DOI QR코드

DOI QR Code

Clinical Effects of Intra-Abdominal Pressure in Critically Ill Trauma Patients

  • Ryu, Dong Yeon (Department of Trauma Surgery, Pusan National University Hospital) ;
  • Kim, Hohyun (Department of Trauma Surgery, Pusan National University Hospital) ;
  • Seok, June Pill (Department of Trauma Surgery, Wonkwang University Hospital) ;
  • Lee, Chan Kyu (Department of Trauma Surgery, Pusan National University Hospital) ;
  • Yeo, Kwang-Hee (Department of Trauma Surgery, Pusan National University Hospital) ;
  • Choi, Seon-Uoo (Department of Cardiovascular & Thoracic Surgery, Peruen Hospital) ;
  • Kim, Jae-Hun (Department of Trauma Surgery, Pusan National University Hospital) ;
  • Cho, Hyun Min (Department of Trauma Surgery, Pusan National University Hospital)
  • Received : 2018.11.14
  • Accepted : 2019.01.04
  • Published : 2019.06.30

Abstract

Purpose: There is increasing interest in intra-abdominal pressure (IAP) and intra-abdominal hypertension (IAH) in critically ill patients. This study investigated the effects and outcomes of elevated IAP in a trauma intensive care unit (ICU) population. Methods: Eleven consecutive critically ill patients admitted to the trauma ICU at Pusan National University Hospital Regional Trauma Center were included in this study. IAP was measured every 8-12 hours (intermittently) for 72 hours. IAP was registered as mean and maximal values per day throughout the study period. IAH was defined as $IAP{\geq}12mmHg$. Abdominal compartment syndrome was defined as $IAP{\geq}20mmHg$ plus ${\geq}1$ new organ failure. The main outcome measure was in-hospital mortality. Results: According to maximal and mean IAP values, 10 (90.9%) of the patients developed IAH during the study period. The Sequential Organ Failure Assessment (SOFA) score was significantly higher in patients with $IAP{\geq}20mmHg$ than in those with IAP <20 mmHg (16 vs. 5, p=0.049). The hospital mortality rate was 27.3%. Patients with a maximum $IAP{\geq}20mmHg$ exhibited significantly higher hospital mortality rates (p=0.006). Non-survivors had higher maximum and mean IAP values. Conclusions: Our results suggest that an elevated IAP may be associated with a poor prognosis in critically ill trauma patients.

Keywords

References

  1. Sugerman HJ. Increased intra-abdominal pressure in obesity. Int J Obes Relat Metab Disord 1998;22:1138. https://doi.org/10.1038/sj.ijo.0800757
  2. Rosenthal RJ, Friedman RL, Kahn AM, Martz J, Thiagarajah S, Cohen D, et al. Reasons for intracranial hypertension and hemodynamic instability during acute elevations of intra-abdominal pressure: observations in a large animal model. J Gastrointest Surg 1998;2:415-25. https://doi.org/10.1016/S1091-255X(98)80031-0
  3. Ishizaki Y, Itoh T, Shimomura K, Noie T, Abe H, Izezuki Y. Cardiovascular effects of increased intraabdominal pressure during pneumoperitoneum: preliminary report. Nippon Geka Gakkai Zasshi 1991;92:614.
  4. Rouby JJ, Puybasset L, Nieszkowska A, Lu Q. Acute respiratory distress syndrome: lessons from computed tomography of the whole lung. Crit Care Med 2003;31:S285-95. https://doi.org/10.1097/01.CCM.0000057905.74813.BC
  5. Polat C, Aktepe OC, Akbulut G, Yilmaz S, Arikan Y, Dilek ON, et al. The effects of increased intra-abdominal pressure on bacterial translocation. Yonsei Med J 2003;44:259-64. https://doi.org/10.3349/ymj.2003.44.2.259
  6. Markou N, Grigorakos L, Myrianthefs P, Boutzouka E, Rizos M, Evagelopoulou P, et al. Venous pressure measurements in the superior and inferior vena cava: the influence of intra-abdominal pressure. Hepatogastroenterology 2004;51:51-5.
  7. Reddy VG. Prevention of postoperative acute renal failure. J Postgrad Med 2002;48:64-70.
  8. Sugrue M, Jones F, Deane SA, Bishop G, Bauman A, Hillman K. Intra-abdominal hypertension is an independent cause of postoperative renal impairment. Arch Surg 1999;134:1082-5. https://doi.org/10.1001/archsurg.134.10.1082
  9. Malbrain ML, Chiumello D, Pelosi P, Bihari D, Innes R, Ranieri VM, et al. Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study. Crit Care Med 2005;33:315-22. https://doi.org/10.1097/01.CCM.0000153408.09806.1B
  10. Malbrain ML. Different techniques to measure intra-abdominal pressure (IAP): time for a critical re-appraisal. Intensive Care Med 2004;30:357-71. https://doi.org/10.1007/s00134-003-2107-2
  11. Kirkpatrick AW, Roberts DJ, De Waele J, Jaeschke R, Malbrain ML, De Keulenaer B, et al. Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. Intensive Care Med 2013;39:1190-206. https://doi.org/10.1007/s00134-013-2906-z
  12. Malbrain ML, Chiumello D, Pelosi P, Wilmer A, Brienza N, Malcangi V, et al. Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study. Intensive Care Med 2004;30:822-9. https://doi.org/10.1007/s00134-004-2169-9
  13. Malbrain ML. Is it wise not to think about intraabdominal hypertension in the ICU? Curr Opin Crit Care 2004;10:132-45. https://doi.org/10.1097/00075198-200404000-00010
  14. Cheatham ML, White MW, Sagraves SG, Johnson JL, Block EF. Abdominal perfusion pressure: a superior parameter in the assessment of intra-abdominal hypertension. J Trauma 2000;49:621-6. https://doi.org/10.1097/00005373-200010000-00008
  15. Doty JM, Oda J, Ivatury RR, Blocher CR, Christie GE, Yelon JA, et al. The effects of hemodynamic shock and increased intra-abdominal pressure on bacterial translocation. J Trauma 2002;52:13-7.
  16. Kotzampassi K, Metaxas G, Paramythiotis D, Pidonia I, Rekka H, Karamouzis M, et al. The influence of continuous seven-day elevated intra-abdominal pressure in the renal perfusion in cirrhotic rats. J Surg Res 2003;115:133-8. https://doi.org/10.1016/S0022-4804(03)00198-7