D. Kyoui, H. Takahashi, B. Kimura & T. Kuda. (2017). Inhibitory effects of soybean oligosaccharides and water-soluble soybean fibre on formation of putrefactive compounds from soy protein by gut microbiota, Int J Biol Macromol, 97(3), 173-180. DOI :10.1016/j.ijbiomac.2017.01.015
  9. T. Roh, S. W. Kim, S. H. Moon & M. J. Nam, (2016). Genistein induces apoptosis by down-regulating thioredoxin-1 in human hepatocellular carcinoma SNU-449 cells, Food Chem Toxicol, 97(11), 127-134. https://doi.org/10.1016/j.fct.2016.09.003
  10. N .H. Park et al. (2013). Soybean extract showedmodulation of retinoic acid-related gene expression of skin and photo-protective effects in keratinocytes,Int J Cosmet Sci, 35(2), 136-42. DOI : 10.1111/ics.12014
  11. Y. M. Kim, J. S. Huh, Y. Lim and M. Cho, (2015). Soy Isoflavone Glycitin (4'-Hydroxy-6--Methoxyisoflavone-7-D-Glucoside)Promotes Human Dermal Fibroblast Cell Proliferation and Migration via TGF-$\beta$ Signaling, Phytother Res, 29(5), 57-69. DOI : 10.1002/ptr.5313
  12. E. J. Kim, M. K. Shim, A. R. Jeong, and A. J. Kim. (2019). Anti-photoaging Effects ofFermented Soybean (Bio-Peptone(R)), Cosmet.Scientists Korea, 45(1), 27-36.
  13. E. J. Kim & S. M. Kang. (2016). The Effectof Hydrogen Rich Water intake on 40's-60's Women's Facial Skin, Jounal of The Korean Society of cosmetology, 22(6), 1286-1296.
  14. J. H. Kim, J. S. Yoo, C. H. Lee, S. Y. Kim & S. K. Lee. (2006). Quality Properties of Soybean Pastes Made from Meju with MoldProducing Protease Isolated from TraditionalMeju, The Korean Society for AppliedBiological Chemistry, 49(1), 7-14.
  15. Y. H. Shon. (2005). Effects of Yellow Soybeans on skin, Master dissertation, Konkuk University, Seoul.
  16. D. H. Jung. (2000). fungus in daily life, Seoul : Yuhansa.
  17. S. I. Lee, Y. K. Lee, S. D. Kim. J. H. Lim, J. W. Suh & I. A. Lee. (2013). Anti-obesity Effect of Soybean Curd Residue Fermented by Genus Aspergillus, Journal of the KoreaAcademia-Industrial, 14(1), 5800-5808. DOI : 10.5762/KAIS.2013.14.11.5800
  18. C. H, Lin. Y. T. Wei & C. C. Chou. (2006). Enhanced Antioxidative Activity of SoybeanKoji Prepared with Various Filamentous Fungi, Food Microbiology, 23(7), 628-633. DOI : 10.1016/j.fm.2005.12.004
  19. S. B. Hong et al. (2015). Taxonomic-Characterization and Safety of Nuruk MoldsUsed Industrially in Korea, Mycobiology, 43(3), 149-157. DOI : 10.4489/KJM.2015.43.3.149
  20. K. M. Park. (2003). The Study of Nail Coloring -Degree of Demage on Nail by Concentration of Ace Tone. The Korean Association of Physical Arts, 4(2), 255-262
  21. S. I. Lee & Y. K. Lee. (2013). Anti-obesity Effect of Soybean Curd Residue Fermented by Genus Aspergillus, Journal of the Korean Academy of Science and Technology, 14(11), 5800-5808. DOI : 10.5762/KAIS.2013.14.11.5800
  22. E. J. Shin. (2012). Effects of complex dietary using collagen, egg White and vinegar on the opisthenar and nails of women in their 40s to 60s, A doctoral dissertation at Konkuk University, Seoul.
  23. R. K. Scher. RK. (1996). Onychomycosis: asignificant medical disorder. J Am AcadDermatol., 35(3), 2-5. DOI : 10.1016/S0190-9622(96)90061-4
  24. Farren. L, Shayler. S & A. R. Ennos. (2004).The fracture properties and mechanical design of human fingernails. J Exp Biol, 207(5), 735-41. DOI : http://dx.doi.org/10.1242/jeb.00814
  25. J. Kiers. (2001). Effects of Fermented SoyaBean on Digestion, Absorptionand Diarrhea,Doctoral dissertation Wageningen Universiteit, Wageningen Netherland.
  26. V. Zague. (2008). A new view concerning the effects of collagen hydrolysate intake on skin properties. Arch Dermatol Res, 300(9), 479-483. DOI : 10.1007/s00403-008-0888-4
  27. S. H. Myung. (2013). (A)study on preference, perception & consumption of Korean traditional salt conditioned & fermented foods : the case of Gang Won area residents, Master dissertation, Catholic Kwandong University, Gang Won.
  28. J. D. Kim, S. J. Kim H. S. Kim, K. H, Park,H. S. Lee & J. A. Jin. (2007), New CosmeticChemistry, Donghwatechnology.
  29. B. J. Ha. (1999). Cosmetic Science, Seoul : sumunsa.
  30. R. K. Lee & H. N. Cho. (2016). Manufacturing and Quality Characteristics of the Doenjang made with Aspergillus oryzae Strains Isolated in Korea, Microbiology and biotechnology letters, 44(1), 40-47. https://doi.org/10.4014/mbl.1511.11012
  31. Y. G. Kim. (2013). (The)dietary effect of royal jelly supplementation on epidermal levels offilaggrin, free amino acids and the relatedenzyme expression in ovariectomized rat, Master dissertation, Kyung Hee University, Seoul.
  32. P. M. Elias et al. (2002). Modulations in epidermal calcium regulate the expression ofdifferentiation-specific markers. J Invest Dermatol. 119(5), 1128-1136. DOI : 10.1046/j.1523-1747.2002.19512.x
  33. A. V. Rawlings & C. R. Harding. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(1), 43-48. DOI : 10.1111/j.1396-0296.2004.04S1005.x
  34. D. H. Baker, R. CBoitenthal, K. P. Boebel, G. L. Czarneck.i, L. L. Southern & G. M. Willis. (1981). Proetin-amino acid evaluation of steamprocessed feather meal, Journal of Poultry Science Association, 60(8), 1865-1872. https://doi.org/10.3382/ps.0601865
  35. C. Park. (2019). Effects of Soybean koji Prepared with Aspergillus oryzae for 40 -60s Women on Skin Aging Improvement, Doctoral dissertation, Konkuk University, Seoul.
  36. P. R. Holt. (1991). Gastrointestinal System : Changes in Morphology and Cell Proliferatio, Aging Clinical and Experimental Research, 3(4), 392-394. https://doi.org/10.1007/BF03324045
  37. R. M. Russell. (1992). Changes inGastrointestinal Function Attributed to Aging, The American Journal of Clinical Nutrition. 55(6), 1203-1207. DOI : 10.1093/ajcn/55.6.1203S
  38. M. K. Kim & S. M. Kang. (2015). The Effectof Collagen and Enzyme Food Intake on40's-60's Women's Facial Skin, Jounal of The Korean Society of cosmetology, 21(5),850-858.
  39. S. I. Lee & Y. K. Lee. (2013). Anti-obesity Effect of Soybean Curd Residue Fermented by Genus Aspergillus, Journal of the Korean Academy of Science and Technology, 14(11), 5800-5808.
  40. J. H. Lee. & Y. A. Song. (2015). Research about self awareness, lifestyle, and eating habit variables on nail health, Journal of the Korean Society for Health and Beauty. 6(2), 21-38.
  41. S. H. Liu. (2001). Studies on antioxidative effects and antioxidative components of soybean and Chongkukjang. Doctoral dissertation. Inje University, Gimhae.
  42. S. Y. Yoon. (1979). The Serum Ferritin levels in Iron Deficiency Anemia, Graduate School Chungnam National University, 6(2), 313-322.
  43. E. H. Seol & J. Y. Do. (2014). A Study of Current Status and Perception on Abnormal, The Korean Society of Beauty and Arts, 15(3), 197-208.
  44. J. M. Lohr, N. Panic, M. Vujasinovic & C. S. Verbeke(2018). The ageing pancreas a systematic review of the evidence andanalysis of the consequences, J Intern Med,283(5), 446-460. DOI : 10.1111/joim.12745
  45. T. Ishibashie et al. (1991). Aging and exocrine pancreatic function evaluated by the recently standardized secretin test, Nihon Ronen Igakkai Zasshi. 28(5), 599-605. https://doi.org/10.3143/geriatrics.28.599
  46. C. Park, Y. J. Cho & S. M. Kang. (2019), Effects of Soybean koji Prepared with Aspergillus oryzae for 40-60s Women on Facial Skin Condition, Journal of the Korean Society of Cosmetology, 25(2), 263-276.
  47. T. Nakata, D. Kyoui, H. Takahashi, B. Kimura& T. Kuda. (2017). Inhibitory effects of soybean oligosaccharides and water-soluble soybean fibre on formation of putrefactivecompounds from soy protein by gut microbiota,Int J Biol Macromol. 97(2017), 173-180. DOI : 10.1016/j.ijbiomac.2017.01.015