Korean Journal of Microbiology (미생물학회지)

The Microbiological Society of Korea (한국미생물학회)
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Draft genome sequence of Bacteroides sp. KGMB 02408 isolated from a healthy Korean feces

건강한 한국인 분변으로부터 분리된 Bacteroides sp. KGMB 02408 균주의 유전체 염기서열 초안

  • Yu, Seung Yeob (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Ji-Sun (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Oh, Byeong Seob (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Ryu, Seoung Woo (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Park, Seung-Hwan (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kang, Se Won (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Park, Jam-Eon (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Choi, Seung-Hyeon (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Han, Kook-Il (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Keun Chul (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Eom, Mi Kyung (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Suh, Min Kuk (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Han Sol (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Dong Ho (Seoul National University Bundang Hospital) ;
  • Yoon, Hyuk (Seoul National University Bundang Hospital) ;
  • Kim, Byung-Yong (ChunLab, Inc.) ;
  • Lee, Je Hee (ChunLab, Inc.) ;
  • Lee, Jung-Sook (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Ju Huck (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology)
  • 유승엽 (한국생명공학연구원 생물자원센터) ;
  • 김지선 (한국생명공학연구원 생물자원센터) ;
  • 오병섭 (한국생명공학연구원 생물자원센터) ;
  • 유승우 (한국생명공학연구원 생물자원센터) ;
  • 박승환 (한국생명공학연구원 생물자원센터) ;
  • 강세원 (한국생명공학연구원 생물자원센터) ;
  • 박잠언 (한국생명공학연구원 생물자원센터) ;
  • 최승현 (한국생명공학연구원 생물자원센터) ;
  • 한국일 (한국생명공학연구원 생물자원센터) ;
  • 이근철 (한국생명공학연구원 생물자원센터) ;
  • 엄미경 (한국생명공학연구원 생물자원센터) ;
  • 서민국 (한국생명공학연구원 생물자원센터) ;
  • 김한솔 (한국생명공학연구원 생물자원센터) ;
  • 이동호 (분당서울대학교병원) ;
  • 윤혁 (분당서울대학교병원) ;
  • 김병용 (천랩) ;
  • 이제희 (천랩) ;
  • 이정숙 (한국생명공학연구원 생물자원센터) ;
  • 이주혁 (한국생명공학연구원 생물자원센터)
  • Received : 2019.08.13
  • Accepted : 2019.09.04
  • Published : 2019.09.30
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Abstract

The genus of Bacteroides has been isolated from vertebrate animal feces. Bacteroides sp. KGMB 02408 was isolated from fecal samples obtained from a healthy Korean. The wholegenome sequence of Bacteroides sp. KGMB 02408 was analyzed using the PacBio Sequel platform. The genome comprises a 5,771,427 bp chromosome with a G + C content of 39.50%, 5,005 total genes, 18 rRNA genes, and 74 tRNA genes. Furthermore, we found that strain KGMB 02408 had some genes for oxidoreductases and menaquinone biosynthesis in its genome based on the result of genome analysis.

Bacteroides 속 균주들은 척추동물의 분변 등에서 분리된 것으로 알려져 있다. 본 연구에서는 건강한 한국인 분변으로부터 Bacteroides sp. KGMB 02408 균주를 분리하였으며 PacBio Sequel 플랫폼을 이용하여 Bacteroides sp. KGMB 02408 균주의 유전체서열을 분석하였다. 유전체는 G + C 구성 비율이 39.5%이고, 5,005개의 유전자와 rRNA 18개 tRNA 74개로 구성되었으며, 염색체의 크기는 5,771,427 bp였다. 또한, 유전체 분석 결과를 통해 산화-환원 효소와 메나퀴논 생합성 및 그와 관련된 다양한 유전자를 발견하였다.

Keywords

References

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