Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Antioxidant and anticoagulant activities of Ganghwa medicinal mugwort (Artemisia princeps Pampanini) extract

강화 약쑥 (Artemisia princeps Pampanini) 추출물의 항산화 및 항응고 활성

  • In, Man Jin (Department of Chemical Engineering, Chungwoon University) ;
  • Kim, Kang Hyun (Department of Chemical Engineering, Chungwoon University) ;
  • Kim, Dong Chung (Department of Chemical Engineering, Chungwoon University)
  • Received : 2020.11.04
  • Accepted : 2020.11.17
  • Published : 2020.12.31
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Abstract

In vitro antioxidant and anticoagulant activities of 50% ethanolic extract from Ganghwa medicinal mugwort (Artemisia princeps Pampanini) were investigated. The polyphenol and flavonoid contents of the mugwort extract were 106.9±3.3 and 34.1±0.4 mg/g-extract, respectively. The mugwort extract possessed a potent scavenging activity against radicals and nitrite, reducing power, and lipid peroxidation inhibition activity in a concentration-dependent manner. Also the mugwort extract delayed the plasma coagulation time through the inhibition of common coagulation pathway in a dose-dependent manner.

강화 사자발약쑥(Artemisia princeps Pampanini)으로부터 얻어진 50% 에탄올 추출물의 항산화 및 혈장 항응고 활성을 확인하였다. 약쑥 추출물의 폴리페놀과 플라보노이드 함량은 각각 106.9±3.3 및 34.1±0.4 mg/g-추출물로 나타났다. 약쑥 추출물은 농도 의존적으로 유리라디칼, 양이온라디칼 및 아질산염을 소거하였고, 우수한 환원력 및 지질과산화 억제효과를 나타내었다. 또한 약쑥 추출물은 농도 의존적으로 혈액응고의 공통경로를 저해하는 혈장 항응고 활성을 나타내었다.

Keywords

References

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